- Page 3 and 4:
For Alexander and SarinaWith all ou
- Page 5 and 6:
First edition 1989Second edition fi
- Page 7 and 8:
viPrefacepublishers, who I am sure,
- Page 9 and 10:
viiiAcknowledgementsFig 6.5 is repr
- Page 11 and 12:
Table of Contents1. Cell Membranes,
- Page 13 and 14:
xiiContentsGASTRIC pH .............
- Page 15 and 16:
xivContents9. Nasal Drug Delivery .
- Page 18 and 19:
Chapter OneCell Membranes, Epitheli
- Page 20 and 21:
Membranes and barriers 3Figure 1.1
- Page 22 and 23:
Membranes and barriers 5Modulation
- Page 24 and 25:
Membranes and barriers 7Membrane pr
- Page 26 and 27:
Membranes and barriers 9Figure 1.6
- Page 28 and 29:
Membranes and barriers 11Figure 1.9
- Page 30 and 31:
Membranes and barriers 13Figure 1.1
- Page 32 and 33:
Membranes and barriers 15Figure 1.1
- Page 34 and 35:
Membranes and barriers 17Figure 1.1
- Page 36 and 37:
Chapter TwoParenteral Drug Delivery
- Page 38 and 39:
Parenteral drug delivery 21Figure 2
- Page 40 and 41:
Parenteral drug delivery 23catheter
- Page 42 and 43:
Parenteral drug delivery 25Figure 2
- Page 44 and 45:
Parenteral drug delivery 27Figure 2
- Page 46 and 47:
Parenteral drug delivery 29fluid is
- Page 48 and 49:
Parenteral drug delivery 31Figure 2
- Page 50 and 51:
Parenteral drug delivery 33Receptor
- Page 52:
Parenteral drug delivery 3526. Tsuj
- Page 55 and 56:
38 Physiological PharmaceuticsANATO
- Page 57 and 58:
40 Physiological PharmaceuticsFigur
- Page 59 and 60:
42 Physiological Pharmaceuticsgland
- Page 61 and 62:
44 Physiological PharmaceuticsABSOR
- Page 63 and 64:
46 Physiological PharmaceuticsThe r
- Page 65 and 66:
48 Physiological Pharmaceuticsa) in
- Page 67 and 68:
50 Physiological Pharmaceuticswhen
- Page 69 and 70:
52 Physiological Pharmaceuticsin de
- Page 71 and 72:
54 Physiological PharmaceuticsFigur
- Page 73 and 74:
56 Physiological Pharmaceutics8. We
- Page 75 and 76:
58 Physiological Pharmaceutics59. A
- Page 77 and 78:
60 Physiological PharmaceuticsINTRO
- Page 79 and 80:
62 Physiological PharmaceuticsFigur
- Page 81 and 82:
64 Physiological PharmaceuticsTable
- Page 83 and 84:
66 Physiological Pharmaceuticsliqui
- Page 85 and 86:
68 Physiological PharmaceuticsFigur
- Page 87 and 88:
70 Physiological PharmaceuticsTable
- Page 89 and 90:
72 Physiological Pharmaceutics12. W
- Page 92 and 93:
Chapter FiveThe StomachANATOMY AND
- Page 94 and 95:
The stomach 77Figure 5.2 Structure
- Page 96 and 97:
The stomach 79Gastric glandsThe gas
- Page 98 and 99:
The stomach 81Figure 5.7 Mechanism
- Page 100 and 101:
The stomach 83absorbed from the sto
- Page 102 and 103:
The stomach 85Night-time transient
- Page 104 and 105:
The stomach 87particle size indiges
- Page 106 and 107:
The stomach 89Figure 5.13 MRI cross
- Page 108 and 109: The stomach 91species and man is po
- Page 110 and 111: The stomach 93Figure 5.15 The effec
- Page 112 and 113: The stomach 95emerged from the shel
- Page 114 and 115: The stomach 97Figure 5.17 The gastr
- Page 116 and 117: The stomach 99In order to improve b
- Page 118 and 119: The stomach 101Figure 5.21—Gastri
- Page 120 and 121: The stomach 103The anatomy and dime
- Page 122 and 123: The stomach 10533:1283-1290.35. Cun
- Page 124 and 125: The stomach 10782. Ingani HM, Timme
- Page 126 and 127: Chapter SixDrug Absorption from the
- Page 128 and 129: Small intestine 111Figure 6.1 Secti
- Page 130 and 131: Small intestine 113are uncommon and
- Page 132 and 133: Small intestine 115underlying tissu
- Page 134 and 135: Small intestine 117Brief periodic b
- Page 136 and 137: Small intestine 119is extremely rap
- Page 138 and 139: Small intestine 121Figure 6.5 Segme
- Page 140 and 141: Small intestine 123Measurements of
- Page 142 and 143: Small intestine 125Figure 6.8 Small
- Page 144 and 145: Small intestine 127Scintigraphy oft
- Page 146 and 147: Small intestine 129It is known that
- Page 148 and 149: Small intestine 131It was soon real
- Page 150 and 151: Small intestine 133colonic absorpti
- Page 152 and 153: Small intestine 135also transform d
- Page 154 and 155: Small intestine 137REFERENCES1. Bry
- Page 156 and 157: Small intestine 13949. Hidalgo IJ,
- Page 160 and 161: Chapter SevenDrug Delivery to the L
- Page 162 and 163: Colon and rectal drug delivery 145F
- Page 164 and 165: Colon and rectal drug delivery 147r
- Page 166 and 167: Colon and rectal drug delivery 149T
- Page 168 and 169: Colon and rectal drug delivery 151C
- Page 170 and 171: Colon and rectal drug delivery 153i
- Page 172 and 173: Colon and rectal drug delivery 155t
- Page 174 and 175: Colon and rectal drug delivery 157L
- Page 176 and 177: Colon and rectal drug delivery 159T
- Page 178 and 179: Colon and rectal drug delivery 161D
- Page 180 and 181: Colon and rectal drug delivery 163O
- Page 182 and 183: Colon and rectal drug delivery 165T
- Page 184 and 185: Colon and rectal drug delivery 167F
- Page 186 and 187: Colon and rectal drug delivery 169F
- Page 188 and 189: Colon and rectal drug delivery 171A
- Page 190 and 191: Colon and rectal drug delivery 173A
- Page 192 and 193: Colon and rectal drug delivery 1751
- Page 194 and 195: Colon and rectal drug delivery 1776
- Page 196 and 197: Colon and rectal drug delivery 1791
- Page 198 and 199: Chapter EightTransdermal Drug Deliv
- Page 200 and 201: Transdermal drug delivery 183Epider
- Page 202 and 203: Transdermal drug delivery 185the up
- Page 204 and 205: Transdermal drug delivery 187respon
- Page 206 and 207: Transdermal drug delivery 189temper
- Page 208 and 209:
Transdermal drug delivery 191PENETR
- Page 210 and 211:
Transdermal drug delivery 193b) The
- Page 212 and 213:
Transdermal drug delivery 195avoida
- Page 214 and 215:
Transdermal drug delivery 19745. Bu
- Page 216 and 217:
Chapter NineNasal Drug DeliveryANAT
- Page 218 and 219:
Nasal drug delivery 201Figure 9.2 B
- Page 220 and 221:
Nasal drug delivery 203The nasal cy
- Page 222 and 223:
Nasal drug delivery 205penetration
- Page 224 and 225:
Nasal drug delivery 207change in th
- Page 226 and 227:
Nasal drug delivery 209Figure 9.4 E
- Page 228 and 229:
Nasal drug delivery 211chamber with
- Page 230 and 231:
Nasal drug delivery 213Figure 9.6 C
- Page 232 and 233:
Figure 9.8 Fraction of benzoic acid
- Page 234 and 235:
Nasal drug delivery 217REFERENCES1.
- Page 236 and 237:
Nasal drug delivery 21951. Anik ST,
- Page 238 and 239:
Chapter TenPulmonary Drug DeliveryS
- Page 240 and 241:
Pulmonary drug delivery 223toward t
- Page 242 and 243:
Pulmonary drug delivery 225Figure 1
- Page 244 and 245:
Pulmonary drug delivery 227Lung per
- Page 246 and 247:
Pulmonary drug delivery 229can dest
- Page 248 and 249:
Pulmonary drug delivery 231of these
- Page 250 and 251:
Pulmonary drug delivery 233Figure 1
- Page 252 and 253:
Pulmonary drug delivery 235Nebulize
- Page 254 and 255:
Pulmonary drug delivery 237ASSESSME
- Page 256 and 257:
Pulmonary drug delivery 239Labeling
- Page 258 and 259:
Pulmonary drug delivery 241Depositi
- Page 260 and 261:
Pulmonary drug delivery 243Compound
- Page 262 and 263:
Pulmonary drug delivery 245clearanc
- Page 264:
Pulmonary drug delivery 24731. Coad
- Page 267 and 268:
250 Physiological PharmaceuticsINTR
- Page 269 and 270:
252 Physiological PharmaceuticsImme
- Page 271 and 272:
254 Physiological PharmaceuticsFigu
- Page 273 and 274:
256 Physiological PharmaceuticsFigu
- Page 275 and 276:
258 Physiological PharmaceuticsFigu
- Page 277 and 278:
260 Physiological Pharmaceutics2. t
- Page 279 and 280:
262 Physiological PharmaceuticsEffe
- Page 281 and 282:
264 Physiological Pharmaceuticsß-D
- Page 283 and 284:
266 Physiological PharmaceuticsFigu
- Page 285 and 286:
268 Physiological PharmaceuticsIntr
- Page 287 and 288:
270 Physiological Pharmaceutics15.
- Page 289 and 290:
272 Physiological PharmaceuticsANAT
- Page 291 and 292:
274 Physiological PharmaceuticsFigu
- Page 293 and 294:
276 Physiological PharmaceuticsEnzy
- Page 295 and 296:
278 Physiological PharmaceuticsA ma
- Page 297 and 298:
280 Physiological PharmaceuticsIntr
- Page 300 and 301:
GlossaryAα-amylase Enzymes which h
- Page 302 and 303:
Glossary 285solution by the blood i
- Page 304 and 305:
Glossary 287Diffusion coefficient C
- Page 306 and 307:
Glossary 289Glucose-6-phosphate deh
- Page 308 and 309:
Glossary 291Lactose Disaccharide th
- Page 310 and 311:
Glossary 295of a long alkyl chain,
- Page 312 and 313:
Glossary 297Stratum corneum Outermo
- Page 314 and 315:
IndexAα-adrenergic agonists 208, 2
- Page 316 and 317:
Index 301Cholecystokinin 113, 148,
- Page 318 and 319:
Index 303Ethylcellulose 262Ethylene
- Page 320 and 321:
Index 305Indomethacin 165, 172Infer
- Page 322 and 323:
Index 307Multi-drug resistance 130M
- Page 324 and 325:
Index 309Gastric emptying 92Preoper
- Page 326 and 327:
Index 311Sublingual tablet 49Substa