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2017 HCHB_digital

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Asthma and COPD<br />

Asthma<br />

New Zealand has one of the highest prevalences of asthma in the world and over<br />

460,000 people regularly take medication for asthma. An estimated one in seven<br />

children and one in nine adults are affected, and only a small number of children<br />

appear to grow out of the condition.<br />

Common symptoms include wheezing (a whistling sound most obvious when<br />

breathing out), shortness of breath, tightness in the chest, difficulty speaking, and<br />

a persistent dry cough (usually at night or after exercise). Over time this cough may<br />

become more productive. A cough may be the only symptom in young children.<br />

These symptoms may occur suddenly as an asthma “attack”, or they can be<br />

present most of the time. During an “attack”, breathing becomes very difficult<br />

due to inflammation and contraction of the smooth muscle within the airway,<br />

excessive mucous secretion, and swelling of the smaller airways. Permanent<br />

damage of the airways can result from untreated asthma.<br />

It is common for asthmatics to also suffer from hay fever or eczema, and/or to<br />

have a family history of these conditions.<br />

The cause of asthma is unknown; however, many common triggers have been<br />

identified, including animal dander (especially cats), cigarette smoke, cold air,<br />

exercise, house dust mites, pollen, stress, strong perfume, viral infections (eg, a<br />

cold) and some medicines (eg, aspirin and NSAIDs). Asthma cannot be cured but<br />

TREATMENT OPTIONS<br />

Category Examples Comments<br />

Relievers<br />

(short-acting<br />

bronchodilators)<br />

Preventers<br />

Short-acting muscarinic<br />

antagonists (SAMA) or<br />

long-acting muscarinic<br />

antagonists (LAMA)<br />

Symptom controllers:<br />

long-acting beta2<br />

agonists (LABA)<br />

Combination therapy<br />

Spacers<br />

Beta2-agonists<br />

[PRESCRIPTION MEDICINE]<br />

eg, salbutamol inhaler (Asthalin, SalAir,<br />

Salamol, Respigen, Ventolin)<br />

eg, terbutaline (Bricanyl)<br />

eg, salbutamol liquid (Ventolin)<br />

Inhaled corticosteroids (ICS)<br />

[PRESCRIPTION MEDICINE]<br />

eg, beclomethasone (Beclazone, Qvar),<br />

budesonide (Pulmicort), fluticasone<br />

propionate (Floair, Flixotide)<br />

Mast cell stabilisers and others<br />

[PRESCRIPTION MEDICINE]<br />

eg, nedocromil (Tilade), sodium<br />

cromoglycate (Intal Spincaps/Forte),<br />

montelukast (Singulair)<br />

[PRESCRIPTION MEDICINE]<br />

eg, ipratropium (Atrovent, Univent)<br />

tiotropium (Spiriva), glycopyrronium<br />

(Seebri), umeclidinium (Incruse Ellipta),<br />

aclidinium (Bretaris)<br />

[PRESCRIPTION MEDICINE]<br />

eg, eformoterol (Foradil, Oxis), indacaterol<br />

(Onbrez), salmeterol (Meterol, Serevent)<br />

[PRESCRIPTION MEDICINE]<br />

eg, eformoterol + budesonide (Symbicort<br />

Smart, Vannair), glycopyrronium<br />

+ indacaterol (Ultibro Breezhaler),<br />

ipratropium + salbutamol (Duolin HFA),<br />

salmeterol + fluticasone propionate<br />

(RexAir, Seretide), tiotropium + olodaterol<br />

(Spiolto Respimat), umeclidinium +<br />

vilanterol (Anoro), vilanterol + fluticasone<br />

furoate (Breo)<br />

eg, e-chamber, Volumatic<br />

Children aged six or less<br />

eg, e-chamber mask<br />

Reliever inhalers are used to treat the acute symptoms of asthma (ie, the difficulty in breathing). They provide<br />

relief within a couple of minutes. Most reliever inhalers are blue.<br />

Anyone using a reliever more than three times a week or waking at night with symptoms should go to the<br />

doctor. If a person finds his bronchodilator has become less effective, it may indicate worsening asthma and<br />

the need to initiate an action plan or to visit the doctor to review therapy.<br />

Preventer inhalers contain ICS. They do not have an immediate effect, so nothing is felt after inhalation;<br />

however, when used regularly they reduce the underlying inflammation of the airways and help reduce the<br />

incidence and severity of asthma attacks and hospitalisations. Most preventer inhalers are either brown,<br />

orange or dark red. Reduce risk of oral thrush by using a spacer and rinsing the mouth with water after using<br />

ICS.<br />

Mast cell stabilisers (ie, nedocromil, sodium cromoglycate) are not commonly used since they are less effective<br />

than ICSs. May be useful for preventing exercise-induced asthma. Sodium cromoglycate needs to be taken<br />

anywhere from four to eight times daily. They may take up to six weeks to take effect.<br />

Montelukast is a leukotriene receptor antagonist that may be used in addition to ICSs for an additive effect.<br />

Can be of benefit in exercise-induced asthma and in people who also have rhinitis. Special Authority needed.<br />

Ipratropium reduces mucous secretions and relaxes airway muscle. It is short-acting and has a slower onset of<br />

action than beta2-agonists so is used more in COPD, although certain asthma patients may benefit. Longer<br />

acting antimuscarinic bronchodilators include tiotropium, glycopyrronium, umeclidinium, and aclidinium.<br />

Long-acting bronchodilators. Do not treat the underlying inflammation but may be beneficial in mild to<br />

moderate asthma instead of using higher doses of ICS. Used in conjunction with an ICS. Not useful for acute<br />

asthma attacks since they do not open airways immediately. Do not exceed recommended dose.<br />

Combination agents may aid adherence to recommended preventative regimens.<br />

Please refer to detailed product information as well as asthma guidelines to distinguish when combination<br />

inhalers should be used, and which combinations are recommended depending on the severity of the asthma<br />

or COPD.<br />

Dispense<br />

Ventolin ®<br />

The original blue inhaler<br />

that Kiwis know and trust 2<br />

Help to improve delivery of MDIs to the lungs, reduce adverse effects of ICSs. Wash once a week with warm<br />

water and a squirt of detergent and allow to completely drip dry. This leaves a slight residue of detergent<br />

on the inside of the spacer which reduces static and stops the medicine in the inhaler sticking to the sides.<br />

Replace every six to 12 months (tiny scratches or abrasions can prevent the spacer working as effectively).<br />

VENTOLIN<br />

Asthma<br />

Symptom Relief<br />

doesn’t need to involve an<br />

unpleasant aftertaste. 1<br />

DISPENSE<br />

ALCOHOL<br />

FREE<br />

VENTOLIN 2<br />

Page VEN_XXXX_Ventoline 16 HEALTHCARE Strip Ad Marc HANDBOOK 17 V3.indd 1 <strong>2017</strong>-2018 Common Disorders

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