Tissue Banking Overview: Washington University Medical Center
Tissue Banking Overview: Washington University Medical Center
Tissue Banking Overview: Washington University Medical Center
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8/21/2012<br />
Specimen QA<br />
• Specimen identity<br />
• Important using whole genome technologies<br />
• Histological review of tissue specimens<br />
• <strong>Tissue</strong> viability, cellularity, disease representation<br />
• Conflicts in diagnosis<br />
• Molecular review of specimens<br />
• A260/A280 and A260/A230 ratios<br />
• Gel electrophoresis results<br />
• Feedback to biospecimen source / collectors<br />
Principles of specimen collection<br />
‣Specific, reproducible criteria are the most<br />
important, which are standardized as much as<br />
possible across the collection sites<br />
‣Clear, practical procedures are needed, with<br />
good communication essential<br />
‣<strong>Tissue</strong> bank users should understand<br />
collection practices and how they might<br />
impact their studies<br />
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