splice site
splice site
splice site
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TABLE 13-1<br />
Generated by Foxit PDF Creator © Foxit Software<br />
http://www.foxitsoftware.com For evaluation only.<br />
Three class of RNA Splicing<br />
Class<br />
Abundance<br />
Mechanism<br />
Catalytic<br />
Machinery<br />
Nuclear<br />
pre-<br />
mRNA<br />
Very common; used for<br />
most eukaryotic genes<br />
Two<br />
transesterification<br />
reactions; branch<br />
<strong>site</strong> A<br />
Major<br />
<strong>splice</strong>osome<br />
Group II<br />
introns<br />
Rare; some eu-Karyotic<br />
genes from organelles and<br />
prokaryotes<br />
Same as pre-<br />
mRNA<br />
RNA enzyme<br />
encoded by<br />
intron<br />
(ribozyme)<br />
Group I<br />
introns<br />
Rare; nuclear rRNA in<br />
some eukaryotics, organlle<br />
genes, and a few<br />
prokaryotic genes<br />
Two<br />
transesterific-<br />
ation reactions;<br />
exogenous G<br />
Same as<br />
group II<br />
introns