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CLINICAL HANDBOOK OF SCHIZOPHRENIA
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© 2008 The Guilford PressA Divisio
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CONTRIBUTORSDonald Addington, MD, D
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ContributorsixGillian Haddock, PhD,
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ContributorsxiRoger H. Peters, PhD,
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PREFACESchizophrenia is arguably th
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Prefacexvcorporation of environment
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CONTENTSI. CORE SCIENCE AND BACKGRO
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ContentsxixCHAPTER 27 Illness Self-
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ContentsxxiCHAPTER 59 Sexuality 604
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CHAPTER 1HISTORY OF SCHIZOPHRENIAAS
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1. History of Schizophrenia 5ularly
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1. History of Schizophrenia 7PSYCHO
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1. History of Schizophrenia 9The ne
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1. History of Schizophrenia 11Since
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1. History of Schizophrenia 13Belli
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2. Epidemiology 15al., 2006), which
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2. Epidemiology 17not generally fou
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2. Epidemiology 19• Intrauterine
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2. Epidemiology 21function in socia
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2. Epidemiology 23KEY POINTS• Sch
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CHAPTER 3BIOLOGICAL THEORIESJONATHA
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3. Biological Theories 27cortex (in
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3. Biological Theories 29unchanged
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3. Biological Theories 31raclopride
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3. Biological Theories 33drives, mo
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CHAPTER 4BRAIN IMAGINGLISA T. EYLER
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4. Brain Imaging 37yet to be strong
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4. Brain Imaging 39with neuroleptic
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4. Brain Imaging 41events. However,
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4. Brain Imaging 43KEY POINTS• On
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5. Neuropathology 45TABLE 5.1. Summ
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5. Neuropathology 47schizophrenia i
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5. Neuropathology 49has been report
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5. Neuropathology 51also been demon
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5. Neuropathology 53results, especi
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CHAPTER 6GENETICSSTEPHEN J. GLATTTh
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6. Genetics 57Question 2: What Are
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6. Genetics 59nia. Each individual
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6. Genetics 61degree relatives desp
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6. Genetics 632A receptor (HTR2A) a
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CHAPTER 7ENVIRONMENTAL PRE-AND PERI
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7. Environmental Pre- and Perinatal
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7. Environmental Pre- and Perinatal
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7. Environmental Pre- and Perinatal
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7. Environmental Pre- and Perinatal
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8. Psychosocial Factors 75Steinberg
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8. Psychosocial Factors 77in terms
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8. Psychosocial Factors 79This mode
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8. Psychosocial Factors 81KEY POINT
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9. Psychopathology 83ations; change
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9. Psychopathology 85sity School of
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9. Psychopathology 87or “loose as
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9. Psychopathology 89lished WHO. Th
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CHAPTER 10COGNITIVE FUNCTIONINGIN S
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10. Cognitive Functioning in Schizo
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10. Cognitive Functioning in Schizo
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10. Cognitive Functioning in Schizo
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10. Cognitive Functioning in Schizo
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11. Course and Outcome 101DIAGNOSIS
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11. Course and Outcome 103TABLE 11.
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11. Course and Outcome 105DOMAINS O
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11. Course and Outcome 107mation gi
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11. Course and Outcome 109quency of
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11. Course and Outcome 111to a smal
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11. Course and Outcome 113spectivel
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CHAPTER 12DIAGNOSTIC INTERVIEWINGAB
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12. Diagnostic Interviewing 119psyc
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12. Diagnostic Interviewing 121not
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12. Diagnostic Interviewing 123tual
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CHAPTER 13ASSESSMENT OFCO-OCCURRING
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Time-Line Follow-BackThe Time-Line
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Testing and Risk Assessment for Inf
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13. Co-Occurring Disorders 131test
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13. Co-Occurring Disorders 133can i
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CHAPTER 14ASSESSMENT OFPSYCHOSOCIAL
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14. Assessment of Psychosocial Func
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TABLE 14.1. Measures of Psychosocia
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14. Assessment of Psychosocial Func
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14. Assessment of Psychosocial Func
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CHAPTER 15TREATMENT PLANNINGALEXAND
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15. Treatment Planning 147WHAT DOES
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15. Treatment Planning 149TABLE 15.
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15. Treatment Planning 151Poor adhe
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Occupational/School Functioning15.
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15. Treatment Planning 155Drake, R.
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CHAPTER 16ANTIPSYCHOTICSERIC C. KUT
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16. Antipsychotics 161for at least
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TABLE 16.3. Dosing of the First-Gen
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16. Antipsychotics 165are not avail
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16. Antipsychotics 167• Therapeut
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17. Side Effects of Antipsychotics
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17. Side Effects of Antipsychotics
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17. Side Effects of Antipsychotics
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17. Side Effects of Antipsychotics
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17. Side Effects of Antipsychotics
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18. Clozapine 179Plasma concentrati
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TABLE 18.1. Clinical tips for cloza
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18. Clozapine 183linergic effects t
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18. Clozapine 185• Common side ef
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19. Other Medications 187agitation
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19. Other Medications 189Small, ope
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19. Other Medications 191ANTIDEPRES
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19. Other Medications 193sation in
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19. Other Medications 195Citrome, L
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20. Electroconvulsive Therapy 197TA
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20. Electroconvulsive Therapy 199FI
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Missed SeizuresIf no seizure occurs
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20. Electroconvulsive Therapy 203(C
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PART IVPSYCHOSOCIAL TREATMENT
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208 IV. PSYCHOSOCIAL TREATMENTdisin
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210 IV. PSYCHOSOCIAL TREATMENTFIGUR
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212 IV. PSYCHOSOCIAL TREATMENTschiz
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CHAPTER 22FAMILY INTERVENTIONCHRIST
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216 IV. PSYCHOSOCIAL TREATMENTTABLE
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218 IV. PSYCHOSOCIAL TREATMENTcommi
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220 IV. PSYCHOSOCIAL TREATMENTother
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222 IV. PSYCHOSOCIAL TREATMENTtient
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224 IV. PSYCHOSOCIAL TREATMENTButzl
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CHAPTER 23COGNITIVE-BEHAVIORAL THER
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228 IV. PSYCHOSOCIAL TREATMENTThe a
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230 IV. PSYCHOSOCIAL TREATMENTAndre
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232 IV. PSYCHOSOCIAL TREATMENTFIGUR
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234 IV. PSYCHOSOCIAL TREATMENTtion.
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236 IV. PSYCHOSOCIAL TREATMENTnever
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238 IV. PSYCHOSOCIAL TREATMENTwith
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CHAPTER 24SOCIAL SKILLS TRAININGWEN
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242 IV. PSYCHOSOCIAL TREATMENTeach
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244 IV. PSYCHOSOCIAL TREATMENTThe m
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246 IV. PSYCHOSOCIAL TREATMENTCogni
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248 IV. PSYCHOSOCIAL TREATMENT• S
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250 IV. PSYCHOSOCIAL TREATMENTThe d
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252 IV. PSYCHOSOCIAL TREATMENTNone
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254 IV. PSYCHOSOCIAL TREATMENT• I
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256 IV. PSYCHOSOCIAL TREATMENTnance
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- Page 329: PART VSYSTEMS OF CARE
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- Page 345 and 346: Resource Acquisition32. Strengths-B
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35. Treatment in Jails and Prisons
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Pharmacological Treatment35. Treatm
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35. Treatment in Jails and Prisons
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PART VISPECIAL POPULATIONSAND PROBL
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368 VI. SPECIAL POPULATIONS AND PRO
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370 VI. SPECIAL POPULATIONS AND PRO
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372 VI. SPECIAL POPULATIONS AND PRO
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374 VI. SPECIAL POPULATIONS AND PRO
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376 VI. SPECIAL POPULATIONS AND PRO
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378 VI. SPECIAL POPULATIONS AND PRO
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CHAPTER 37TREATMENT OF THESCHIZOPHR
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382 VI. SPECIAL POPULATIONS AND PRO
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384 VI. SPECIAL POPULATIONS AND PRO
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386 VI. SPECIAL POPULATIONS AND PRO
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388 VI. SPECIAL POPULATIONS AND PRO
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CHAPTER 38OLDER INDIVIDUALSTHOMAS W
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392 VI. SPECIAL POPULATIONS AND PRO
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394 VI. SPECIAL POPULATIONS AND PRO
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396 VI. SPECIAL POPULATIONS AND PRO
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CHAPTER 39UNDERSTANDING AND WORKING
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400 VI. SPECIAL POPULATIONS AND PRO
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402 VI. SPECIAL POPULATIONS AND PRO
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404 VI. SPECIAL POPULATIONS AND PRO
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406 VI. SPECIAL POPULATIONS AND PRO
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408 VI. SPECIAL POPULATIONS AND PRO
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410 VI. SPECIAL POPULATIONS AND PRO
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412 VI. SPECIAL POPULATIONS AND PRO
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414 VI. SPECIAL POPULATIONS AND PRO
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416 VI. SPECIAL POPULATIONS AND PRO
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418 VI. SPECIAL POPULATIONS AND PRO
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420 VI. SPECIAL POPULATIONS AND PRO
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422 VI. SPECIAL POPULATIONS AND PRO
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CHAPTER 41MEDICAL COMORBIDITYINGRID
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426 VI. SPECIAL POPULATIONS AND PRO
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428 VI. SPECIAL POPULATIONS AND PRO
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430 VI. SPECIAL POPULATIONS AND PRO
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432 VI. SPECIAL POPULATIONS AND PRO
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434 VI. SPECIAL POPULATIONS AND PRO
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436 VI. SPECIAL POPULATIONS AND PRO
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438 VI. SPECIAL POPULATIONS AND PRO
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440 VI. SPECIAL POPULATIONS AND PRO
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442 VI. SPECIAL POPULATIONS AND PRO
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444 VI. SPECIAL POPULATIONS AND PRO
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446 VI. SPECIAL POPULATIONS AND PRO
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448 VI. SPECIAL POPULATIONS AND PRO
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450 VI. SPECIAL POPULATIONS AND PRO
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452 VI. SPECIAL POPULATIONS AND PRO
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454 VI. SPECIAL POPULATIONS AND PRO
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456 VI. SPECIAL POPULATIONS AND PRO
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458 VI. SPECIAL POPULATIONS AND PRO
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460 VI. SPECIAL POPULATIONS AND PRO
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462 VI. SPECIAL POPULATIONS AND PRO
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464 VI. SPECIAL POPULATIONS AND PRO
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466 VI. SPECIAL POPULATIONS AND PRO
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468 VI. SPECIAL POPULATIONS AND PRO
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470 VI. SPECIAL POPULATIONS AND PRO
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472 VI. SPECIAL POPULATIONS AND PRO
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474 VI. SPECIAL POPULATIONS AND PRO
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476 VI. SPECIAL POPULATIONS AND PRO
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478 VI. SPECIAL POPULATIONS AND PRO
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480 VI. SPECIAL POPULATIONS AND PRO
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482 VI. SPECIAL POPULATIONS AND PRO
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484 VI. SPECIAL POPULATIONS AND PRO
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486 VI. SPECIAL POPULATIONS AND PRO
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488 VI. SPECIAL POPULATIONS AND PRO
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490 VI. SPECIAL POPULATIONS AND PRO
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492 VI. SPECIAL POPULATIONS AND PRO
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494 VI. SPECIAL POPULATIONS AND PRO
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496 VI. SPECIAL POPULATIONS AND PRO
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498 VI. SPECIAL POPULATIONS AND PRO
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500 VI. SPECIAL POPULATIONS AND PRO
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502 VI. SPECIAL POPULATIONS AND PRO
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504 VI. SPECIAL POPULATIONS AND PRO
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CHAPTER 48THE ECONOMICSOF SCHIZOPHR
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Indirect Costs48. The Economics of
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48. The Economics of Schizophrenia
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48. The Economics of Schizophrenia
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48. The Economics of Schizophrenia
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Commitment in Different Jurisdictio
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49. Involuntary Commitment 519It ha
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POLICY AND SOCIAL IMPLICATIONSEvide
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49. Involuntary Commitment 523sion
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50. Jail Diversion 525of law enforc
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50. Jail Diversion 527several disti
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Plan50. Jail Diversion 529The goal
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50. Jail Diversion 531cates that ja
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CHAPTER 51STIGMAPATRICK W. CORRIGAN
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Label Avoidance51. Stigma 535Label
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51. Stigma 537the first episode dep
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51. Stigma 539Disclosing One’s Me
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CHAPTER 52EVIDENCE-BASED PRACTICESM
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52. Evidence-Based Practices 543•
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52. Evidence-Based Practices 545fel
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52. Evidence-Based Practices 547nat
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CHAPTER 53SCHIZOPHRENIA INDEVELOPIN
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53. Schizophrenia in Developing Cou
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53. Schizophrenia in Developing Cou
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53. Schizophrenia in Developing Cou
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CHAPTER 54REMISSIONBERNARD A. FISCH
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54. Remission 561ery generally mean
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54. Remission 563verity. Instrument
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54. Remission 565ScalesAndreason, N
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55. Recovery 567ways of thinking ab
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55. Recovery 569often learn lessons
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55. Recovery 571associated with her
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55. Recovery 573cian must become co
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CHAPTER 56GENDERMARY V. SEEMANGende
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56. Gender 577irritability and defi
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56. Gender 579accounted for by wome
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CHAPTER 57QUALITY OF LIFESTEFAN PRI
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57. Quality of Life 583different co
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57. Quality of Life 585Specifically
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57. Quality of Life 587FACTORS INFL
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Use in Treatment57. Quality of Life
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57. Quality of Life 591Community su
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58. Spirituality and Religion 593in
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58. Spirituality and Religion 595cl
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58. Spirituality and Religion 597Th
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58. Spirituality and Religion 599an
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58. Spirituality and Religion 601co
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58. Spirituality and Religion 603
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59. Sexuality 605• Sexual activit
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59. Sexuality 607sion leader follow
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59. Sexuality 609abundant positive
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59. Sexuality 611vignettes, explici
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59. Sexuality 613teaching the subje
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59. Sexuality 615Crenshaw, T. L., &
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60. Schizophrenia in African Americ
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60. Schizophrenia in African Americ
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60. Schizophrenia in African Americ
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60. Schizophrenia in African Americ
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61. Ethics 625on two important ethi
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61. Ethics 627hospitals, and resear
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61. Ethics 629Despite these seeming
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INDEXPage numbers followed by findi
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Index 633Assessment of Interpersona
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Index 635problem maintenance and, 2
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Index 637Emergency room visits, 339
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Index 639metabolism of, 166tduring
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Index 641Lifestyle factors, 21comor
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Index 643side effectsin adolescents
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Index 645not otherwise specified, i
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Index 647Self-management strategies
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Index 649Synapsin, 49Synapsin II ge