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Smoking and mental health - NCSCT

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<strong>Smoking</strong> <strong>and</strong> <strong>mental</strong> <strong>health</strong><br />

heavy smokers <strong>and</strong> in those showing a therapeutic response to clozapine. 78–80<br />

Clozapine is the only atypical antipsychotic that consistently improves P50<br />

auditory gating, probably through serotonin (5HT 3<br />

) receptor antagonism, which<br />

increases acetylcholine release, 81 <strong>and</strong> hence activates nicotinic receptors which<br />

reduce the desire to smoke. Conversely, treatment with the older typical<br />

antipsychotics, such as haloperidol, has been associated with increased<br />

smoking. 79<br />

5.5 Provision of smoking cessation <strong>and</strong> tobacco dependence<br />

treatment for smokers with <strong>mental</strong> disorders in the UK<br />

The UK government’s <strong>mental</strong> <strong>health</strong> strategy (No <strong>health</strong> without <strong>mental</strong> <strong>health</strong>)<br />

has recently highlighted the need to adress the current higher mortality, lower<br />

levels of general <strong>health</strong>, <strong>and</strong> lower uptake of mainstream screening <strong>and</strong> public<br />

<strong>health</strong> programmes by people with <strong>mental</strong> disorders. 82 The identification of<br />

smokers with <strong>mental</strong> disorders, <strong>and</strong> provision of support to stop smoking<br />

through improved access to appropriate smoking cessation programmes, are<br />

described as critical objectives. 82 Smokers with <strong>mental</strong> disorders can access<br />

smoking cessation treatment services through a variety of avenues including their<br />

general (primary care) practitioner (GP), services provided by <strong>mental</strong> <strong>health</strong><br />

trusts <strong>and</strong> by self-enrolment with a local NHS SSS. These services, <strong>and</strong> the<br />

challenges that they present, are outlined below.<br />

5.5.1 Primary care<br />

As most people with <strong>mental</strong> disorders are managed in primary care, the role of<br />

the GP in providing smoking cessation <strong>and</strong> harm reduction treatment is crucial.<br />

This has recently been acknowledged in the integration of <strong>mental</strong> <strong>health</strong>-specific<br />

smoking-related outcomes into the Quality of Outcomes Framework (QOF), 83<br />

which is used to measure <strong>and</strong> incentivise GPs’ performance in the UK. The new<br />

indicators reward GPs for documenting smoking status regularly in patients with<br />

schizophrenia, bipolar disorder <strong>and</strong> other psychoses, <strong>and</strong> for providing smoking<br />

cessation advice or referral to an NHS SSS. 83 For the general population, brief<br />

advice by a practitioner, defined as the provision of ‘verbal instructions to stop<br />

smoking with or without added information about the harmful effects of<br />

smoking’, <strong>and</strong> requiring only 1 or 2 minutes of consultation time, achieves modest<br />

effects but is highly cost-effective. 84 Success can be increased by around 40% if<br />

more intensive advice is given with reinforcement by CO reading. 84 Although<br />

research into the effectiveness of brief <strong>and</strong> intensive advice for populations with<br />

<strong>mental</strong> disorders alone is lacking, there is no reason to believe that it would not<br />

achieve modest success in people with <strong>mental</strong> disorders, particularly if supported<br />

by appropriate prescribing of cessation pharmacotherapy.<br />

96 © Royal College of Physicians 2013

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