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4.3 A small group of intron are<br />

<strong>splice</strong>d by minor <strong>splice</strong>osome<br />

• Some pre-mRNAs are <strong>splice</strong>d by a low-<br />

abundance form of <strong>splice</strong>osome.This rare<br />

form contains some components common to<br />

the major <strong>splice</strong>osome but other unique<br />

components as well.<br />

• This minor <strong>splice</strong>osome recognizes rarely<br />

occuring introns having consensus<br />

sequences dinstict from the sequence of<br />

most pre-mRNA<br />

• Despite the different <strong>splice</strong> <strong>site</strong> and branch<br />

<strong>site</strong> sequences recognized by the two<br />

systems,these major and minor forms of<br />

<strong>splice</strong>osomes both remove introns using the<br />

same chemical pathway.

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