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p-Tert-Butylphenol - UNEP Chemicals

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OECD SIDS P-TERT-BUTYLPHENOL<br />

Classification: Highly corrosive (causes severe burns) [ ];<br />

Corrosive (causes burns) [ ]; Irritating [ ]; Not irritating [ ]<br />

Method: Standard Draize test<br />

GLP: Yes [ ] No [ ] ? [X]<br />

Test substance: purity: unknown<br />

Remarks: Exposure period: 500 mg/24 hours<br />

Reference: Prehled Prumyslove Toxikologie: 1986<br />

(c)<br />

Species/strain: Rabbit<br />

Results: Highly corrosive [ ]; Corrosive [ ]; Highly irritating [ ];<br />

Irritating [ ]; Moderate irritating [X]; Slightly irritating [ ];<br />

Not irritating [ ] *See Remarks<br />

Classification: Highly corrosive (causes severe burns) [ ];<br />

Corrosive (causes burns) [ ]; Irritating [ ]; Not irritating [ ]<br />

Method: Other<br />

GLP: Yes [ ] No [X] ? [ ]<br />

Test substance: purity: unknown<br />

Remarks: Uncovered application of 0.01 ml on the rabbit belly.<br />

Irritation was induced, and the injury grade was described as 6 of 10 in<br />

IUDLID Database.<br />

Reference: Smyth et al.: 1969<br />

(d)<br />

Species/strain: Rabbit<br />

Results: Highly corrosive [ ]; Corrosive [ ]; Highly irritating [ ];<br />

Irritating [X]; Moderate irritating [ ]; Slightly irritating [ ];<br />

Not irritating [ ] *See Remarks<br />

Classification: Highly corrosive (causes severe burns) [ ];<br />

Corrosive (causes burns) [ ]; Irritating [ ]; Not irritating [ ]<br />

Method: OECD Guideline No. 404 "Acute Dermal Irritation/Corrosion"<br />

GLP: Yes [ ] No [X] ? [ ]<br />

Test substance: purity: unknown<br />

Remarks: Irritation was induced, but the severity was not described in IUCLID<br />

Database.<br />

Reference: Huels-Bericht: 1985<br />

(e)<br />

Species/strain: Rabbit<br />

Results: Highly corrosive [ ]; Corrosive [X]; Highly irritating [ ];<br />

Irritating [ ]; Moderate irritating [ ]; Slightly irritating [ ];<br />

Not irritating [ ] *See Remarks<br />

Classification: Highly corrosive (causes severe burns) [ ];<br />

Corrosive (causes burns) [ ]; Irritating [ ]; Not irritating [ ]<br />

Method: Other (BASF test)<br />

GLP: Yes [ ] No [X] ? [ ]<br />

Test substance: purity: unknown<br />

Remarks: Corrosion was induced, but the severity was not described in IUCLD<br />

Database.<br />

Reference: BASF: 1971<br />

(f)<br />

Species/strain: Rabbit<br />

Results: Highly corrosive [ ]; Corrosive [ ]; Highly irritating [ ];<br />

<strong>UNEP</strong> Publications 107

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