Microsoft PowerPoint - S14-1_\300\374\274\272\277\317 [\310\243 ...
Microsoft PowerPoint - S14-1_\300\374\274\272\277\317 [\310\243 ...
Microsoft PowerPoint - S14-1_\300\374\274\272\277\317 [\310\243 ...
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Insulin immunogenecity Insulin autoantibodies(IA) 1% to 8% of healthy subjects without diabetes or autoimmune disease 40% of newly diagnosed type 1 diabetic patients 30% of nondiabetic patients with other autoimmune disease 10% of patients receiving alpha-interferon for chronic viral hepatitisDi Cerbo A, J Endocrinol Invest. 1995Di Mario U, Acta Endocrinol. 1990Palmer J, Diabetes Metab Rev. 1987Wilkin TJ, Endocr Rev. 1990