splice site
splice site
splice site
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The outcome of alternative splicing:<br />
1. Producing multiple protein products from a<br />
single gene, called isoforms.<br />
2. Switching on and off the expression of a given<br />
gene.<br />
(1)An exon contains a stop codon,when<br />
incorporated into mRNA,this prematurely<br />
terminates translation generating a truncated<br />
polypeptide.<br />
(2)Alternative splicing used as an on/off switch<br />
is by regulating the use of an intron,which,when<br />
retained in the mRNA ,ensure that species is not<br />
transported out of the nucleus and so is never<br />
translated.
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