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9th Annual International Meeting For Autism Research ... - Confex

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Program<br />

Scientific Panels<br />

123 Developmental Trajectories of Children with<br />

<strong>Autism</strong> Spectrum Disorder<br />

3:45 PM - 4:45 PM - Grand Ballroom AB Level 5<br />

Organizer: S. Georgiades; McMaster University<br />

Many longitudinal studies in ASD have documented<br />

considerable variation in outcome, ranging from<br />

remarkable improvement in some children to a decline<br />

in others. However, these results are limited by<br />

issues such as employment of convenience sampling<br />

frames, data collection from few time points, and use<br />

of small sample sizes. More recent data suggest a<br />

new way of thinking about the developmental course<br />

of ASD, in which children are described using distinct<br />

homogeneous trajectories, rather than a single<br />

heterogeneous group. This panel presents findings<br />

from two new longitudinal studies that benefit from<br />

large sample sizes, ascertainment of inception cohorts,<br />

data acquisition at multiple time-points, use of several<br />

outcomes including social-communication symptoms<br />

and functioning and problem behaviors, and novel<br />

statistical techniques. The findings emphasize that<br />

children with ASD follow distinct trajectories both over<br />

the short and long term and that this heterogeneity in<br />

developmental course needs to be taken into account in<br />

treatment planning.<br />

3:45 123.001<br />

Developmental Course of Social Communication Symptoms<br />

and Functioning in Young Children with ASD. P. Szatmari* 1 , T. A.<br />

Bennett 2 , S. Georgiades 1 , E. Duku 1 , S. E. Bryson 3 , E. Fombonne 4 ,<br />

P. Mirenda 5 , W. Roberts 6 , I. M. Smith 7 , T. Vaillancourt 8 , J. Volden 9 ,<br />

C. Waddell 10 , L. Zwaigenbaum 9 and A. P. Thompson 1 , (1)McMaster<br />

University, (2)Offord Centre for Child Studies, McMaster University,<br />

(3)Dalhousie University/IWK Health Centre, (4)McGill University,<br />

(5)University of British Columbia, (6)University of Toronto,<br />

(7)Dalhousie University & IWK Health Centre, (8)University of<br />

Ottawa, (9)University of Alberta, (10)Simon Fraser University<br />

4:00 123.002<br />

Developmental Trajectories of Internalizing and Externalizing<br />

Behaviours in Young Children with ASD. T. Vaillancourt* 1 , P.<br />

Szatmari 2 , S. Georgiades 2 , E. Duku 2 , S. E. Bryson 3 , E. Fombonne 4 ,<br />

P. Mirenda 5 , W. Roberts 6 , I. M. Smith 7 , J. Volden 8 , C. Waddell 9 , L.<br />

Zwaigenbaum 8 and A. P. Thompson 2 , (1)University of Ottawa,<br />

(2)McMaster University, (3)Dalhousie University/IWK Health Centre,<br />

(4)McGill University, (5)University of British Columbia, (6)University<br />

of Toronto, (7)Dalhousie University & IWK Health Centre,<br />

(8)University of Alberta, (9)Simon Fraser University<br />

4:15 123.003<br />

Longitudinal Change in Social Affect and Restricted and Repetitive<br />

Behavior Severity Using the ADOS. V. Hus* 1 , K. Gotham 1 , A. Pickles 2<br />

and C. Lord 3 , (1)University of Michigan <strong>Autism</strong> & Communication<br />

Disorders Center, (2)University of Manchester, (3)University of<br />

Michigan<br />

4:30 123.004<br />

Growth Trajectories of Problem Behaviors Utilizing the Aberrant<br />

Behavior Checklist. M. Maye* 1 , D. K. Anderson 1 and C. Lord 2 ,<br />

(1)University of Michigan <strong>Autism</strong> & Communication Disorders<br />

Center, (2)University of Michigan<br />

Scientific Panels<br />

124 Earlier Is Better and More Difficult:<br />

Opportunities and Challenges in Screening<br />

Children for An <strong>Autism</strong> Spectrum Disorder (ASD)<br />

in the General Population During the Second<br />

Year of Life<br />

3:45 PM - 4:45 PM - Grand Ballroom F Level 5<br />

Moderator: C. E. Rice; National Center on Birth Defects and<br />

Developmental Disabilities<br />

Organizer: C. E. Rice; National Center on Birth Defects and<br />

Developmental Disabilities<br />

Recently, there have been advances in understanding the<br />

early signs of ASDs with increased public health focus on<br />

early developmental screening. The American Academy of<br />

Pediatrics now recommends that all children be screened<br />

for developmental disabilities throughout the first few<br />

years of life and for ASDs at 18 and 24 months. Despite<br />

wide consensus that “earlier is better,” knowledge gaps<br />

exist in what “early” means and how this is successfully<br />

implemented in general population settings. Although<br />

several screening instruments have been developed for<br />

use in the 2nd year of life, data on their utility in general<br />

population settings are limited. Unlike families in clinicallyreferred<br />

or sibling research projects who may have<br />

heightened concern, families in the general population<br />

may be confronted with positive screening results before<br />

they have raised concern themselves. This panel presents<br />

the latest data on early ASD screening tools used in<br />

general population settings and explores opportunities<br />

and challenges in the during the 2nd year of life.<br />

3:45 124.001<br />

Identifying Young Children with <strong>Autism</strong> Spectrum Disorder through<br />

General Population Screening. A. M. Wetherby*, Florida State<br />

University<br />

4:05 124.002<br />

M-CHAT Best7: A New Scoring Algorithm Improves Positive<br />

Predictive Power of the M-CHAT. D. L. Robins* 1 , J. Pandey 2 , C.<br />

Chlebowski 3 , K. Carr 3 , J. L. Zaj 4 , M. Arroyo 1 , M. L. Barton 3 , J. Green 3<br />

and D. A. Fein 3 , (1)Georgia State University, (2)Children’s Hospital of<br />

Philadelphia, (3)University of Connecticut, (4)Radford University<br />

4:25 124.003<br />

Population Screening for ASD: a Comparison of M-CHAT and ESAT.<br />

J. Buitelaar*, Karakter Child and Adolescent Psychiatry University<br />

Center<br />

FrIday –PM<br />

<strong>9th</strong> <strong>Annual</strong> <strong>International</strong> <strong>Meeting</strong> <strong>For</strong> <strong>Autism</strong> <strong>Research</strong> (IMFAR) 2010 45

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