Effects of isochaborat testosterone on the kidney rats

Review of Literature
Review of Literature
Anabolic Androgenic Steroids (AAS) commonly known as anabolic steroids
which are a large group of molecules including endogenously produced androgens
such as, testosterone as well as synthetically manufactured derivatives (Al-Aubody
and Al-Diwan, 2018).
Testosterone and Nandrolone Decanoate (ND) are the most commonly abused
androgens. AAS used were and still widespread due to their ability to improve muscle
growth for athletes' performance and minimizing androgenic effects. Indeed,
androgens are able to increase the size of muscle fibers as well as muscle strength and
while their used was initially restricted to professional bodybuilders, nowadays it has
become more popular among recreational athletes (Tirla et al., 2021).
AAS have anabolic properties which widely used for therapeutic purposes.
Indeed, AAS had a role in the treatment of chronic kidney disease and osteoporosis in
postmenopausal women, as well as terminal stage of breast cancer. However, used of
AAS for the forbidden by the World Anti-Doping Agency (WADA). However, AAS
used was still very popular and 1–3% of US inhabitants have been estimated to be
AAS users ( Althobiti et al., 2018).
However, AAS have side effects involving all organs. Therefore, their abuse
was considered a public health issue. In this regard, an increased awareness is needed
among the population and healthcare workers, both for diagnostic, therapeutic and
prevention purposes of AAS (Tirla et al., 2021).
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