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Implementing food-based dietary guidelines for - United Nations ...

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Establishing nutrient intake values<br />

each person in a population group. With the growing<br />

problem of obesity and overweight, it is more difficult<br />

to determine what the mean energy intake of a group<br />

should be to meet the requirements of all members of<br />

the group, yet not result in overconsumption by some.<br />

Unlike the use of average population intakes <strong>for</strong> nutrients<br />

in apparently healthy populations as surrogates <strong>for</strong><br />

an INL x where dose–response data are not available,<br />

average energy intakes cannot be used, as most populations<br />

in both developed and developing countries<br />

are now experiencing adverse effects associated with<br />

excess consumption of energy, inadequate physical<br />

activity, or both.<br />

Methods of estimating energy requirements<br />

Similar to nutrients, energy requirements measured<br />

in individuals with similar characteristics, such as<br />

age, body size, sex, and physical activity levels, vary;<br />

the variation seen in observed requirements assumes<br />

a normal distribution. When energy expenditure<br />

over time (e.g., 2 to 3 weeks) is measured carefully<br />

in a sample of individuals whose characteristics are<br />

known, it is possible to develop estimates of energy<br />

requirements <strong>for</strong> the group, along with a measure of<br />

the variance in those requirements among the individuals<br />

in the sample. These requirement distributions<br />

have been used to predict the requirements <strong>for</strong> other<br />

individuals with similar characteristics. One of the<br />

advances in the ability to develop good predictions of<br />

energy requirements is the ability now to use tracer<br />

methodology, such as doubly labeled water, to obtain<br />

independent estimates of energy expenditure without<br />

perturbing the environment of the individual [10].<br />

Older methods estimated expenditure indirectly (e.g.,<br />

metabolic hoods) or estimated <strong>food</strong> intake and derived<br />

the amount of energy consumed, equating it with the<br />

amount expended.<br />

Components of energy requirements<br />

As outlined in the definition of energy requirements,<br />

the energy required <strong>for</strong> five general components makes<br />

up the total human energy requirement: basal metabolism,<br />

metabolic response to <strong>food</strong>, physical activity,<br />

growth, and needs during pregnancy and lactation.<br />

Early studies of energy requirements, in which the<br />

method used to estimate energy expenditure itself<br />

influenced the energy requirement, often involved<br />

estimating each of these individually and summing<br />

the total to get the total energy required. With the<br />

advent of doubly labeled water, prediction equations<br />

that take into account all of these energy components<br />

have been developed. Recently, doubly labeled water<br />

has been used as well to validate other methods to estimate<br />

energy requirements that are less expensive and<br />

more adaptable to different settings, such as heart-rate<br />

monitoring [24].<br />

S47<br />

Equations that are derived from these data depend<br />

on the accuracy of the method employed and the extent<br />

to which variables in energy expenditure are included<br />

as identified factors that influence energy requirements.<br />

Sex, age, body weight (or body mass index<br />

[BMI]), and level and types of physical activity have<br />

been found to have the greatest effect on total energy<br />

requirements [10, 24].<br />

Prediction equations now available are useful as<br />

initial estimates of energy requirements <strong>for</strong> other<br />

similar population groups, assuming that the in<strong>for</strong>mation<br />

about the population subgroup (i.e., age, body<br />

weight [BMI], and activity level) is known. Prediction<br />

(regression) equations developed to date have<br />

estimates of variation as well, and these provide the<br />

ranges (representing expected variation) that would<br />

be predicted in actual requirements as compared with<br />

the point estimates obtained from the regression equations<br />

[10, 24].<br />

Use of prediction equations as NIVs<br />

Tables have been constructed that translate the prediction<br />

equations into estimates of energy requirements<br />

by age, sex, physical activity, and/or body weight;<br />

these can be applied to other population groups after<br />

adjustment <strong>for</strong> known differences in physical activity,<br />

body size, and other variables that may not be included<br />

in the tables. In<strong>for</strong>mation on how best to use the data<br />

and in<strong>for</strong>mation is provided in the reports [10, 24] that<br />

have developed the prediction equations and should be<br />

used as a starting point <strong>for</strong> group-specific estimates of<br />

energy requirements.<br />

Summary<br />

In establishing nutrient intake values (NIVs) to meet<br />

requirements (and usually <strong>for</strong> excess intakes), it is<br />

important to specify the criterion or indicator of adequacy<br />

or excess that is selected and to be transparent in<br />

the dataset used to set the NIV. For almost all nutrients<br />

studied to date, there exists a continuum of definable<br />

functions, most of which are impaired at low levels of<br />

intake, whereas at high levels of intake all appear to<br />

function normally or to be within the normal range.<br />

Choice of the indicator will dictate the amount of the<br />

nutrient that meets an individual’s requirement, as<br />

defined by that indicator. Datasets from dose–response<br />

studies in which nutrients at multiple levels (at least<br />

three) are given to the same individuals and in which at<br />

least one level results in measured abnormal responses<br />

or functions are important to serve as the basis <strong>for</strong><br />

determining average nutrient requirements (ANRs).<br />

Of equal if not greater importance is the distribution<br />

of requirements in a group; variation in requirements<br />

can be due to differences in metabolism, but also to<br />

differences in environment and diet. A key component

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