Unani Formulation - Jamia Hamdard

time.
Sue Mizaj (Imbalance of temperament): Reason for preparation compound
drug concerns the extent of the imbalance of the humour; that is, if
there is no single drug with enough force to restore balance, it is compounded
with others that are stronger (or weaker) in the component desired.
Thus, the tendency of the humour to continue in the direction of
further imbalance is opposed.
Site of action: The affected parts of body may be far from the site of
administration, and drugs are mixed into the compound that speeds
the drug to the site of action.
Synergistic action: The strength and acuteness of the illness may be
such that no single drug is sufficient against it. The drugs are mixed
so that the ingredients have a synergistic action and effect.
Disease strength: The strength and importance of the diseased organ
must be taken together. Usually a drug to dissolve a tumor is
compounded with one to ease the symptoms.
There is always a difference between drugs, their doses and usage.
Sometimes the effects of both may be desired.
Calculation of Amount of Compound Drugs
Calculation of the Mizaj of compound formulation
Ancient Hakim established the temperament of drugs on their own
experiences and observations. They also formulated some principles. In
later period Hakim established the temperament of single drugs in the
light of some ancient principles and it was established that action of drug
is due to its temperament. For example if a drug produces heat in body, it
will be stimulant. If a drug produces coldness in body, it will be depressant.
It was basically divided in two types: Haar (Hot) and Barid (Cold).
Further these were divided in four categories according to their action,
ingredients and period of action. Besides these there were Yaboosat (Dryness)
and Ratoobat (Moisture). In preparation of Morakkabat (Compound
formulation), it is considered that that there should be a particular
balance in the constituents of Morakkabat (Compound formulation). Later
the principles to establish the Mizaj of Morakkabat were formulated.
These are described as under.
1. Some Morakkabat (Compound formulation) contain Hot and
Dry drugs. For example following compound contains 3 hot drugs
and 3 cold drugs shown in Table No. 1
In the calculation of the weights of each drug to be included in a
compound, following factors to be considered:
Distance of the affected organ from the stomach if drug is given
orally.
Ill-effects on other organs
Its benefits
Its usefulness, alone or with other drugs
Strength of the nature of the drugs
The effect of the drugs
Drugs in the formulation weaken its effect?
Hot Cold
Drugs A B C Total A B C Total
Temperament 1 2 1 4 1 2 1 4
In above mentioned table Mizaj of both hot and cold constituent is
equal as 4 so Mizaj of this Morakkab will be Motadil (Normal)
2. If a Morakkab (Compound formulation) contains either only
hot or only cold drugs following method should be adopted.
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