The EffĘcts of In Partial 3ėĄLfil1n€nt of Tle B€qüireûents for Eh ...

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U) Ld Ø Z o o_ (n tJ t J F o F- [_] - rotol Lovcr Prcsrì l..1ITl- Rcinf otcod Le ver Press F'ZI] -r'enotty count flflffi - rrio r aborr counÌ DCA WITH CORR ECTIO ¡]AL INPUl SESSIONS i5 - 19 2A-?4 25-29 TION REST PERIOD (/) ^^L (Ì: o co J s tt- t5' _J g o F
I'igure 46. Effects of 2.5eg/r'kg d-anphetamine on runúing rheel actiïj.ty in tro¡tal,fronta1 op€rated {:ortrolrand no¡mal ¡ats. Exper ioenta]. session started imnediately aft€r :ntrap€ritonial injectåcn of drüg. llunbêr of rotatlôrs !rêre coüDt€d at '10miåut€ interval fo¡ 100 nioutes. Notê the second p€ak exhibited by fxoDtal aninêls alur lng the second half cf the session. 132
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U¡I IV EIì SIT T Og }lANTTI]BII T
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To Dr, Terrence p. Hogan, r4rhose d
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J. gÉcJrtyr€, D¡. V. fia¡rl.j-
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4851RÀCT îJsieg the ccncêpÈ j-n
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ChaFter 1 nêvies of l,i t€ ra tu
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espons€ perfcrmaîce {Battig ,tos
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tail cf thê nuclèus. Kenp speciti
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espons€ lia various experimentê1
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iûemory of t Le di¡ecticnal cr€
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Test Açparatus. ]n the :rbait€dt
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sho!¡eC that (1) botà bilat.€ra
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aJìd prefrontal; Éost.erior caud
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oo.re plecise descríptj-cn cf tiì
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contrary to Èhê seco:ìd 1ësicn.
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enalns. Witä proLcnged stirula¿io
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Effects Õf tbe stiflìulaticn .n t
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vioural a:ìd êlect_rophysiolcgica
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ately iollcw:.ng ti¡û€ cut of t
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they i¡¡bi.b!t dif f erent behavi
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dê1ayêd respÕ]]se ¡aìd t€epo
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subjec t s. üiles { t96q) rê}ûrt
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¡ent in th task. Th€ se"êrj-t.y
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fashioD. Ècberts stat€d tbat tbe
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ather then thÐ reflex apparatus of
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perforn certaiD tasks. IhÈf shô*
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t_EÀ Dff ¡ìÞ llr TBE TIi TS SlT
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Frgura 2. À schenìatic diagram Ð
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the latter flill- carse a i¡crease
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a1l Ss {Hhj.ttiert Orx,1962), follo
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tion , a iailu¡e to rêspond durin
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. BE,HAVIORAL G ) MEASURE _ _ ___J
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¡xp€riaental aesign: the ¡€la
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Èxpêrieê¡tal sessicn conpris€
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PSOCTDIJS! A. Delayed Conditj_on€
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Du.ring surgêrl, a scalp vas used
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a1 prûcedures lierê doûe j.r¡ t
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thê last pre-operativ€ day aåd
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considë¡aticì. .fôr a rdor€ d
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HhÊn thê sìlFerimposed .I/0 coDr
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actiyity colr:tter êtc, Ss j-! the
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Figure 4, t{ean of the totaL nueber
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Sigurs 5. l{€an of a) total l€v
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Íigure 6. ïhe n€an Ëespc¡s€
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3ì-gure ?. ThË d.if ferÈ¡ce pto
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figurê 8. Þ- plot of the H CD on
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Figurè 9" the phese p].ane repr€
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Yigure 10, The phase diagran Õf be
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-lP coO DP/DT i.60 (t-- -c I (t o -
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.a r O< co,
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.00 16 .00 B l. 00 T ( ÞAYJ
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î ) r(, tlJ I F = U) J I t rd o ul
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last t'¡o ti$ê blocks. These resu
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shorte¡ 1at€nciês ,the trajêct
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(n td (n z. o o_ U) td É. J t-o F
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CAUDATE OPERATED CONTROL N=5 :::[ -
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Þro; - prl d. 00 0. 20 0. q0 -t C)
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acLti+l',àn af t/o & rest svrger¡
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ç ô F
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_1 3ã coF
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a F Ë .9. ô DPlDT 0. ûrl o) -J -
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-0.12 -0.10 -0. 0B DPlDT -0. 06 -0.
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oB jo- 10/¿c
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perrfìanent-l'y êtaxicrthough t¡
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êspo¡sÈ of the slstem flas Colì
Page 130 and 131: ¡igure 24. l{ealì of tatal nünb
Page 132 and 133: figure 25. The mêan of a) totâl l
Page 134 and 135: Figure 26. The ean respors€ laten
Page 136 and 137: Figure 2?. Th€. differ€ncê Fl-
Page 138: figurë 28. P Flot Õf Ð-1 syst€
Page 141 and 142: ',' O< O¿I æF
Page 143 and 144: 16'r.00 2t..00 url.00 I'i. 00 T ( D
Page 145 and 146: 0uaJ o/1 {î foÍaÚ'¡z-\ I .sJ ¿
Page 147 and 148: h0'0- IA/ ¿C
Page 149 and 150: .n,vd, oJ t/o I, 1.68 P
Page 151 and 152: LAST DAY ON DCA €-o CEREBELLAR SS
Page 153 and 154: ìu$ber of rei¡forc€d 1€ver F
Page 155 and 156: figure 35. Beans o'f altst-al lever
Page 157 and 158: fj-guEê 36. Thê ¡Þêa¡¡ respo
Page 159 and 160: Figurê 37. P{0}-P{T) plct cf !-r c
Page 161 and 162: Figur-- 38. P plct of ¡-I C an DC
Page 163 and 164: Fígure 39 P flot of t-.tr c group
Page 165 and 166: Figure 40 P plot of D-I c grcup ait
Page 167 and 168: Pigure 41. Phase repres€ìtation
Page 169 and 170: figure 42. Phase diagraB Ð{ t-f c
Page 171 and 172: figure .43. Phasè diagram of Ð-I
Page 173 and 174: GÊOüP V the group sÍtå bilatera
Page 175 and 176: Pr€-operat j,qely the r€sFo¡se
Page 177 and 178: FiguEê 49. Aciívity levêl of fro
Page 179: figure 45. geans of total- I}r bÊr
Page 183 and 184: Figure 4?. Þlean resporse låt€n
Page 185 and 186: Figure ¡¡8. Ðiffer+nce plot I {0
Page 187 and 188: Figüre 49. F pl-ot of th€ frcrta
Page 189 and 190: 'rigure 50" Phasè pla¡ìe reFrese
Page 191 and 192: figure 51. P plot cf frÕntâl €y
Page 193 and 194: figure 52. P plot of Érontal syst
Page 195 and 196: figure 53. Phas€ dLagrâm .f lron
Page 197 and 198: figure 54, lesioning. focüs around
Page 199 and 200: gigure 55. EltinctiÕn curv€s of
Page 201 and 202: GRoUP v.r the group *ith bil-at€r
Page 203 and 204: Sj.gure 56" The neans of a) tctaL l
Page 205 and 206: Figure 5?. ¡leân r€sponse lat
Page 207 and 208: Figurê 58. titferÈnce plct of the
Page 209 and 210: FiguEe 59. P çlot of the frontal s
Page 211 and 212: ¡'igu¡e 60. F plot cf the troãta
Page 213: Figlrre 61. ? plct of the systeû s
Page 216 and 217: -!l: _l O ne tnt 0. 00
Page 218 and 219: ¿ 09'1 I P O n) I P O F tl rcl 1\
Page 221 and 222: cRoup vIT t*e qxoup ¡{ith bilãt
Page 223 and 224: initial ¡egât:i-ve relative èrro
Page 225 and 226: Y I LIJ II-þ ö P CD control n-3 m
Page 227 and 228: (n L] (n ;Z o o_ (Ð Ld r J F o F [
Page 229 and 230: 1 () Ld 2 No Coireclionol Input C)
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D I 'T: I - f tlJ 5-00 P r0) 3. 00
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Tigure 68, P f lo+- of P CD systen
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liEurë 59. P pl-ct oÍ P CD systë
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figutre 70. thas€ plar¡e rep.res
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figurê ?1. thase d.iagraûr e1èct
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gigurê ?2. phase d j.agxam of P C
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Figure 73. trxtj.!ìction cqrÌes o
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GROI¡P VIII the group ljith shan l
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predomi.natj-ng forc: Õf erti.ncti
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U) l! U) z o o- U) ¡.rJ E. J F o F
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t Þ c õ' J g (D
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_ P (T] 0-20 0.40 P (0) c0. 00
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Fågure ?8. P llût of P cX C pcior
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fÍgure 79. P plot cf P cD c subsê
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Íigure 80" Phase dj-agra! cf P CÐ
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yígure 81. ?hâs€ diagran of p C
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GAOü.P VIITI the norcal control gr
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p].ots of the N group bêfcr€ and
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figure 84. th€ seans af al cèal
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Figure 85. T!€ úean resçcnsê l
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figure 86, The diff€Ë€nc€ pl
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giEure 87. P p1Ðt af the ncrnaì s
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FigurÐ 88. I plot of the Bor¡ìal
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Figure 89. .P Flot of the rìornal
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Figure 90. Phase diagran of the nor
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figurê 9'l . Phesê ðiagraB ci th
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Figüre 92. Phase plaae represenr-a
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N TS ü1,Ì S: THB IiISTOI.OGÏCÀL
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Th€ s€ct j-cns of the corpus c
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Du€ tc the closeness of thê l*si
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quadrant j.n th. right heaisçh€x
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the lesianing cuErent prcdüceü a
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figure 93. Ðiagrannìatj.c rÊpr+s
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Ðj-agra$ Ð. À diagran ct a braiq
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Ðiagram c.À diagran Ðf a brain s
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Diagran 8. Ðiagraus cf brai¡ spec
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Ðiagran À. A diagEar!ì af a bila
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'1:' t" rat # 85, sJ-ide -/ Z,area
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at ,# 51 , slide 1J point of entry
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_. \- I ¡ s lid.e ;f 14 slide # 15
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Ea-. ¡at # 81, slide t' 4 rat ,.f
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tu¡€s. Co¡ìsequently àher€
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Ï/Ð ccntf,c1. Iio*eveE,i-h€ beh
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voluntary u¡skil-I€d movenênts
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nê¡nely tàê ahility -tro dêIay
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The post-oFerative testíng sèssio
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a!. d Erocks al-l- i.np1i*d th€ e
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REFTASNCES âtlEian, E.Ð. After€
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Inhibitcry ¡esponses to Lasal- gan
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disordârs ct mcvement.I.cndo¡:Oxf
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çross,C,Ð. Ccnpar j.sc¡ Ði thê
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llarren E AN€rt{€ds.},T}€ Frc
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of T €C€At ne sì or y a n å m
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Nautard.J.¡l . Sc ìê etfereat cc
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York: Ap FL€tcn-C€ntury cEsf ts
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Toaonicr!Ì. :¡tlo. to nonlirìear
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ÀPFTNDI T 1
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tla lasz u se d the e.lastic spring
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index is conput€d âad fêd ¡ack
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tendencj.es cf a freqre¡cy distrib
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the un knar¿n €q uaiio¡s. l{he
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statistical êstimaticr, !chich doe
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¿n9 of the bêhavioural systens lo
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nois€s/cont an anants. ovÊraIl.,
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CEREEEI-LUM IVlOTOR ÜCRTEX CONTROL
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