Hyperbare Zuurstoftherapie: Rapid Assessment - KCE
Hyperbare Zuurstoftherapie: Rapid Assessment - KCE
Hyperbare Zuurstoftherapie: Rapid Assessment - KCE
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
28 Hyperbaric Oxygenation Therapy <strong>KCE</strong> Reports 74<br />
No direct effect on minor amputations was found (see Figure 12), but it can be<br />
anticipated that the avoidance of major amputations results in an increase of minor<br />
amputations, indicating treatment success.<br />
One small trial (n=16) concerned venous ulcers and only suggested a significant benefit<br />
of HBOT at six weeks (reduction in ulcer size). For arterial and pressure ulcers not<br />
satisfactory trials were identified in this review. The authors, however, express cautious<br />
interpretation of these results in view of the small number of patients included in those<br />
trials. Forest plots illustrating these findings are shown in Figure 10 to Figure 13.<br />
Figure 10. Diabetic ulcers: Major amputations<br />
Source: Kranke et al. 32<br />
Figure 11. Diabetic ulcers: Major amputations subgroups by use of sham<br />
Source: Kranke et al. 32