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The EffĘcts of In Partial 3ėĄLfil1n€nt of Tle B€qüireûents for Eh ...

The EffĘcts of In Partial 3ėĄLfil1n€nt of Tle B€qüireûents for Eh ...

The EffĘcts of In Partial 3ėĄLfil1n€nt of Tle B€qüireûents for Eh ...

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j.tìhj'bitcry F.rocesses Þanj.fêsted both by itebavioural<br />

chang€s {eg. fron aL€rtlìess t. drosiDess and sleep ) and<br />

by the occu¡reüce cf rtcaud.at€-sFindlâsr iü t.he el-eciro-<br />

g.rån, ¡rhj.ch is a train <strong>of</strong> high voltage, rhyth,nical<br />

osciLlatirrl, lasting 3 s€c. j-n aturati_on, uith a latency<br />

<strong>of</strong> 150 - 200 msec. ). Bottr the -behavioural changes and<br />

the êl€ctrical recordi-ngs cou]-d b€ disinhÍbited by ¡ove1<br />

stiúulation. 4Õ cats s€re used i¡ acute and clironic<br />

èxpçri$€Ilts to study the ccrtj_cal Loci ûf the caudle-<br />

spind.le {BuchwaId et al, 19É1a} . !tith a loH intêasity<br />

singlê shcck, 0.01 nsec. duration, at 5 sec interval, <strong>of</strong><br />

the caudate nucleus, ,spiûaile bursts ïèxe picked fron<br />

seïeraL cortical aÐd subcortical- sit€s. <strong>The</strong> nost Frcminent-<br />

place <strong>for</strong> sFi¡illÊ actieÍty ís the ipsilateral<br />

precxuciate {antexi-ôr sigmoì-d gyrus} regÍos <strong>of</strong> the<br />

cortex" It can also he obt.ai.neå fron contralateral<br />

ant€rior signci.d gyrus, bcth pcsterior g1ri, nost <strong>of</strong> tìÊ<br />

thalanus, g].obus patliilus, contralatèral caudat€ nucleus,<br />

en tope¿uncü laxis, and septun. <strong>The</strong> cat¡datë spindìê is<br />

elicitêd at a r€gue¡cï <strong>of</strong> 1C-12 $z and can be obtained<br />

fron resting or sleeping aDinals and in prepâTatio[s<br />

ex hibiti.ng r€ lati.vêly sl"c* rhythmical elect¡ocortíco-<br />

grans. trt is thüs antagûnisti.c to f unctioni-Dg <strong>of</strong> th€<br />

ceûtra.]- arcusal systen. <strong>In</strong> retation to rther brain<br />

arÊâs, the authors sho*ed that €Lë {trocoagulat ion <strong>of</strong> the<br />

tha-¡-anic ¡ucleüs "e¡tra"l-is anterior ipsilateral to th€<br />

sj-t,e <strong>of</strong> caudate stinllLatåc¡r sutfresses {ca ud.atä -spind]-ê sfl<br />

at thç ipsilateral cortex but contralatêtal spiadling<br />

23

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