The EffĘcts of In Partial 3ėĄLfil1n€nt of Tle B€qüireûents for Eh ...

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neither a d€lay nÐr a screê¡¡ A Feanut uas pl-aced in thÊ left oE rj"ght. tcodr,rel-l" Thèn tloth {el1s sê.e cove rêd lrith nêutrô.1-gray cårdboard plaques ânC the aninal ras aIlo!¡Èd to nakê ê rloice. lr] Fhas€ If, thêre ïas nc def,ay but a scr€ê¡ì rras inttoduc€d an4 1rì phase IIT, both screen and d€lay $.:e int.rcduc€d. Delay eas graduall.y increased f,rcm t!¡o to ten sêconds j-n steps ôf 1 second.s. Bilateral lesi-on of, do1:so:_ateral t.ont.a1 cortex a¡d of the h€ad of tle caudate nrclêus bcth protluced impairn€nt on th€ tso tesÈs erFloyed, ¡ut the nag¡itudê ûf öeficit ¡,as gr€at€r rith t.hè f ¡ontal grct¡F " Tn addj-tion têsts oTl the àl"tertation in thê autonatic appaEatËs ¡rerê nost severel-y inFair€d, an etfêct lrlj.ch th€ authÐrs attrit¡uted to th€ rèlativê}y sfiall€r .cùnìber cf stimulus cues iñ t.he test situatioü. Àhsioi:'aE tr€¡d of results as observÈd in a go-no-go dåscriûination task {Battig et al-, .l962 ), In the 1962 stlrdy th.e aut.bors studieä the ccrûparat ivê €ffects of bilateral frontaL ând of the head of caudate ûucleüs l€sicf¡ on I{CTA gð-no-go aEdi.torT discrininatio¡ j.rì adult ràesus ûo¡keys, ï,ith a vi_e}I to find oirt if di.scxj-Einatioa alrl d.+l-ayçd response wer€ ãìediated via the sane ¡êurâ1 m€chanisn. I¡ th€ testing sitllaticã 5s fi€r€ present€d ìJith a Fa*€j-tivç 1000 I{z tone or a negatj. v€ uhite ncise. The subj€ct üas traj.neC to rêach for ¡e*ard coverêal undêr a 3 1n. square gray cardbÐard *rithin 5 sec. or: to rèfrai! fron reachiftg lrith prêseÞtation of the negat.ive CS. O:r colour dÍscriminatioû, reil sígnalëd revaEd r¡hj.1€ green signa].€d $ot-rèwärd, Thê res¡rlts 15
sho!¡eC that (1) botà bilat.€raL abl-ation Õf the dorsotät- er äl- prefrontal cort€x and cf, thê head of the câüdat€ nucleus imFaj-rcd D8 and discri-mj.¡ation tasks; and {21 the fûrm€Ë type of lesicn prcdur€d greater inpairnent, ßisiÌkin 11962, l9ó4) studlêd effects cf orbital frol}tal a!C .Lateral lesicns on visual and aüd:_tory iliscrirj.natioa, l€ar!ìi.ng s€t, discrinj_naÈion reversaln one-trial leaE¡inq and spatial r€v€!sal, Theif results shoved that th. perf,crnance €f th€ lateraL f ro¡ta.l grrup vas b€tt.€r than that c.f th€ o¡bital group on all tasks excep! cn .ÐR, althougþ perfcr ance deficÍts Here detectrd. for both gEoups. Thè aBthcr postulated that fro¿tal" 1êsi.on prcduced Loss Õf act inbil¡it.ion. Th€ great€r iepairüent produceC by th€ late¡al lesion *¡as an €ffect of bot.h Í,ea¡
Page 1 and 2: U¡I IV EIì SIT T Og }lANTTI]BII T
Page 3 and 4: To Dr, Terrence p. Hogan, r4rhose d
Page 5 and 6: J. gÉcJrtyr€, D¡. V. fia¡rl.j-
Page 7 and 8: 4851RÀCT îJsieg the ccncêpÈ j-n
Page 9 and 10: ChaFter 1 nêvies of l,i t€ ra tu
Page 11 and 12: espons€ perfcrmaîce {Battig ,tos
Page 13 and 14: tail cf thê nuclèus. Kenp speciti
Page 15 and 16: espons€ lia various experimentê1
Page 17 and 18: iûemory of t Le di¡ecticnal cr€
Page 19: Test Açparatus. ]n the :rbait€dt
Page 23 and 24: aJìd prefrontal; Éost.erior caud
Page 25 and 26: oo.re plecise descríptj-cn cf tiì
Page 27 and 28: contrary to Èhê seco:ìd 1ësicn.
Page 29 and 30: enalns. Witä proLcnged stirula¿io
Page 31 and 32: Effects Õf tbe stiflìulaticn .n t
Page 33 and 34: vioural a:ìd êlect_rophysiolcgica
Page 35 and 36: ately iollcw:.ng ti¡û€ cut of t
Page 37 and 38: they i¡¡bi.b!t dif f erent behavi
Page 39 and 40: dê1ayêd respÕ]]se ¡aìd t€epo
Page 41 and 42: subjec t s. üiles { t96q) rê}ûrt
Page 43 and 44: ¡ent in th task. Th€ se"êrj-t.y
Page 45 and 46: fashioD. Ècberts stat€d tbat tbe
Page 47 and 48: ather then thÐ reflex apparatus of
Page 49 and 50: perforn certaiD tasks. IhÈf shô*
Page 51 and 52: t_EÀ Dff ¡ìÞ llr TBE TIi TS SlT
Page 53 and 54: Frgura 2. À schenìatic diagram Ð
Page 55 and 56: the latter flill- carse a i¡crease
Page 57 and 58: a1l Ss {Hhj.ttiert Orx,1962), follo
Page 59 and 60: tion , a iailu¡e to rêspond durin
Page 61 and 62: . BE,HAVIORAL G ) MEASURE _ _ ___J
Page 63 and 64: ¡xp€riaental aesign: the ¡€la
Page 65 and 66: Èxpêrieê¡tal sessicn conpris€
Page 67 and 68: PSOCTDIJS! A. Delayed Conditj_on€
Page 69 and 70: Du.ring surgêrl, a scalp vas used
Page 71 and 72:
a1 prûcedures lierê doûe j.r¡ t
Page 73 and 74:
thê last pre-operativ€ day aåd
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considë¡aticì. .fôr a rdor€ d
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HhÊn thê sìlFerimposed .I/0 coDr
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actiyity colr:tter êtc, Ss j-! the
Page 81 and 82:
Figure 4, t{ean of the totaL nueber
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Sigurs 5. l{€an of a) total l€v
Page 85 and 86:
Íigure 6. ïhe n€an Ëespc¡s€
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3ì-gure ?. ThË d.if ferÈ¡ce pto
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figurê 8. Þ- plot of the H CD on
Page 91 and 92:
Figurè 9" the phese p].ane repr€
Page 93:
Yigure 10, The phase diagran Õf be
Page 96 and 97:
-lP coO DP/DT i.60 (t-- -c I (t o -
Page 98 and 99:
.a r O< co,
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.00 16 .00 B l. 00 T ( ÞAYJ
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î ) r(, tlJ I F = U) J I t rd o ul
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last t'¡o ti$ê blocks. These resu
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shorte¡ 1at€nciês ,the trajêct
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(n td (n z. o o_ U) td É. J t-o F
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CAUDATE OPERATED CONTROL N=5 :::[ -
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Þro; - prl d. 00 0. 20 0. q0 -t C)
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acLti+l',àn af t/o & rest svrger¡
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ç ô F
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_1 3ã coF
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a F Ë .9. ô DPlDT 0. ûrl o) -J -
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-0.12 -0.10 -0. 0B DPlDT -0. 06 -0.
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oB jo- 10/¿c
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perrfìanent-l'y êtaxicrthough t¡
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êspo¡sÈ of the slstem flas Colì
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¡igure 24. l{ealì of tatal nünb
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figure 25. The mêan of a) totâl l
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Figure 26. The ean respors€ laten
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Figure 2?. Th€. differ€ncê Fl-
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figurë 28. P Flot Õf Ð-1 syst€
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',' O< O¿I æF
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16'r.00 2t..00 url.00 I'i. 00 T ( D
Page 145 and 146:
0uaJ o/1 {î foÍaÚ'¡z-\ I .sJ ¿
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h0'0- IA/ ¿C
Page 149 and 150:
.n,vd, oJ t/o I, 1.68 P
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LAST DAY ON DCA €-o CEREBELLAR SS
Page 153 and 154:
ìu$ber of rei¡forc€d 1€ver F
Page 155 and 156:
figure 35. Beans o'f altst-al lever
Page 157 and 158:
fj-guEê 36. Thê ¡Þêa¡¡ respo
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Figurê 37. P{0}-P{T) plct cf !-r c
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Figur-- 38. P plct of ¡-I C an DC
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Fígure 39 P flot of t-.tr c group
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Figure 40 P plot of D-I c grcup ait
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Pigure 41. Phase repres€ìtation
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figure 42. Phase diagraB Ð{ t-f c
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figure .43. Phasè diagram of Ð-I
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GÊOüP V the group sÍtå bilatera
Page 175 and 176:
Pr€-operat j,qely the r€sFo¡se
Page 177 and 178:
FiguEê 49. Aciívity levêl of fro
Page 179 and 180:
figure 45. geans of total- I}r bÊr
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I'igure 46. Effects of 2.5eg/r'kg d
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Figure 4?. Þlean resporse låt€n
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Figure ¡¡8. Ðiffer+nce plot I {0
Page 187 and 188:
Figüre 49. F pl-ot of th€ frcrta
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'rigure 50" Phasè pla¡ìe reFrese
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figure 51. P plot cf frÕntâl €y
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figure 52. P plot of Érontal syst
Page 195 and 196:
figure 53. Phas€ dLagrâm .f lron
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figure 54, lesioning. focüs around
Page 199 and 200:
gigure 55. EltinctiÕn curv€s of
Page 201 and 202:
GRoUP v.r the group *ith bil-at€r
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Sj.gure 56" The neans of a) tctaL l
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Figure 5?. ¡leân r€sponse lat
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Figurê 58. titferÈnce plct of the
Page 209 and 210:
FiguEe 59. P çlot of the frontal s
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¡'igu¡e 60. F plot cf the troãta
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Figlrre 61. ? plct of the systeû s
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-!l: _l O ne tnt 0. 00
Page 218 and 219:
¿ 09'1 I P O n) I P O F tl rcl 1\
Page 221 and 222:
cRoup vIT t*e qxoup ¡{ith bilãt
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initial ¡egât:i-ve relative èrro
Page 225 and 226:
Y I LIJ II-þ ö P CD control n-3 m
Page 227 and 228:
(n L] (n ;Z o o_ (Ð Ld r J F o F [
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1 () Ld 2 No Coireclionol Input C)
Page 231 and 232:
D I 'T: I - f tlJ 5-00 P r0) 3. 00
Page 234 and 235:
Tigure 68, P f lo+- of P CD systen
Page 236 and 237:
liEurë 59. P pl-ct oÍ P CD systë
Page 238 and 239:
figutre 70. thas€ plar¡e rep.res
Page 240 and 241:
figurê ?1. thase d.iagraûr e1èct
Page 242 and 243:
gigurê ?2. phase d j.agxam of P C
Page 244 and 245:
Figure 73. trxtj.!ìction cqrÌes o
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GROI¡P VIII the group ljith shan l
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predomi.natj-ng forc: Õf erti.ncti
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U) l! U) z o o- U) ¡.rJ E. J F o F
Page 252 and 253:
t Þ c õ' J g (D
Page 254 and 255:
_ P (T] 0-20 0.40 P (0) c0. 00
Page 257 and 258:
Fågure ?8. P llût of P cX C pcior
Page 259 and 260:
fÍgure 79. P plot cf P cD c subsê
Page 261 and 262:
Íigure 80" Phase dj-agra! cf P CÐ
Page 263:
yígure 81. ?hâs€ diagran of p C
Page 267 and 268:
GAOü.P VIITI the norcal control gr
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p].ots of the N group bêfcr€ and
Page 271 and 272:
figure 84. th€ seans af al cèal
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Figure 85. T!€ úean resçcnsê l
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figure 86, The diff€Ë€nc€ pl
Page 277 and 278:
giEure 87. P p1Ðt af the ncrnaì s
Page 279 and 280:
FigurÐ 88. I plot of the Bor¡ìal
Page 281 and 282:
Figure 89. .P Flot of the rìornal
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Figure 90. Phase diagran of the nor
Page 285 and 286:
figurê 9'l . Phesê ðiagraB ci th
Page 287 and 288:
Figüre 92. Phase plaae represenr-a
Page 289 and 290:
N TS ü1,Ì S: THB IiISTOI.OGÏCÀL
Page 291 and 292:
Th€ s€ct j-cns of the corpus c
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Du€ tc the closeness of thê l*si
Page 295 and 296:
quadrant j.n th. right heaisçh€x
Page 297 and 298:
the lesianing cuErent prcdüceü a
Page 299 and 300:
figure 93. Ðiagrannìatj.c rÊpr+s
Page 301 and 302:
Ðj-agra$ Ð. À diagran ct a braiq
Page 303 and 304:
Ðiagram c.À diagran Ðf a brain s
Page 305 and 306:
Diagran 8. Ðiagraus cf brai¡ spec
Page 307 and 308:
Ðiagran À. A diagEar!ì af a bila
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'1:' t" rat # 85, sJ-ide -/ Z,area
Page 311 and 312:
at ,# 51 , slide 1J point of entry
Page 313 and 314:
_. \- I ¡ s lid.e ;f 14 slide # 15
Page 315 and 316:
Ea-. ¡at # 81, slide t' 4 rat ,.f
Page 317 and 318:
tu¡€s. Co¡ìsequently àher€
Page 319 and 320:
Ï/Ð ccntf,c1. Iio*eveE,i-h€ beh
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voluntary u¡skil-I€d movenênts
Page 323 and 324:
nê¡nely tàê ahility -tro dêIay
Page 325 and 326:
The post-oFerative testíng sèssio
Page 327 and 328:
a!. d Erocks al-l- i.np1i*d th€ e
Page 329 and 330:
REFTASNCES âtlEian, E.Ð. After€
Page 331 and 332:
Inhibitcry ¡esponses to Lasal- gan
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disordârs ct mcvement.I.cndo¡:Oxf
Page 335 and 336:
çross,C,Ð. Ccnpar j.sc¡ Ði thê
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llarren E AN€rt{€ds.},T}€ Frc
Page 339 and 340:
of T €C€At ne sì or y a n å m
Page 341 and 342:
Nautard.J.¡l . Sc ìê etfereat cc
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York: Ap FL€tcn-C€ntury cEsf ts
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Toaonicr!Ì. :¡tlo. to nonlirìear
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ÀPFTNDI T 1
Page 349 and 350:
tla lasz u se d the e.lastic spring
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index is conput€d âad fêd ¡ack
Page 353 and 354:
tendencj.es cf a freqre¡cy distrib
Page 355 and 356:
the un knar¿n €q uaiio¡s. l{he
Page 357 and 358:
statistical êstimaticr, !chich doe
Page 359 and 360:
¿n9 of the bêhavioural systens lo
Page 361 and 362:
nois€s/cont an anants. ovÊraIl.,
Page 363:
CEREEEI-LUM IVlOTOR ÜCRTEX CONTROL
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The EffĘcts of In Partial 3ėĄLfil1n€nt of Tle B€qüireûents for Eh ...

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