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BIMM118
• Advantages:
– 100% “Absorption”
Parenteral Drug Administration
– Drug enters general circulation without hepatic passage -->
No first-pass hepatic elimination
– Better bioavailability of hydrophilic drugs
• Bioavailability/Speed of Absorption
– Intravenous (i.v.): Fastest (infusions; cardio-vascular drugs)
– Intramuscular (i.m.): Medium (anti-inflammatory; antibiotics)
– Subcutaneous (s.c.): Slowest (vaccines; insulin; depot contraceptives)