What's new AAPOS 2008 - The Private Eye Clinic

clusterin mRNA. Clusterin showed possible important functioning in tumor suppression
by the VHL gene product and the potential to be a novel biomarker in retinal
hemangioblastoma associated with VHL.
Cionni endocapsular ring implantation in Marfan’s syndrome
Bahar I, Kaiserman I, Rootman D.
Br J Ophthalmol 2007 Nov; 91:1477-1480.
This is a case series of 15 eyes of 12 patients (aged 19-56) with Marfan syndrome and
subluxated lenses. A 2-eyelet Cionni ring and an AcrySOf foldable IOL were implanted
in 13 eyes. Two eyes had trans-scleral IOL fixation in the ciliary sulcus. In all eyes,
capsular bag centration was excellent. In this study the Cionni ring enable the capsular
bag centration. However, the authors noted some intraoperative limitations. 1) With an
unstable lens, a central capsulorhexis was at times difficult, and often small. 2) In cases
with extensive subluxation, implantation could be difficult. 3)They noticed the capsular
bag of the Marfan patient was sometimes smaller than that of normal eyes so that the
standard Cionni ring may be too large for the kind of bag, and implanting it increases
the risk of a rip or tear of the bag. Preoperative vision ranged from 20/50 to CF and
improved to better than 20/40 in all eyes. They note that this procedure requires a
highly skilled surgeon and cannot always be completed.
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RETINOBLASTOMA
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