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RISET UNGGULAN DI SETIAP SATKEROUTSTANDING RESEARCH IN EVERY SECTORProfil Balitbangkes19
Pusat Biomedis dan Teknologi Dasar KesehatanCenter for Basic Biomedical and Health TechnologyKarakterisasi Gen HA dari Isolat Virus Influenza A (H5N1) Manusia yangMenginduksi Antibodi Proteksi Silang Terhadap Berbagai Isolat Virus H5N1Characterization Of Gene HA from Human Influenza A (H5n1) Virus IsolatesThat Induces Cross Protection Antibody Against Various H5N1 Virus IsolatesStudi ini dilaksanakan untuk mengetahuiepitop neutralisasi A--E dari virus influenzaA (H5N1). Untuk itu dipilih secaraacak tujuh virus H5N1 dari kelompok virusyang diperoleh sejak tahun 2005—2011. Ketujuh virus tersebut telah berhasil dikulturdan diperbanyak di laboratorium BSL 3di Badan Litbangkes. Protein HA dan NAyang ada pada rantai genetic virus telahberhasil dilakukan sequence full genom.Dari hasil analisis diketahui bahwake tujuh virus tersebut mempunyai homologyyang hampir sama sehingga dipilih satuvirus saja yaitu virus tahun 2007. Virus inidigunakan untuk memvaksinasi kelinci agardiperoleh antibodi terhadap virus InfluenzaA (H5N1). Titer antibodi kelinci tersebutadalah 160 dengan Uji Hambatan Hemagglutinasisetelah 2 minggu divaksinasi. UjiHambatan Hemagglutinasi menggunakanvirus influenza H5N1/2005 RG (provided byCDC Atlanta). Dari hasil ini diketahui bahwaada cross reactivity antara virus tahun 2005dan 2007. Pengujian ini masihperlu dilanjutkandengan virus-virus lainnya.Dari hasil penelitian ini diharapkandapat menunjang program pencegahan infeksivirus influenza A (H5N1) pada manusiaIndonesia, terutama yang berisiko tinggi.This research was done to identifyneutralizationepitop A-E from Influenza Avirus (H5N1 {avian flu}). Seven H5N1 viruseswere randomly selected from virussamplesobtained during2005-2011.TheSeven Virus were all successfully culturedand propagated in a BSL 3 laboratory atNIHRD. HA and NA proteins at virus geneticchain have been successfully being sequencefor the full genome. From the resultof the analysis it is known that the virushas almost similar homology so that onlyone virus was chosen from 2007. This virusused to vaccinate rabbits to obtain antibodiesagainst the virus Influenza A (H5N1).Rabbit antibody titer was 160 with HemagglutinationResistance Test after 2 weeksvaccinated. Hemagglutination ResistanceTest used RG Influenza Virus H5N1/2005(provided by CDC Atlanta). From the resultsit is known that there is cross reactivitybetween the virus from2005 and from2007. Testing still needs to include otherviruses.Result of this research isexpected tocontribute to the development of a preventionprogram for Influenza A (H5N1) Virusfor the Indonesian people, especially forthose at high risk.20 Profil Balitbangkes
Page 1: PROFIL BADAN PENELITIANDAN PENGEMBA
Page 4 and 5: VISI BADAN PENELITIAN DAN PENGEMBAN
Page 6 and 7: Dede Anwar Musadad, SKM, M.KesKepal
Page 8 and 9: Pengendalian Vektor Malaria di Kabu
Page 10 and 11: SEJARAH SINGKATA BRIEF HISTORYProse
Page 12 and 13: Sejak tahun 2010, Struktur Organisa
Page 14 and 15: P2B2 BaturajaZoonoses Research Offi
Page 16 and 17: Herbal Medicine ScientificationSain
Page 18 and 19: RISET KESEHATAN SKALA NASIONALHEALT
Page 20 and 21: angan ruta dan keterangan anggota r
Page 22 and 23: Asosiasi Rumah Sakit Vertikal Indon
Page 24 and 25: Kalimantan Selatan, Schistosomiasis
Page 26 and 27: SAINTIFIKASI JAMUJAMOE SCIENTIFICAT
Page 30 and 31: Pusat Biomedis dan Teknologi Dasar
Page 32 and 33: MTB bacteria from the entirestudy s
Page 34 and 35: tan minyak. Isolat galaktomananyang
Page 36 and 37: mudian diberikan kepada panelis di
Page 38 and 39: ditemukan penderita cacing tambang
Page 40 and 41: secara nyata oleh masyarakat. Berda
Page 42 and 43: yang berkualitas; meningkatkan sist
Page 44 and 45: Riset operasional ini akan mengemba
Page 46 and 47: Balai Litbang Biomedis PapuaBiomedi
Page 48 and 49: nyebabkan keturunannya tidak dapatm
Page 50 and 51: sanaan kegiatan dilakukan melalui d
Page 52 and 53: Balai Litbang P2B2 DonggalaZoonoses
Page 54 and 55: Balai Litbang P2B2 DonggalaZoonoses
Page 56 and 57: Balai Litbang P2B2 BanjarnegaraZoon
Page 58 and 59: dinasi mengenai kecacingan dengan p
Page 60 and 61: Loka Litbang P2B2 BaturajaZoonoses
Page 62 and 63: Loka Litbang WaikabubakZoonoses Res
Page 64 and 65: SUMBER DAYA MANUSIAHUMAN RESOURCESB
Page 66 and 67: KEPAKARANEXPERTISEIlmu Kedokteran (
Page 68 and 69: SembilanSatuan Kerja (Satker) Badan
Page 70 and 71: mites) and research Seroepidemiolog
Page 72 and 73: gesic use white mice, white rats Ac
Page 74 and 75: KLINIKCLINIC1. Klinik GiziNutrition
Page 76 and 77: WISATA ILMIAHSCIENTIFIC TOUR1. Teat
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. Kebun KarangpandanKarangpandan Ga
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4. Perpustakaan Balai Besar P2B2TOO
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JURNALJOURNAL1. Jurnal Terakreditas
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KERJASAMA DAN JEJARINGCOOPERATION A
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the National Committee for Health R
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for pesticide evaluations); Interna
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the field of healthUPF Nanggroe Ace
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12.13.14.15.16.17.1.2.3.4.5.6.7.8.9
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Peningkatan Sistem Registrasi Kemat
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9Epidemilogi Penyakit P2B2, Aspek P
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Studi Epidemiologi KLB Penyakit Tul
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drh. M. Wien Winarno, Kes11. Increa
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13. Intervention studies tradition
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albopictus in relation to the incid
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In 20118. Epidemiology of filariasi
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TIM PENYUSUNPENGARAHDr. dr. Trihono
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