Brucellosis 2003 proceedings - PHIDIAS

Short Oral Communications
Vaccines
group. Five out of five gerbils survived in the groups where all three antigens were
combined and in the groups where GRA7 was combined with SRS2 and with MIC3.
Brain, spleen, lung and liver tissues were fixed in formal saline and subjected to
histopathological analysis. Tissues that had the largest number of lesions per field of
examination were awarded the highest scores. The lowest score was found in the
GRA7, MIC3 combination group followed by the SRS2, MIC3 group. These
preliminary results indicate that this approach may be a practical method for
prophylaxis against N. caninum.
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