What's new AAPOS 2008 - The Private Eye Clinic
What's new AAPOS 2008 - The Private Eye Clinic
What's new AAPOS 2008 - The Private Eye Clinic
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PLASTICS<br />
Conjunctival epithelial changes induced by cilia in patients with epiblepharon or<br />
entropion.<br />
Kim C, Shin YJ, Kim NJ, Khwarg SI, Hwang JM, Wee WR.<br />
Am J Ophthalmol. 2007 Oct;144(4):564-9. Epub 2007 Aug 9.<br />
PURPOSE: To evaluate the effect of mechanical trauma induced by cilia on the<br />
conjunctival epithelium in patients with epiblepharon or entropion and to evaluate<br />
changes in epithelium after surgical correction in patients with entropion. DESIGN:<br />
Case-control study.<br />
METHODS: One hundred and seven eyes of 61 patients were enrolled in this study and<br />
were divided into three groups: the epiblepharon group (n = 59), the entropion group (n<br />
= 17), and the age-matched control group for the epiblepharon group (n = 31).<br />
Impression cytologic specimens were obtained from nasal and temporal bulbar<br />
conjunctiva of the epiblepharon and control groups immediately after the induction of<br />
general anesthesia. In the entropion group, these were obtained before and one month<br />
after surgical correction. Conjunctival changes were graded using the Tseng method<br />
and goblet cell densities were compared.<br />
RESULTS: Cytologic scores were significantly higher in the epiblepharon group than in<br />
the control group (P < .001), and goblet cell densities of nasal and temporal conjunctiva<br />
were significantly lower in the epiblepharon group than in the control group (P = .044<br />
and P = .018, respectively). In the entropion group, postoperative scores were<br />
significantly lower than preoperative scores in both conjunctival areas (P = .033 and P =<br />
.003, respectively). No statistically significant difference was found between nasal and<br />
temporal conjunctiva in the three groups.<br />
CONCLUSIONS: <strong>The</strong> persistent mechanical trauma by cilia in patients with<br />
epiblepharon or entropion can induce squamous metaplasia of the conjunctival<br />
epithelium. However, these conjunctival changes can be reversed by surgical<br />
correction.<br />
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