Shift-work disorderthe other potentially causative conditions. (Examplesof how mood disorders and other sleep/wake disorderscan be differentiated from SWD appear below.)Mood disorders and sleep/wake disorders oftenpresent in the primary care setting and can at first seemindistinguishable. For example, patients with ES as a resultof a sleep/wake disorder may superficially appearto have depression, as a lack of energy, poor memory,reduced concentration, and a loss of interest in lifeare <strong>com</strong>mon features of both ES and mood disorders.In such instances, asking the patient about his or hersleep habits and the use of simple depression questionnairessuch as the Patient Health Questionnaire-9(www.patient.co.uk/showdoc/40025272/) are vital toavoid misdiagnosis and prescription of inappropriatemedication.ES is also a symptom of the sleep/wake disordersobstructive sleep apnea (OSA) and restless legs syndrome(RLS), which are <strong>com</strong>monly reported in shiftworkers. 26,27 Patients with OSA have poor quality sleep,as they experience repeated full or partial blockages oftheir airway, resulting in snoring and episodes of chokingor gasping during sleep. 28 Recurrent partial or <strong>com</strong>pleteobstruction of the upper airway leads to repeatedarousals and disturbed sleep, which can cause ES. 29,30Night-shift work has been shown to aggravate OSA, 31possibly due to the increased potential for weight gainand metabolic disturbance in this population 24 ; overweightand metabolic syndrome are risk factors for and<strong>com</strong>orbidities associated with OSA. 28 It is imperativethat patients with suspected OSA are referred to a sleepspecialist as well as counseled about appropriate therapiesand lifestyle changes. 32RLS may develop in shift workers due to low serumiron levels induced by chronic sleep deprivation. 33 Patientswith symptoms of RLS should have their serumferritin levels checked and, if found to be
References1. American Academy of Sleep Medicine. Internationalclassification of sleep disorders and codingmanual. 2nd ed. Westchester, IL: AmericanAcademy of Sleep Medicine; 2005.2. Marquié JC, Foret J. Sleep, age, and shiftwork experience.J Sleep Res. 1999;8:297-304.3. Marquié JC, Foret J, Queinnec Y. Effects of age,working hours, and job content on sleep: a pilotstudy. Exp Aging Res. 1999;25:421-427.4. Schwartz JR, Roth T. Shift work sleep disorder:burden of illness and approaches to management.Drugs. 2006;66:2357-2370.5. Shen J, Botly LC, Chung SA, et al. Fatigue andshift work. J Sleep Res. 2006;15:1-5.6. Drake CL, Roehrs T, Richardson G, et al. Shiftwork sleep disorder: prevalence and consequencesbeyond that of symptomatic day workers.Sleep. 2004;27:1453-1462.7. Waage S, Moen BE, Pallesen S, et al. Shift workdisorder among oil rig workers in the North Sea.Sleep. 2009;32:558-565.8. Ohayon MM, Lemoine P, Arnaud-Briant V, et al.Prevalence and consequences of sleep disordersin a shift worker population. J Psychosom Res.2002;53:577-583.9. Czeisler CA, Moore-Ede MC, Coleman RH. Rotatingshift work schedules that disrupt sleep areimproved by applying circadian principles. Science.1982;217:460-463.10. Härmä M, Tarja H, Irja K, et al. A controlled interventionstudy on the effects of a very rapidly forwardrotating shift system on sleep-wakefulnessand well-being among young and elderly shiftworkers. Int J Psychophysiol. 2006;59:70-79.11. Dumont M, Benhaberou-Brun D, Paquet J. Profileof 24-h light exposure and circadian phaseof melatonin secretion in night workers. J BiolRhythms. 2001;16:502-511.12. Koller M, Kundi M, Stidl HG, et al. Personal lightdosimetry in permanent night and day workers.Chronobiol Int. 1993;10:143-155.13. Crowley SJ, Lee C, Tseng CY, et al. Complete orpartial circadian re-entrainment improves performance,alertness, and mood during nightshiftwork. Sleep. 2004;27:1077-1087.14. Axelsson J, Åkerstedt T, Kecklund G, et al. Toleranceto shift work—how does it relate to sleepand wakefulness? Int Arch Occup EnvironHealth. 2004;77:121-129.15. Takahashi M, Nakata A, Haratani T, et al. Psychosocialwork characteristics predicting daytimesleepiness in day and shift workers. ChronobiolInt. 2006;23:1409-1422.16. Härmä M, Knauth P, Ilmarinen J, et al. The relationof age to the adjustment of the circadianrhythms of oral temperature and sleepiness toshift work. Chronobiol Int. 1990;7:227-233.17. Härmä MI, Hakola T, Åkerstedt T, et al. Age andadjustment to night work. Occup Environ Med.1994;51:568-573.18. Smith L, Mason C. Reducing night shift exposure:a pilot study of rota, night shift and ageeffects on sleepiness and fatigue. J Hum Ergol(Tokyo). 2001;30:83-87.19. Sack RL, Auckley D, Auger RR, et al. Circadianrhythm sleep disorders: part I, basic principles,shift work and jet lag disorders. An AmericanAcademy of Sleep Medicine review. Sleep.2007;30:1460-1483.20. Oginska H, Pokorski J, Oginski A. Gender, ageing,and shiftwork intolerance. Ergonomics.1993;36:161-168.21. Ostberg O. Interindividual differences in circadianfatigue patterns of shift workers. Br J IndMed. 1973;30:341-351.22. Hilliker NA, Muehlbach MJ, Schweitzer PK, et al.Sleepiness/alertness on a simulated night shiftschedule and morningness-eveningness tendency.Sleep. 1992;15:430-433.23. Morgenthaler TI, Lee-Chiong T, Alessi C, et al.Practice parameters for the clinical evaluationand treatment of circadian rhythm sleep disorders.An American Academy of Sleep Medicinereport. Sleep. 2007;30:1445-1459.24. Härmä M, Tenkanen L, Sjöblom T, et al. Combinedeffects of shift work and life-style on theprevalence of insomnia, sleep deprivationand daytime sleepiness. Scand J Work EnvironHealth. 1998;24:300-307.25. Doghramji K. Assessment of excessive sleepinessand insomnia as they relate to circadianrhythm sleep disorders. J Clin Psychiatry. 2004;65(suppl 16):17-22.26. Ohayon MM, Roth T. Prevalence of restless legssyndrome and periodic limb movement disorderin the general population. J Psychosom Res.2002;53:547-554.27. Paim SL, Pires ML, Bittencourt LR, et al. Sleep<strong>com</strong>plaints and polysomnographic findings:a study of nuclear power plant shift workers.Chronobiol Int. 2008;25:321-331.28. Pagel JF. The burden of obstructive sleep apneaand associated excessive sleepiness. J Fam Pract.2008;57(suppl 8):S3-S8.29. Pagel JF. Excessive daytime sleepiness. Am FamPhysician. 2009;79:391-396.30. Veasey SC, Davis CW, Fenik P, et al. Long-termintermittent hypoxia in mice: protracted hypersomnolencewith oxidative injury to sleep-wakebrain regions. Sleep. 2004;27:194-201.31. Laudencka A, Klawe JJ, Tafil-Klawe M, et al.Does night shift work induce apneic events inobstructive sleep apnea patients? J Physiol Pharmacol.2007;58(suppl 5):S345-S347.32. Doghramji PP. Recognition of obstructive sleepapnea and associated excessive sleepiness in primarycare. J Fam Pract. 2008;57:(suppl 8):S17-S23.33. Barton JC, Wooten VD, Acton RT. Hemochromatosisand iron therapy of restless legs syndrome.Sleep Med. 2001;2:249-251.34. Silber MH, Ehrenberg BL, Allen RP, et al. Analgorithm for the management of restless legssyndrome. Mayo Clin Proc. 2004;79:916-922.35. Johns MW. A new method for measuring daytimesleepiness: the Epworth sleepiness scale.Sleep. 1991;14:540-545.Supplement to The Journal of Family Practice • Vol 59, No 1 / January 2010 S23
- Page 1 and 2:
Practice Management Tips ForSHIFT W
- Page 3 and 4:
Patient QuestionnaireDo you often f
- Page 5 and 6:
Sleep/Wake LogIn bedOut of bedLight
- Page 7 and 8:
PHQ-9 QUICK DEPRESSION ASSESSMENTFo
- Page 9 and 10:
Insomnia Severity IndexPlease answe
- Page 11 and 12:
Take-Away PointsSHIFT WORK DISORDER
- Page 13 and 14: SHIFT WORKDISORDERBright Light Ther
- Page 40 and 41: PrimarycareScreeningfor depressioni
- Page 42 and 43: PrimarycareThescreening questionnai
- Page 44 and 45: Shift-work disorderContents and Fac
- Page 46 and 47: Shift-work disorderThe diagnosis of
- Page 48 and 49: Shift-work disorderas heightened le
- Page 50 and 51: Shift-work disorderFigure 1 Risk ra
- Page 52 and 53: Shift-work disorderare not function
- Page 54 and 55: The characterization andpathology o
- Page 56 and 57: Shift-work disorderFigure 2 Sleep/w
- Page 58 and 59: Shift-work disorderFigure 3 Blood p
- Page 60 and 61: Recognition of shift-workdisorder i
- Page 62 and 63: Shift-work disorderThe timing of sh
- Page 66 and 67: Managing the patient withshift-work
- Page 68 and 69: Shift-work disorderFigure 3 Optimal
- Page 70 and 71: Shift-work disorderfor a motor vehi
- Page 72 and 73: Shift-work disordermoderate caffein
- Page 74 and 75: Supplement toAvailable at jfponline
- Page 76 and 77: Armodafinil for Treatment of Excess
- Page 78 and 79: Armodafinil for Treatment of Excess
- Page 80 and 81: Armodafinil for Treatment of Excess
- Page 82 and 83: Armodafinil for Treatment of Excess
- Page 84 and 85: Armodafinil for Treatment of Excess
- Page 86 and 87: Armodafinil for Treatment of Excess
- Page 88 and 89: Armodafinil for Treatment of Excess
- Page 90 and 91: Armodafinil for Treatment of Excess
- Page 92 and 93: Armodafinil for Treatment of Excess
- Page 94 and 95: Armodafinil for Treatment of Excess
- Page 96 and 97: Armodafinil for Treatment of Excess
- Page 98 and 99: The Epidemiology and Diagnosis of I
- Page 100 and 101: The Epidemiology and Diagnosis of I
- Page 102 and 103: The Epidemiology and Diagnosis of I
- Page 120 and 121:
CIRCADIAN RHYTHM SLEEP DISORDERSPra
- Page 122 and 123:
Table 2— AASM Levels of Recommend
- Page 124 and 125:
3.2.1.1 Both the Morningness-Evenin
- Page 126 and 127:
Five studies used one of the newer
- Page 128 and 129:
as an indicator of phase in sighted
- Page 130 and 131:
4.4 Advanced Sleep Phase DisorderBe
- Page 132 and 133:
45. Walsh, JK, Randazzo, AC, Stone,
- Page 134:
123. Van Someren, EJ, Kessler, A, M
- Page 142 and 143:
Table 1—Subject Demographicsn M:F
- Page 144 and 145:
Scale. 28 The simple reaction time
- Page 146 and 147:
Median RT (msec)1600A14001200100080
- Page 148 and 149:
10Mentally AExhaustedSharpScore8642
- Page 150 and 151:
Current Treatment Options in Neurol
- Page 152 and 153:
398 Sleep Disordersand sleep loss,
- Page 154 and 155:
400 Sleep DisordersTable 1. Treatme
- Page 156 and 157:
402 Sleep DisordersStandard dosageC
- Page 158 and 159:
404 Sleep DisordersStandard procedu
- Page 160 and 161:
406 Sleep DisordersCaffeineMelatoni
- Page 162 and 163:
408 Sleep DisordersWake-promoting a
- Page 164 and 165:
410 Sleep Disordersnight shift: ada