LIFE09200604007 Tabish - Homi Bhabha National Institute
LIFE09200604007 Tabish - Homi Bhabha National Institute
LIFE09200604007 Tabish - Homi Bhabha National Institute
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Results<br />
Fig. 8: Frequency of second primary cancers in study subjects (n=24). Values in parenthesis denote<br />
the actual number out of 24 subjects in each category.<br />
All patients had both cancers in UADT except 4 patients who had one cancer<br />
in UADT and the second cancer in lung, breast or acute myeloid leukaemia. All UADT<br />
cancers were histologically squamous cell carcinomas. Various regions in buccal<br />
mucosa dominated in first primary cancer (42%) as well as site of second primary<br />
cancer (50%). Tongue (21%) and larynx (21%) were also frequent sites of first primary<br />
cancer while cancer of hard palate (13%) and tongue (9%) were next most frequent<br />
cancers as second primaries (Fig. 7, Fig. 8). Detailed demographics of MPN patients<br />
accrued for the study is described in Table 5.<br />
Blood sample from healthy controls that were cancer free, and were habit and<br />
age matched, were collected mainly from Advanced Centre for Treatment Research and<br />
Education in Cancer (ACTREC), while two samples were taken from healthy subjects<br />
belonging to Shendurjane Village, Wai, Satra, India. While collecting sample subjects<br />
were analysed with respect to gender, age, location, habit and family history of cancer,<br />
based on questionnaire similar to cases. Detailed demographic of control samples is<br />
described in Table 6.<br />
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