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1952 Afr. J. Pharm. Pharmacol. Figure 2. The levels of BUN and Cr of plasma in four groups. Data presented means ±SD. **P
Chen et al. 1953 Figure 4. Concentration of TNF-α, IL-1 and IL-6 of plasma in four groups. (A) IL-1; (B); IL-6; (C) TNF-α. Data presented means ±SD. **P < 0.01 versus sham group; #P < 0.05, ## P 0.05) were lower than group TH (48.7 ± 7.9 U/g). MDA content in group TH + PHC was lower than group TH + ANI, but no significant difference was found in these two groups (P > 0.05). On the other hand, MPO activity in group TH + PHC was lower than group TH + ANI (P < 0.05). The concentrations of,IL-1, IL-6, TNF-α in plasma Figure 4 shows the data of IL-1 (Figure 4A), IL-6 (Figure 4B) and TNF-α (Figure 4C) concentration in plasma. Compared with sham group (IL-1: 9.8 ± 3.1 pg/ml; IL-6: 16.8 ± 7.4 pg/ml; TNF-α: 6.4 ± 3.7 pg/ml), the concentrations of IL-1, IL-6, and TNF-α (P < 0.01) in groups suffered two-hits were significantly elevated. Group TH + PHC and group TH + ANI notably lessened the concentrations of IL-1, IL-6, and TNF-α in plasma when compared with group TH (IL-1:781.3 ± 145.1 pg/ml; IL-6:723.9 ± 163.9 pg/ml; THF-α: 736.2 ± 177.1 pg/ml; P < 0.05). The concentrations of IL-1 (453.1 ± 193.7 pg/ml), IL-6 (481.2 ± 176.9 pg/ml) and TNF-α (494.2 ± 166.8pg/ml) in plasma in group TH + ANI were notably higher than group TH + PHC (IL-1: 211.3 ± 67.8 pg/ml; IL-6: 273.7 ± 90.1 pg/ml; THFα: 262.4 ± 162.1 pg/ml, P < 0.05). Histological examination The structure of the renal glomeruli and tubuli, proximal and distal convoluted tubes were seen clearly in the sham group (Figure 5A). Severe tubular dilatation and obstruction, glomerulus sclerosis and necrosis, and the development of protein casts were presented in the kidney of the rats in group TH (Figure 5B). Patchy glomeruli and interstitial hemorrhage, tubular epithelium swelling, were found in group TH + PHC (Figure 5C) and group TH + ANI (Figure 5D), the damage severity of renal tissues in these two groups (TH + PHC: 9.8 ± 1.2; TH + ANI:18.1 ± 1.2) were significantly lower than group TH (27.7 ± 1.2, P < 0.05). The mean grade scored of the rats treated with PHC was lower than the rats treated with ANI (P < 0.05). Immunohistochemical detection of ICAM-1 Figure 6 indicates the representative immunohisto-chemical detections of ICAM-1
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African Journal of Pharmacy and Pha
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Editors Sharmilah Pamela Seetulsing
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Electronic submission of manuscript
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Fees and Charges: Authors are requi
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Table of Contents: Volume 6 Number
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African Journal of Pharmacy and Pha
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Minimum inhibitory concentration (M
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Kim et al. 1887 Table 4. Antimicrob
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Klevens RM, Morrison M A, Nadle J,
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Figure 1. Chemical structure of ten
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ng/ml by 4.9 ml blank plasma with 5
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Figure 5. Chromatogram of plasma sp
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Figure 7. Chromatogram of a healthy
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Figure 11. Chromatograms of standar
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Page 31 and 32: Shatoor 1903 Figure 1. The effect o
Page 33 and 34: Heart rate (Beats/min.) 345 330 315
Page 35 and 36: Table 2. Percent of changes in hear
Page 37 and 38: heart rate on coronary flow and car
Page 39 and 40: Urinary tract infections are the mo
Page 41 and 42: Table 1. Study characteristics of i
Page 43 and 44: Table 1. contd. Sun GQ 37 007 Ross
Page 45 and 46: Study or Subgroup Cai SF 2003 Gao H
Page 47 and 48: Study or Subgroup Cai SF 2003 Gao H
Page 49 and 50: cure rate and clinical effective ra
Page 53 and 54: Table 1. The expression of KAI1 and
Page 57 and 58: Figure 2. Typical chromatograms of
Page 59 and 60: Excretion studies Figure 4 shows th
Page 63 and 64: Table 1. Statistical results of the
Page 65 and 66: ethinylestradiol /100 g levonorgest
Page 67 and 68: HO CH 2OH O OH OH OCH 2CH 2 OH Figu
Page 69 and 70: A B Figure 3. Bax positive cells of
Page 73 and 74: Table 1. Summary of specific reacti
Page 75 and 76: Figure 3. Effects of the sap of Jat
Page 79: Figure 1. A schematic diagram showi
Page 83 and 84: Figure 6. Representative photomicro
Page 85 and 86: shock. The features of PHC can expl
Page 87 and 88: Administration of single or repeate
Page 89 and 90: Table 1. Effects of green tea on SO
Page 91 and 92: Ozardali I, Bitiren M, Ali ZK, Zeri
Page 93 and 94: EXPERIMENTAL PROCEDURE Materials an
Page 95 and 96: Scavenging rate (%) Figure 1 Scaven
Page 97 and 98: A D Figure 5 Figure Effects 5. of E
Page 101 and 102: Figure 1. Level-spacing distributio
Page 103 and 104: Number of cases Pattern Shi et al.
Page 107 and 108: sodium was then dissolved in 1000 m
Page 109 and 110: Concentration (ppm) Concentration (
Page 111 and 112: various contagious diseases such as
Page 113 and 114: Table 3. Antibacterial MIC (µg/ml)
Page 115 and 116: Table 5. Contd. 1/5 14.7 ± 0.6 39.
Page 117 and 118: UPCOMING CONFERENCES 6th European C
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