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Shingles<br />

Shingles (herpes zoster) is a reactivation of the varicella zoster virus – also called<br />

herpesvirus 3, the same virus that causes chickenpox (see Childhood Diseases<br />

and Immunisation).<br />

Chickenpox generally occurs in children and young people. However, once an<br />

episode of chickenpox has resolved, the virus is not eliminated from the body<br />

but lies dormant in nerve cells close to the spinal cord. Many years later it can<br />

reactivate to cause shingles, an infection with symptoms vastly different from the<br />

original chickenpox infection. Exactly how the virus remains latent in the body,<br />

and subsequently reactivates, is not understood.<br />

Shingles occurs only in people who have had chickenpox, and people whose<br />

immune systems are impaired due to ill health, medications, or diseases that<br />

lower the immunity (eg, cancer, HIV) are most at risk. Occasionally, trauma (eg, a<br />

surgical scar) may trigger shingles at the site of the injury. Contact with somebody<br />

who currently has varicella or herpes zoster may also cause reactivation. Shingles<br />

can occur at any age but is more common in adults aged over 60. Rarely, shingles<br />

may occur in young children who were either born with chickenpox or had it soon<br />

after birth. Most people get shingles only once in their lifetime.<br />

Symptoms of shingles<br />

Early symptoms may include non-specific complaints, such as headache, fever<br />

and malaise, which may be easily misdiagnosed. After a couple of days, itching,<br />

tingling, numbness or burning, and/or a stabbing pain may develop in the<br />

affected dermatome (an area of skin supplied by one spinal nerve). Usually, after<br />

one or two days (but sometimes as long as three weeks), the initial phase is<br />

followed by the appearance of the characteristic skin rash.<br />

The pain and rash most commonly occur on the areas of skin supplied by<br />

the thoracic (chest), cervical (neck), ophthalmic (forehead), and lumbar (torso)<br />

nerves. The rash usually starts as a crop of red papules and may look like hives<br />

but, since the virus spreads along certain nerves located off the spinal cord, it<br />

typically has a stripe-like and usually unilateral presentation, unlike hives which<br />

are usually widespread. Within a few days, the papules form small, painful,<br />

exudate-filled blisters, which may persist for up to seven to 10 days before they<br />

crust over and heal.<br />

Once the blisters have appeared, and until the rash has developed crusts, a<br />

person is extremely contagious and transmission of the virus can occur to people<br />

without immunity to the virus. These people may then develop chickenpox but<br />

will not immediately develop shingles.<br />

Shingles may be associated with serious complications including postherpetic<br />

neuralgia, bacterial superinfection, infection of internal organs, visual<br />

impairment, hearing loss and death. Sometimes after severe blistering, scarring<br />

and discoloured skin may remain.<br />

Initial assessment<br />

Avoid close contact with somebody with suspected shingles if you have never<br />

TREATMENT OPTIONS<br />

Category Examples Comments<br />

Oral analgesics<br />

Topical pain relievers<br />

Varicella vaccine<br />

Natural / herbal products /<br />

supplements<br />

[GENERAL SALE]<br />

eg, paracetamol (Panadol, Paracare), ibuprofen<br />

up to 25s (Advil, Nurofen)<br />

[PHARMACY ONLY MEDICINE]<br />

eg, paracetamol – greater than 20 tablets,<br />

suspension (Pamol All Ages, Paracare, Panadol),<br />

ibuprofen >25s (Advil, Nurofen), ibuprofen +<br />

paracetamol (Maxigesic, Nuromol)<br />

[GENERAL SALE]<br />

eg, capsaicin cream (Zostrix HP*), lignocaine<br />

preparations (Soov cream/spray)<br />

[PHARMACY ONLY MEDICINE]<br />

eg, lignocaine/prilocaine (Emla), aspirin (

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