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TABLE 13-1<br />

Generated by Foxit PDF Creator © Foxit Software<br />

http://www.foxitsoftware.com For evaluation only.<br />

Three class of RNA Splicing<br />

Class<br />

Abundance<br />

Mechanism<br />

Catalytic<br />

Machinery<br />

Nuclear<br />

pre-<br />

mRNA<br />

Very common; used for<br />

most eukaryotic genes<br />

Two<br />

transesterification<br />

reactions; branch<br />

<strong>site</strong> A<br />

Major<br />

<strong>splice</strong>osome<br />

Group II<br />

introns<br />

Rare; some eu-Karyotic<br />

genes from organelles and<br />

prokaryotes<br />

Same as pre-<br />

mRNA<br />

RNA enzyme<br />

encoded by<br />

intron<br />

(ribozyme)<br />

Group I<br />

introns<br />

Rare; nuclear rRNA in<br />

some eukaryotics, organlle<br />

genes, and a few<br />

prokaryotic genes<br />

Two<br />

transesterific-<br />

ation reactions;<br />

exogenous G<br />

Same as<br />

group II<br />

introns

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