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Hyperbare Zuurstoftherapie: Rapid Assessment - KCE

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99 Hyperbaric Oxygenation Therapy <strong>KCE</strong> Reports 74<br />

9 APPENDICES<br />

APPENDIX FOR THE CHAPTER ON CLINICAL<br />

EFFECTIVENESS (CHAPTER 3)<br />

SEARCH STRATEGY<br />

As explained in the chapter on clinical effectiveness, most of the individual RCTs have<br />

been performed in small groups. Therefore, we have focussed our search on metaanalyses<br />

and systematic reviews. Exploratory searches learned that the MeSH term<br />

‘hyperbaric oxygenation’ covered very well the subject but we additionally also used these<br />

words as keyword in our Medline and Embase searches.<br />

All searches were performed in early December 2007 and details about the searches in<br />

Medline/Pubmed and Embase are shown in Table 38. We additionally searched the CRD<br />

databases (DARE, NHS/EED and HTA) with the MeSH term ‘Hyperbaric oxygenation’,<br />

providing 48 hits, and the several Cochrane databases with the same MeSH term leading<br />

to 271 documents. Overall 472 references were obtained through this procedure, in<br />

many cases, however, either duplicates of what was detected in the previous searches<br />

or individual clinical trials. After electronic elimination of duplicates we retained 372<br />

references. The final selection and exclusion process of manuscripts is represented in<br />

the flow chart in Figure 1 in the chapter on clinical effectiveness.<br />

Table 38. Search strategy and results for Medline/Pubmed and Embase<br />

Medline (Pubmed)<br />

#1 Search hyperbaric oxygenation[Mesh] 8459<br />

#2 Search systematic[sb] 99648<br />

#3 Search #1 AND #2 86<br />

#4 Search hyperbaric 11439<br />

#5 Search oxygenation 41576<br />

#6 Search #4 and #5 8597<br />

#7 Search #1 or #6 8597<br />

#8 Search #7 and #2 87<br />

#9<br />

Embase<br />

# 8 and Publication Date from 2000/01/01 82<br />

#1<br />

('hyperbaric oxygenation'/exp OR 'hyperbaric oxygenation')<br />

AND [2000-2007]/py<br />

3013<br />

#2<br />

('systematic review'/exp OR 'systematic review') AND<br />

[2000-2007]/py<br />

27830<br />

#3 #1 AND #2<br />

71

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