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What's new AAPOS 2008 - The Private Eye Clinic

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GLAUCOMA<br />

Surgical outcome of primary developmental glaucoma: a single surgeon's longterm<br />

experience from a tertiary eye care centre in India.<br />

Mandal AK, Gothwal VK, Nutheti R.<br />

<strong>Eye</strong>. 2007 Jun;21(6):764-74<br />

Six hundred and twenty-four eyes of 360 consecutive patients who underwent primary<br />

combined trabeculotomy-trabeculectomy (CTT) for PDG from January 1990 to June<br />

2004 were studied. <strong>The</strong> main outcome measures were pre- and postoperative<br />

intraocular pressures (IOPs), corneal clarity, visual acuities, refractive errors, success<br />

rate, time of surgical failure, complications, and factors associated with poor outcome.<br />

IOP reduced from 28.1+/-7.5 to 14.9+/-5.9 mmHg (P35 mmHg and two-fold in cases with a history of prior glaucoma<br />

surgery. <strong>The</strong>re were no major intraoperative complications, bleb-related infection, or<br />

endophthalmitis.<br />

<strong>The</strong> effects of sevoflurane and ketamine on intraocular pressure in children<br />

during examination under anesthesia.<br />

Blumberg D, Congdon N, Jampel H, Gilbert D, Elliott R, Rivers R, Munoz B, Quigley H.<br />

Am J Ophthalmol. 2007 Mar;143(3):494-9. Epub 2007 Jan 2.<br />

PURPOSE: We studied the effects on intraocular pressure (IOP) of anesthesia<br />

administered during examination under anesthesia (EUA) in children.<br />

METHODS: This randomized trial compared IOP after inhaled sevoflurane gas to that<br />

after intramuscular ketamine hydrochloride in children undergoing EUA. IOP was<br />

measured in 30 eyes with TonoPen XL (Mentor, Inc, Norwell, Massachusetts, USA) as<br />

soon as possible after anesthesia induction (T1) and two, four, six, and eight minutes<br />

thereafter. At the same times, we recorded systolic and diastolic blood pressure (SBP,<br />

DBP) and heart rate (HR).<br />

RESULTS: Compared with the mean IOP at T1, IOP in the sevoflurane group was<br />

significantly lower for all measurements from two to eight minutes thereafter (mean<br />

decrease in IOP: two minutes = 12%, four minutes = 19%; six minutes = 19%; eight<br />

minutes = 17%, all P < or = .01). In the ketamine group, mean IOP was not significantly<br />

changed from T1 through six minutes, whereas at eight minutes, it was 7% lower (P =<br />

92

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