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Master's Thesis - Studierstube Augmented Reality Project - Graz ...

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3.3 Signal localization<br />

would result in an ideal square slice profile. In practice the frequency range is higher<br />

since on the one hand a perfect sinc pulse is technically not possible and on the other<br />

hand a sharper desired slice profile requires a higher energy of the RF-pulse. Applying<br />

too much energy to a human body per time unit would lead to a warming of the<br />

tissue by more than 1 ◦ C, which can be harmful for living cells. This absorbed energy<br />

amount is called Specific Absorption Rate (SAR) and restricts the slope and the speed<br />

of switching gradients, the energy of the RF-pulses and the sharpness of the slice profile.<br />

The fact that the profiles are not ideal square cause a slice distance of more than<br />

zero or a doubled measurement time with interleaved slice measurement. Elsewhere<br />

partial volume effects would garble the resulting images depending on the sequence.<br />

Figure 3.7 shows the selection of a segment, placed perpendicular in the xy-plane<br />

by a linear gradient G z in z-direction. However, slice-selection in arbitrary direction<br />

and location needs a combination of gradients in three directions<br />

⎧<br />

⎨ G x = G ss sinθ cos φ<br />

G ss = (G x , G y , G z ) = G y = G ss sinθ sin φ<br />

⎩<br />

G z = G ss cosθ<br />

(3.24)<br />

and a RF-pulse<br />

ω hf = ω 0 + γG ss c 0 , ∆ω = γG ss ∆c (3.25)<br />

with the excitation frequency ω hf , bandwidth ∆ω, the center of the segment c 0 and its<br />

thickness ∆c.<br />

A frequency response of all spins situated in the selected segment will be detectable<br />

after an excitation done as described in this section. Obviously further dispartment of<br />

the signal will be necessary to locate a certain volume element’s response within the<br />

activated segment.<br />

3.3.2 Voxel Selection<br />

During the precession period the second step of spatial localization is called frequencyand<br />

phase encoding. Frequency encoding makes the oscillating frequency of the complex<br />

MR-signal dependent on its spatial origin which can be utilized to locate a column of<br />

the activated slice. How to impose different Larmor frequencies on different locations<br />

has already been described in the previous sections. We need to apply another gradient<br />

46

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