The Effect of Medical Advances on Insurance ... - Actuary.com

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TB Infection Cycle • Exposure to symptomatic infected person • Infection (silent) –> > positive PPD skin test - usually not infectious - treatment goal - prevent disease • Symptomatic Disease -> > cough, weight loss, fever, etc. – infectious stage - treatment goal: cure disease - lack <strong>of</strong> treatment: illness, contagion, death - inadequate treatment: illness, resistant TB forms arise, contagion, death
MDR-TB • Multi-drug resistant form – first cases 1990’s • 2/3 cases in Russia, India, China • 500,000 cases in 2005 • Resistant to first line drugs (INH, Rifampin) • Requires second line drugs – at least 18 months • Second line drugs – less effective, more costly, less available
Page 1 and 2: Medical Developmen
Page 3 and 4: Infectious Diseases Tuberculosis He
Page 5: TB Death Rate • 7% industrialized
Page 9 and 10: TB Remains a Treatable Disease •
Page 11 and 12: TB:Bottom Line • Serious illness
Page 13 and 14: Hepatitis A (HAV) • Spread by fec
Page 15 and 16: Chronic HBV in U.S. • 60,000 new
Page 17 and 18: HBV Control Challenge in U.S. • C
Page 19 and 20: Bottom Line - Chronic HBV • US re
Page 21 and 22: Impact of HCV •
Page 23 and 24: Stopping HCV Progression • Rate <
Page 25 and 26: Bottom Line: HCV • Chronic HCV an
Page 27 and 28: Business Continuity Planning 2007
Page 29 and 30: Occurrence of Infl
Page 31: Major Determinants of</stro
Page 34 and 35: US Dept HHS Projections Moderate (1
Page 36 and 37: WHO stages of pand
Page 38 and 39: Pandemic Planning • Pandemics- no
Page 40 and 41: Genetic Testing • Hot topic in DC
Page 42 and 43: Medicine of the Pa
Page 44: Landmarks in Genetics History • 1
Page 47 and 48: Mutations: Basis for Disease • A
Page 49 and 50: Causes of Mutation
Page 51 and 52: Beneficial Mutation
Page 53 and 54: Gene Studies • Detects mutations
Page 55 and 56: Single Gene Disorders • Follows M
Page 57 and 58:
Familial Aggregation
Page 59 and 60:
Recent Testing Advances</st
Page 61 and 62:
Challenge: Should Private Insurers
Page 63:
Stem Cells • Existing 20 stem cel
Page 66 and 67:
Childhood Cancer Survivors • Surv
Page 68 and 69:
Second Malignancies After Treatment
Page 70 and 71:
Summary • TB a global issue; MDR
Page 72 and 73:
Key Resources www.pandemicflu.gov w
Page 74:
Additional Pandemic Resources • S
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