An Interactive Introduction to Organismal and Molecular Biology, 2021

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PROTEIN SYNTHESIS I: TRANSCRIPTION | 151 Now let’s test your understanding of transcription regulation! Take the quiz below the simulation as you work your way through it. Note that if you are using your mouse to scroll down, it may not work at this point—use the scrolling bar at the right edge of your web browser instead. An interactive or media element has been excluded from this version of the text. You can view it online here: https://openbooks.lib.msu.edu/isb202/?p=274 An interactive or media element has been excluded from this version of the text. You can view it online here: https://openbooks.lib.msu.edu/isb202/?p=274 The Process of Transcription: A Detailed Look This chapter began with an overview of transcription and then focused more deeply on the role of the polymerase and regulatory proteins. Now watch the following video. It is an in-depth version of the first video of this chapter, incorporating aspects described throughout this chapter. An interactive or media element has been excluded from this version of the text. You can view it online here: https://openbooks.lib.msu.edu/isb202/?p=274 References 1. Gilbert, S. F. (2000). Anatomy of the gene: Promoters and enhancers. In Developmental biology (6th ed.). Sunderland, MA: Sinauer Associates. Retrieved from https://www.ncbi.nlm.nih.gov/books/ NBK10023/#_A751_. 2. Gilbert, S. F. (2000). Silencers. In Developmental biology (6th ed.). Sunderland, MA: Sinauer Associates.
152 | PROTEIN SYNTHESIS I: TRANSCRIPTION Retrieved from http://www.ncbi.nlm.nih.gov/books/NBK10023/#_A777_. 3. Menke, D. B., Guenther, C., and Kingsley, D. M. (2008). Dual hindlimb control elements in the Tbx4 gene and region-specific control of bone size in vertebrate limbs. Development, 135, 2543-2553. http://dx.doi.org/10.1242/dev.017384. 4. Wray, Gregory A. (2007). The evolutionary significance of cis-regulatory mutations. Nature Reviews Genetics, 8, 206-216. http://dx.doi.org/10.1038/nrg2063. 5. Reece, J. B., Urry, L. A., Cain, M. L., Wasserman, S. A., Minorsky, P. V., and Jackson, R. B. (2011). Combinatorial control of gene activation. In Campbell Biology (10th ed., pp. 37). San Francisco, CA: Pearson. 6. Reményi, Attila, Hans R. Schöler, and Matthias Wilmanns. (2004). Combinatorial control of gene expression. Nature Structural & Molecular Biology, 11(9), 812. http://dx.doi.org/10.1038/nsmb820. Retrieved from http://www.nature.com/scitable/content/Combinatorial-control-of-geneexpression-16976. Attributions This chapter is a modified derivative of the following articles: “Regulated Transcription” by Molecular and Cellular Biology Learning Center, Virtual Cell Animation Collection, CC BY-NC-ND 4.0. “Transcription” by Molecular and Cellular Biology Learning Center, Virtual Cell Animation Collection, CC BY-NC-ND 4.0. “Transcription Factors” by Khan Academy, CC BY-NC-SA 4.0. All Khan Academy content is available for free at (www.khanacademy.org). Media Attributions • Central Dogma (Transcription) © Andrea Bierema • general transcription factors © Khan Academy is licensed under a CC BY-NC-SA (Attribution NonCommercial ShareAlike) license • activator © Khan Academy is licensed under a CC BY-NC-SA (Attribution NonCommercial ShareAlike) license • repressors © Khan Academy is licensed under a CC BY-NC-SA (Attribution NonCommercial ShareAlike) license • binding sites © Khan Academy is licensed under a CC BY-NC-SA (Attribution NonCommercial ShareAlike) license • enhancers © Khan Academy is licensed under a CC BY-NC-SA (Attribution NonCommercial ShareAlike) license • activators and repressors © Khan Academy is licensed under a CC BY-NC-SA (Attribution NonCommercial ShareAlike) license
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An Interactive Introduction to Orga
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INTRODUCTION Andrea Bierema This
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UNIT I INTRODUCTION TO SCIENCE
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