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Breast cancer<br />

Breast cancer drug rejected for NHS use on<br />

cost-benefit grounds<br />

Charities angered by guidance on Kadcyla, which costs £90,000 per year per patient and gives extra<br />

nine months on average<br />

A consultant analysing a mammogram. Photograph: Rui Vieira/PA<br />

Sarah Boseley Health editor<br />

Thursday <strong>29</strong> December <strong>2016</strong> 00.01 GMT Last modified on Thursday <strong>29</strong> December <strong>2016</strong> 00.04 GMT<br />

A breast cancer drug that costs £90,000 a year per patient has been turned down for use by the NHS<br />

on financial grounds, triggering an outcry from patients groups who say it prolongs the lives of people<br />

seriously ill with the disease.<br />

Kadcyla, made by Roche Pharmaceuticals, was rejected by the National Institute for Health and Care<br />

Excellence. It has the highest price tag ever for a cancer medicine and was turned down because its<br />

benefits did not justify its cost, Nice said.<br />

Prof Carole Longson, director of the centre for health technology evaluation at Nice, said: “We know<br />

that people with cancer place great importance on drugs that can increase their life expectancy. For<br />

that reason we apply as much flexibility as we can when we look at new life-extending treatments.<br />

“But the reality is that the price of trastuzumab emtansine [the generic name for Kadcyla] is currently<br />

too high in relation to the benefits it gives for it to be recommended for routine commissioning in the<br />

NHS, even taking into account the end-of-life criteria and the patient access scheme.”<br />

<strong>The</strong> charity Breast Cancer Now launched a petition against what it called a disastrous decision and<br />

“a huge setback for the treatment of advanced breast cancer”, while Breast Cancer Care said the<br />

decision was unacceptable.

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