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08-09 Graduate Catalog/w pics - University of Louisiana at Monroe

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GRADUATE COURSES 147<br />

the physiochemical properties and metabolism <strong>of</strong> genetically engineered biopharmaceuticals.<br />

Prerequisites: 4<strong>08</strong>, 4<strong>09</strong>, and credit or registr<strong>at</strong>ion in 414, or with Consent <strong>of</strong> Department Head.<br />

423. MEDICAL IMMUNOLOGY. 2 cr. Cellular and serum immunology. Antibody structure and<br />

function. Types <strong>of</strong> antigen antibody reactions. Immunosuppression, tolerance and<br />

enhancement. Systems medi<strong>at</strong>ing immunologic injury and inflamm<strong>at</strong>ion.<br />

Immunogenetics. Prerequisites: 4<strong>08</strong>, 412, 436.<br />

432. PHARMACEUTICS III. 3 cr. The interrel<strong>at</strong>ionship between formul<strong>at</strong>ion factors and<br />

pharmacokinetic aspects <strong>of</strong> drug absorption, distribution, metabolism, and excretion.<br />

Prerequisite: 403.<br />

454. LAW. 3 cr. Local, st<strong>at</strong>e and federal laws, rules and regul<strong>at</strong>ions rel<strong>at</strong>ing to the practice <strong>of</strong><br />

Pharmacy. Prerequisite: Second Year Pharmacy.<br />

479. NUCLEAR PHARMACY. 2 cr. Handling and storage <strong>of</strong> radioisotopes and their applic<strong>at</strong>ion to<br />

pharmacy. The <strong>of</strong>ficial radiopharmaceuticals and non-<strong>of</strong>ficial radiopharmaceuticals <strong>of</strong> merit<br />

employed in therapy will be considered. Prerequisite: Second year pharmacy.<br />

For <strong>Gradu<strong>at</strong>e</strong>s Only<br />

500. MOLECULAR STRUCTURE AND FUNCTION OF PROTEINS. 3 cr. This course is designed to<br />

introduce gradu<strong>at</strong>e students to basic concepts and techniques in the study <strong>of</strong> protein structure<br />

and function. Course coverage will include structural determinants, rel<strong>at</strong>ionship <strong>of</strong> structure to<br />

function, thermodynamics <strong>of</strong> protein interactions, protein/ligand interactions, kinetics, transition<br />

st<strong>at</strong>e theory, enzyme mechanisms and protein purific<strong>at</strong>ion techniques.<br />

502. PRODUCT DEVELOPMENT. 4 cr. Theoretical and practical aspects involved in the formul<strong>at</strong>ion<br />

<strong>of</strong> a pharmaceutical; emphasis on research techniques employed in developing an acceptable<br />

medicinal product. Two hours lecture and six hours labor<strong>at</strong>ory. Prerequisites: 432.<br />

513. PHARMACOKINETICS. 3 cr. A quantit<strong>at</strong>ive tre<strong>at</strong>ment <strong>of</strong> the dynamics <strong>of</strong> drug absorption,<br />

distribution, metabolism, and excretion, including the development <strong>of</strong> m<strong>at</strong>hem<strong>at</strong>ical models for<br />

these processes. Applic<strong>at</strong>ion <strong>of</strong> analog and digital comput<strong>at</strong>ion will be discussed. Prerequisites:<br />

M<strong>at</strong>hem<strong>at</strong>ics 301 or 401, and/or Consent <strong>of</strong> Department Head.<br />

514. ADVANCED BIOPHARMACEUTICS. 3 cr. An advanced tre<strong>at</strong>ment <strong>of</strong> factors affecting drug<br />

availability from dosage forms and the influence <strong>of</strong> the route <strong>of</strong> administr<strong>at</strong>ion and the dosage<br />

regimen on drug availability. Prerequisite: 513 or Consent <strong>of</strong> Department Head.<br />

515. CLINICAL PHARMACOKINETICS. 3 cr. The applic<strong>at</strong>ion <strong>of</strong> pharmacokinetic principles to the<br />

safe and therapeutic management <strong>of</strong> the individual p<strong>at</strong>ient. Prerequisites: 432, 439 and/or<br />

Consent <strong>of</strong> Department Head.<br />

521. ADVANCED PHARMACOLOGY. 3 cr. Cellular and molecular mechanisms <strong>of</strong> drug action.<br />

Prerequisites: 413, 414 or consent <strong>of</strong> Department Head.<br />

522. ADVANCED PHARMACOLOGY LABORATORY. 3 cr. Labor<strong>at</strong>ory techniques used to evalu<strong>at</strong>e<br />

drug action. Nine hours labor<strong>at</strong>ory. Prerequisite: Credit or registr<strong>at</strong>ion in 521.<br />

523. FORENSIC TOXICOLOGY. 2 cr. Quantit<strong>at</strong>ive and qualit<strong>at</strong>ive toxicological analyses. Six hours<br />

labor<strong>at</strong>ory. Prerequisite: 489.<br />

525. INDUSTRIAL TOXICOLOGY. 2 cr. Chemical hazards in the workplace; regul<strong>at</strong>ory and medicolegal<br />

programs, product safety, worker health protection, chemical-rel<strong>at</strong>ed health risk<br />

assessment. Prerequisite: 489.<br />

527. NEUROPHARMACOLOGY. 4 cr. Advanced discussion <strong>of</strong> the liter<strong>at</strong>ure and methodology<br />

rel<strong>at</strong>ed to the action <strong>of</strong> drugs in neurological systems. Prerequisites: 413, 414, or Consent <strong>of</strong><br />

Department Head.<br />

529. IMMUNOPHARMACOLOGY. 2 cr. A study <strong>of</strong> the interactions between pharmacologic agents;<br />

the immune systems and their biological function. Prerequisites: 414, 423.<br />

531. SYNTHETIC MEDICINALS. 3 cr. A study <strong>of</strong> the methodologies and str<strong>at</strong>egies used in the<br />

synthesis <strong>of</strong> compounds <strong>of</strong> pharmacological significance. Prerequisites: Chemistry 531, 532 or<br />

Consent <strong>of</strong> Department Head.<br />

532. CHEMISTRY OF HETEROCYCLIC COMPOUNDS. 3 cr. Chemical and physical properties,<br />

nomencl<strong>at</strong>ure, and synthesis <strong>of</strong> heterocycles commonly found in compounds <strong>of</strong> biological and<br />

pharmacological importance. Prerequisites: Chemistry 531, 532, or Consent <strong>of</strong> Department Head.<br />

534-535. NATURAL PRODUCTS. 3 cr. each. Study <strong>of</strong> n<strong>at</strong>ural products used in medicine, pharmacy<br />

and allied fields. Emphasis is placed on isol<strong>at</strong>ion, purific<strong>at</strong>ion and synthetic deriv<strong>at</strong>ives. One<br />

hour lecture and six hours labor<strong>at</strong>ory. Prerequisite: Consent <strong>of</strong> Department Head.<br />

540. BIOSTATISTICS. 3 cr. The theoretical and applied techniques <strong>of</strong> d<strong>at</strong>a collection, analysis, and<br />

interpret<strong>at</strong>ion in pharmaceutical research. Prerequisite: Psychology 439.

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