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Type B insulin resistance Pathogenesis of Hypoglycemia IR-A for hyperglycemia insulin antagonist in high titer accelerated receptor degradation receptor downregulation IR-A for hypoglycemia insulin agonist in low titer
IR-AType B insulin resistance Polyclonal IgGs, which may becomposed of varioussubpopulation of immunoglobulinswith varying agonist or antagonistactivity toward the insulin receptor In support of this hypothesis, Sestiand co-workers demonstrated thattwo IgG subfractions from apatient with IR-A andhypoglycemia differed in theirability to inhibit insulin binding tothe two distinct human insulinreceptor subtypesSesti G, Diabetes. 1992
Page 1 and 2: Autoimmune Hypoglycemia2010. 05. 08
Page 3 and 4: Introduction Hypoglycemia incidence
Page 5 and 6: IntroductionAutoimmune causes Insul
Page 7 and 8: Insulin Autoimmune Syndrome First o
Page 9 and 10: Insulin Autoimmune Syndrome Clinica
Page 11 and 12: Insulin Autoimmune Syndrome Pathoge
Page 13 and 14: Insulin Autoimmune Syndrome Origin
Page 15 and 16: Insulin Autoimmune Syndrome Numerou
Page 17 and 18: Insulin Autoimmune Syndrome Altered
Page 19 and 20: Insulin Autoimmune Syndrome Course
Page 21 and 22: Type B insulin resistance In 1975,
Page 23: Type B insulin resistance Laborator
Page 27 and 28: Type B insulin resistance Diagnosis
Page 29 and 30: Type B insulin resistance Course an
Page 31: Summary
Page 34: 감 사 합 니 다A
Page 38 and 39: Insulin Autoimmune Syndrome Laborat
Page 40 and 41: Interpretation of values after 72 h
Page 42 and 43: Target autoantigens in type 1 diabe
Page 44: Introduction IA have also been demo

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