12.07.2015 Views

Thema: Diabetes mellitus en infectieziekten Het ... - NVMM

Thema: Diabetes mellitus en infectieziekten Het ... - NVMM

Thema: Diabetes mellitus en infectieziekten Het ... - NVMM

SHOW MORE
SHOW LESS
  • No tags were found...

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

de H275Y-substitutie die zich gemakkelijk verspreidt.Dit gebeurde in 2007/08 met het to<strong>en</strong>malige A(H1N1)-seizo<strong>en</strong>sinflu<strong>en</strong>zavirus. Binn<strong>en</strong> e<strong>en</strong> jaar heeft to<strong>en</strong> ditgemuteerde virus wereldwijd het oseltamivirgevoeligeA(H1N1)-virus bijna compleet verdrong<strong>en</strong>.SummaryThe influ<strong>en</strong>za epidemic of the 2011/12 season was small,short and late. Most of the causative viruses were ofsubtype A(H3), the phylog<strong>en</strong>etic lineage B/Yamagata/16/88was dominant among the B viruses, and subtype A(H1N1)pdm09 was rarely detected.Since the 2010/11 season, in g<strong>en</strong>eral no significant antig<strong>en</strong>icdrift has occurred in any of the four circulating (sub)types/lineages and the vaccine compon<strong>en</strong>ts matched wellwith the circulating viruses. However, during the season,significantly low reactive A(H3) viruses appeared, indicatingan antig<strong>en</strong>ic vaccine mismatch for this subtype. For the2012/13 season, the World Health Organisation (WHO)recomm<strong>en</strong>ded inclusion of A/California/7/09-like strainsfor A(H1N1)pdm09, A/Victoria/361/11-like strains forA(H3N2) and B/Wisconsin/1/10-like strains from the B/Yamagata/16/88 lineage for B. For the first time, WHO alsoallowed the use of a B/Brisbane/60/08-like strain from theB/Victoria/2/87-lineage in a trival<strong>en</strong>t vaccine, or both Bviruses in a quadrival<strong>en</strong>t vaccine. A(H1N1)pdm09-virusesshowing highly reduced s<strong>en</strong>sitivity to oseltamivir due tothe H275Y amino acid substitution in the neuraminidase,were detected in two pati<strong>en</strong>ts, who had not be<strong>en</strong> treatedwith oseltamivir.Dankbetuiging<strong>en</strong>Ook in het seizo<strong>en</strong> 2011/12 was de influ<strong>en</strong>zasurveillancein Nederland niet mogelijk geweest zonder de bereidheidvan de hoofd<strong>en</strong> van de diagnostische ziek<strong>en</strong>huislaboratoriainflu<strong>en</strong>zavirusstamm<strong>en</strong> of klinische monsters waarin doorh<strong>en</strong> influ<strong>en</strong>zavirus was aangetoond, naar het NIC op testur<strong>en</strong>. De bijdrag<strong>en</strong> van de peilstationhuisarts<strong>en</strong> van hetNIVEL war<strong>en</strong> ev<strong>en</strong>e<strong>en</strong>s ess<strong>en</strong>tieel voor deze surveillance.De auteurs dank<strong>en</strong> R. van Beek <strong>en</strong> H. de Gruyter (ErasmusMC), M. Bagheri, T. Marzec, S. J<strong>en</strong>ny, P. Overduin <strong>en</strong>M.A. de Lange (RIVM), <strong>en</strong> M. Heshusius-van Val<strong>en</strong><strong>en</strong> P. t<strong>en</strong> Ve<strong>en</strong> (NIVEL) voor de uitstek<strong>en</strong>de technischeondersteuning.The authors gratefully acknowledge the g<strong>en</strong>erous giftof influ<strong>en</strong>za refer<strong>en</strong>ce viruses and antisera from Dr. J.McCauley of the World Influ<strong>en</strong>za C<strong>en</strong>tre in London.Pot<strong>en</strong>tieel belang<strong>en</strong>conflict: J.C. de Jong, G.F. Rimmelzwaan<strong>en</strong> A.D.M.E. Osterhaus zijn fulltime of parttimemedewerkers van ViroClinics Biosci<strong>en</strong>ces BV, e<strong>en</strong> ErasmusMC spin-out die contractresearch uitvoert voor de farmaceutischeindustrie. De andere auteurs meldd<strong>en</strong> ge<strong>en</strong>mogelijk belang<strong>en</strong>conflict.Refer<strong>en</strong>ties1. Donker GA. Continue Morbiditeits Registratie peilstations Nederland2010. Utrecht: NIVEL, 2011. 183 p; www.nivel.nl/peilstations.2. Meijer A, Jonges M, Abbink F, Ang W, van Beek J, Beersma M, et al.Oseltamivir-resistant pandemic A(H1N1) 2009 influ<strong>en</strong>za viruses detectedthrough <strong>en</strong>hanced surveillance in the Netherlands, 2009-2010. AntiviralRes. 2011;92:81-9.3. Donker GA, Gravestein J. De beste tijd voor griepvaccinatie. Huisarts &Wet<strong>en</strong>schap. 2007;50:41.4. WHO. Recomm<strong>en</strong>ded composition of influ<strong>en</strong>za virus vaccines for usein the 2012-2013 northern hemisphere influ<strong>en</strong>za season. Wkly EpidemiolRec. 2012;87(10):83-95.5. De Jong JC, de Ronde-Verloop FM, Ve<strong>en</strong><strong>en</strong>daal-van Herk TM, Weijers TF,Bijlsma K, Osterhaus ADME. Antig<strong>en</strong>ic heterog<strong>en</strong>eity within influ<strong>en</strong>zaA(H3N2) virus strains. Bull WHO. 1988;66:47-55.6. De Jong JC, Donker GA, Meijer A, van der Hoek W, Rimmelzwaan GF,Osterhaus ADME. <strong>Het</strong> influ<strong>en</strong>zaseizo<strong>en</strong> 2010/11 in Nederland: hetnieuwe A(H1N1)-virus van 2009 blijft actief. Ned Tijdschr Med Microbiol.2011;19:21-27.7. Lin YP, Gregory V, Collins P, Kloess J, Wharton S, Cattle N, Lack<strong>en</strong>by A,Daniels R, Hay A. Neuraminidase receptor-binding variants of humaninflu<strong>en</strong>za A(H3N2) viruses resulting from substitution of aspartic acid 151in the catalytic site: a role in virus attachm<strong>en</strong>t? J Virol. 2010;84:6769-81.8. Meijer A, Jonges M, van Beek P, Swaan C, Osterhaus A, Daniels R, HurtA, Koopmans M. Oseltamivir-resistant influ<strong>en</strong>za A(H1N1)pdm09 virusin Dutch travellers returning from Spain, August 2012. Euro Surveill.2012;6:17(36). pii: 20266.Ned Tijdschr Med Microbiol 2012;20:nr4148

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!