An Analysis on Danish Micro Data - School of Economics and ...
An Analysis on Danish Micro Data - School of Economics and ...
An Analysis on Danish Micro Data - School of Economics and ...
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experience symptoms <strong>of</strong> depressi<strong>on</strong> <strong>on</strong>ce in their life. After the first depressi<strong>on</strong>, the risk <strong>of</strong> getting<br />
another depressi<strong>on</strong> raises to 50 % <strong>and</strong> after a sec<strong>on</strong>d depressi<strong>on</strong> the risk for recurrence rises to 70<br />
%. 10 The lifetime-risk is twice as high for women, as it is for men. The <strong>on</strong>set <strong>of</strong> the disease occurs<br />
typically between the age <strong>of</strong> 40 <strong>and</strong> 50. The co-morbidity is very high, since 50 % <strong>of</strong> the patients<br />
also suffer from other mental disorders. Also the mortality for depressi<strong>on</strong> is high, since it can lead<br />
to suicide. Am<strong>on</strong>g the very depressed, about 15 % commit suicide. 11 As earlier menti<strong>on</strong>ed, the risk<br />
<strong>of</strong> recurrence is high, <strong>and</strong> in the worst case it can lead to a chr<strong>on</strong>ical depressi<strong>on</strong> which lasts for<br />
several years.<br />
In general the prognosis for depressive episodes is good, but <strong>on</strong> the l<strong>on</strong>g term with recurrent<br />
episodes the prognosis is less favourable. This is due to the fact that the risk <strong>of</strong> suicide is high <strong>and</strong> a<br />
lot <strong>of</strong> patients take early retirement. 12<br />
Aetiology<br />
Both internal <strong>and</strong> external factors can cause a depressi<strong>on</strong>. Certain factors cause a depressi<strong>on</strong> for <strong>on</strong>e<br />
pers<strong>on</strong>, but not the other. This can be explained by the so-called vulnerability-stress model. 13 The<br />
development <strong>of</strong> a depressi<strong>on</strong> can be explained as a functi<strong>on</strong> <strong>of</strong> a biological foundati<strong>on</strong> for<br />
developing a depressi<strong>on</strong>, which is partly genetically determined, <strong>and</strong> <strong>of</strong> a trauma. 14 The larger the<br />
biological foundati<strong>on</strong> is the smaller trauma it takes to trigger <strong>of</strong>f a depressi<strong>on</strong>. <str<strong>on</strong>g>An</str<strong>on</strong>g>d this also works<br />
the other way around; a larger trauma just requires a small biological foundati<strong>on</strong> to trigger <strong>of</strong>f a<br />
depressi<strong>on</strong>. The psychological <strong>and</strong> biological causes <strong>of</strong> depressi<strong>on</strong> are c<strong>on</strong>nected. The vulnerabilitystress<br />
model can be seen from several angles. A pers<strong>on</strong> can be particularly vulnerable due to either<br />
psychological or biological reas<strong>on</strong>s. From a psychological viewpoint the pers<strong>on</strong> can have either a<br />
very perfecti<strong>on</strong>ist pers<strong>on</strong>ality or a very dependent pers<strong>on</strong>ality. Also biological factors play a part<br />
when a pers<strong>on</strong> is very vulnerable to depressi<strong>on</strong>. These factors have not been entirely discovered yet,<br />
but <strong>on</strong>e knows that heritability plays a part in the development <strong>of</strong> depressi<strong>on</strong>. Children have a 10-15<br />
% increased risk <strong>of</strong> developing a depressi<strong>on</strong> if either <strong>on</strong>e <strong>of</strong> their parents has had depressive<br />
episodes.<br />
The stress-comp<strong>on</strong>ent can also be seen from both a psychological <strong>and</strong> a biological angle. External<br />
events, like serious illness, accidents, divorce or death, can trigger <strong>of</strong>f a depressi<strong>on</strong>. Seen from a<br />
10 Berndt et al. (2002)<br />
11 Day Poulsen et al. (2004)<br />
12 Day Poulsen et al. (2004)<br />
13 Day Poulsen et al. (2004)<br />
14 Day Poulsen et al. (2004)<br />
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