Sundhedsvidenskabelig Forskning ved Aarhus - Institutleder til ...

Hjerte-lunge-karkirurgisk afd. T, ÅRHUS UNIVERSITETSHOSPITAL, SKEJBY
Post. doc.
cand.scient.med. Samuel Koch, ph.d.
lektor, cand.scient.med. Steffen Ringgaard, ph.d.
cand.scient. Donna B. Briggs
Vigtigste satsningsområder inden for afdelingens
forskning
• Turbulence, cavitation and HITS in relation to
mechanical heart valve prostheses.
• Characterization of sound pressure level and
frequency distribution of opening and closing
sounds from prosthetic heart valves in animal
models and in patients.
• Long-term animal experimental evaluation of
prosthetic heart valves.
• Cavitation bubbles at heart valve prostheses.
• Dynamic 3D-imaging of the heart.
• Preconditioning of the porcine heart.
• Longterm porcine model for heart failure.
• Patient self-management of oral anticoagulant
therapy.
• Biomechanical evaluation of the mitral valve.
• Arrhythmias.
• Apical and percutaneous stent valves versus
open heart surgery with valve implantation.
• Off pump versus on pump surgery.
• Minimally invasive surgery.
• Bypass surgery versus PCI.
• Mitral valve surgery techniques.
• Postoperative pain modulation.
• Coagulation at heart surgery.
• Risk factor stratification models and identification.
• Renal preconditioning.
• Register based phychiatric problems, pregnancy
related issues such as fertility, abortion, birth
and risk of congenital heart defects in off spring
and questionnaire based investigations of quality
of life.
• Transcapillary exchange.
• Microcirculation and peripheral ischemia.
• Regulation of the peripheral circulation.
• Vascular prostheses, incl. infection.
• Vascular registries.
• Pharmacological therapy.
• Blood flow in arteries (magnetic resonance &
ultrasound techniques).
• Atherosclerosis.
• Carotid plaques (stroke).
• Monitoring of peripheral oedema in heart failure
patients.
• Development of a pressure sensitive sheet for
prevention of bedsore.
• Wireless transmission and remote monitoring of
heart rate variability (HRV).
• Development of nano particle based material for
construction of prosthetic heart valves.
• Studies of sternal healing after sternotomi.
• Assessment of Atrial Natriuretic Peptide (ANP)
and B-type Natriuretic Peptide (BNP) in ischemic
pig hearts after infusion of BNP and the chimerical
peptide CD-NP.
• Biomechanical investigations of air sealant procedures
in porcine lungs.
• Biomechanical studies related to chest wall
anomalies.
• Influence on the heart of sympatectomy.
• Survival in lung cancer related to DNA-profile.
• Cardiopulmonal funktion under hvile og anstrengelse
ved medfødte hjertesygdomme – specielt
univentrikulære tilstande
• Lymfefysiologi med specielt henblik på hjerteinsufficiens
og det univentrikulære kredsløb
• Sympatikus betydning for hjertefrekvens variabilitet
• Brystkassens anatomiske udformning og dens
betydning for cardiopulmonal funktion
Ph.d.-afhandlinger
Jensen, H 2009, A Novel Integrated Surgical Approach to
Chronic Functional Ischemic Mitral Valve Regurgitation:
Impact of Adding Papillary Muscle Relocation
to Down-Sized Ring Annuloplasty, Ph.d.-afhandling,
Fællestrykkeriet for Sundhedsvidenskab og Humaniora,
Aarhus Universitet.
Larsen, SH 2009, Outcome assessment following congenital
heart surgery: Mortality, morbidity, and functional
health, Ph.d.-afhandling, Aarhus Universitet.
Ng, HS 2009, Identification of Microembolic Signals Detected
by Ultrasonography, Ph.d.-afhandling, Fællestrykkeriet
for Sundhedsvidenskab og Humaniora,
Aarhus Universitet
Publikationer
Forskning
Artikel, peer-reviewed
Anderson, RH, Smerup, MH, Sanchez-Quintana, D,
Loukas, M & Lunkenheimer, PP 2009, ‘The threedimensional
arrangement of the myocytes in the
228 Sundhedsvidenskabelig Forskning ved Aarhus Universitet og Århus Universitetshospital 2009