What's new AAPOS 2008 - The Private Eye Clinic

acid were associated with reduced risk of islet autoimmunity in children at increased
genetic risk for type 1 diabetes.
Prevalence and patterns of morphological abnormalities in patients with
childhood cancer.
Merks J, Ozgen H, Koster J, Zwinderman A et al.
JAMA 2008 Jan; 299(1):61-69.
In this fascinating study conducted in the Netherlands, the investigators examined 1,073
patients who are either long-term survivors of childhood cancer or patients with newly
diagnosed cancer. A complete physical examination was performed looking for
morphologic abnormalities. The control group of 1,007 school children of the same age
served as match controls and received the exact same type of physical examination.
They found that there were significantly more morphologic abnormalities in the patients
with cancer than patients within the control group. Blepherofimosis was found to be
associated with co-occurring morphologic abnormalities suggestive of new tumor
predisposition syndromes. The authors conclude that there are most likely
unrecognized tumor predispositions syndromes, waiting to be described by astute
clinicians.
Optical Coherence Tomography Applications in Pediatric Ophthalmology.
Salchow, DJ and Hutcheson, KA.
JPOS 2007;44:335-349.
Invasive and contact diagnostic testing methods are difficult to utilize in children.
Optical coherence tomography (OCT) has become a widely-used non-contact method
to obtain cross-sections of various ocular structures. Normative values for children
have been published and should be used when measuring macular and RNFL
thickness, or when assessing the optic disc using OCT.
Children older than 3 years can usually cooperate for OCT imaging. This review article
describes the principles and clinical applications of OCT with special attention to
pediatric ophthalmology.
Assessment of Psychomotor Development Before and After Strabismus Surgery
for Congenital Esotropia.
Tukkers-van Aalst, FS et al.
JPOS 2007;44:350-355.
Infantile esotropia occurs in up to 30% of children with neurologic
and developmental problems, but is rare among the strabismus population with an
estimated prevalence of 0.27%. The appropriate age at which to perform surgery is
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