Nutrition and Oral Medicine (Nutrition and Health)

90Table 1Drugs That Can Result in Nutrient DeficitsDrug Examples Nutrient Deficit Possible Clinical SignsAlcohol Folic acid, thiamine, vit. C, niacin, Peripheral neuropathy, angular stomatitis,vit. B 2 , vit. B 6 , vit. B 12 , Mg, zinc cheilitis, glossitisAnalgesics Salicylates Folate, vit. C AnemiaAntacids Aluminum hydroxide, sodium Folic acid, Ca, Mg, Cu, Fe, phosphate, Osteomalaciabicarbonate Zn, KAntibacterial agents General All B vitamins, vit. C, and KTrimethoprim Folic acid Anemia, glossitis, cheilitisSulfa Folic acid Anemia, glossitis, cheilitisTetracyclines Vit. B 6 , vit. B 12 , Ca, Mg, Zn Peripheral neuropathy, angular stomatitis,cheilitis, glossitisAminoglycosides (Neomycin) Vit. B 12 , vit. A, vit. K; Ca, Fe, Mg, K +Anticoagulants Coumadin Vit. K HemorrhageAnticonvulsants Phenobarbital, phenytoin, primidone Folic acid, vit. B 12 , vit. D, Ca OsteomalaciaCarbamazepine, Tegretol Folic acid Megaloblastic anemia, glossitis, cheilitisOral hypoglycemic agents Sulfonylureas ThiamineBiguanides (metformin) Vit. B 12 Megaloblastic anemiaAnti-inflammatory agents Corticosteroids Vit. D, Ca, Zn, K Osteopenia, osteoporosisPrednisone Ca OsteopeniaGout medication (colchicine) Vit. K, vit. B 12 , vit. A, K, NaSulfasalazine Folic acid Anemia, glossitis, cheilitisAspirin Folic acid, vit. C, Fe, protein Anemia, glossitis, cheilitisNSAIDs Folic acid Anemia, glossitis, cheilitisAnti-Parkinson drugs L-Dopa Vit. B 6 Peripheral neuropathy, angular stomatitis,cheilitis, glossitis90 Part II / Oral and General Health