WORKSHOP BOOK Fluorescent in Situ Hybridisation - FISH - on Human Sperm
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
<strong>Sperm</strong> morphology<br />
Data regard<str<strong>on</strong>g>in</str<strong>on</strong>g>g associati<strong>on</strong> of sperm aneuploidy rate and<br />
sperm morphology not yet c<strong>on</strong>sistent<br />
Severe sperm morphology abnormalities (macrocephallicmulti-flagellated<br />
sperm syndrome) display high levels of<br />
disomy and polyploidy compared to c<strong>on</strong>trols<br />
Perr<str<strong>on</strong>g>in</str<strong>on</strong>g> et al, 2008; Brahem et al, 2011<br />
Patients with globozoospermia have a moderate to more<br />
pr<strong>on</strong>ounced <str<strong>on</strong>g>in</str<strong>on</strong>g>crease of disomy<br />
Morel et al, 2004; Brahem et al, 2011<br />
Hands-<strong>on</strong> Workshops, Thessal<strong>on</strong>iki, 30.08 – 05.09 2014<br />
25<br />
C<strong>on</strong>clusi<strong>on</strong>:<br />
Semen parameters<br />
There is a str<strong>on</strong>g and <str<strong>on</strong>g>in</str<strong>on</strong>g>verse correlati<strong>on</strong> between<br />
aneuploidy risk and sperm count<br />
The relati<strong>on</strong>ship between an <str<strong>on</strong>g>in</str<strong>on</strong>g>creased rate of<br />
chromosome abnormalities <str<strong>on</strong>g>in</str<strong>on</strong>g> spermatozoa and<br />
asthenozoospermia or teratozoospermia cannot be<br />
clearly established<br />
Hands-<strong>on</strong> Workshops, Thessal<strong>on</strong>iki, 30.08 – 05.09 2014<br />
26
Change language