9th Annual International Meeting For Autism Research ... - Confex

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Program Scientific Panels 125 Autism Instructional Methods Study: Opportunities & Challenges for Moving Intervention into Community Settings 4:45 PM - 5:45 PM - Grand Ballroom F Level 5 Organizer: D. S. Mandell; University of Pennsylvania School of Medicine In the past few decades, >20 randomized controlled trials have shown the efficacy of behavioral interventions for young children with autism. While findings are promising, little attention has been given as to how interventions might be moved successfully to community settings so that they are effective and sustain. Efforts to transport interventions are hampered by lack of knowledge of real-world context, including teachers’ training and resources, their ability and willingness to implement complex programs with fidelity, the school climate for embracing new interventions, and the heterogeneity of the children they serve. The Autism Instructional Methods Study (AIMS) is a four-year, large-scale randomized field trial designed to examine factors associated with the effective implementation and student outcomes of two evidencebased interventions – Strategies for Teaching based on Autism Research (STAR) and Structured Teaching – for students in kindergarten-through-second-grade autism support classrooms in an urban setting. This panel presents early results of the trial, including: the ability and willingness of education staff to implement these programs with fidelity (Stahmer), first-year student outcomes and moderators of outcome (Shin), the role of classroom climate in program fidelity (Dingfelder), and lessons learned in conducting research in partnership with a large school district (Mandell). 3:45 125.001 The Autism Instructional Methods Study: What We Planned and Why We Were Wrong. D. S. Mandell* 1 , S. Shin 2 , A. Stahmer 3 and S. C. Marcus 4 , (1)University of Pennsylvania School of Medicine, (2)University of Pennsylvania, (3)Rady Children’s Hospital, (4)University of Pennsylvania School of Social Policy and Practice 4:00 125.002 Fidelity of Implementation of Evidence-Based Practice in Community Classrooms. A. Stahmer* 1 , S. Reed 1 , S. Shin 2 and D. S. Mandell 3 , (1)Rady Children’s Hospital, (2)University of Pennsylvania, (3)University of Pennsylvania School of Medicine 4:15 125.003 Student, Teacher and Classroom-Level Mediators of Outcomes for Children with Autism Spectrum Disorders. S. Shin* 1 , A. Stahmer 2 , S. C. Marcus 3 and D. S. Mandell 4 , (1)University of Pennsylvania, (2)Rady Children’s Hospital, (3)University of Pennsylvania School of Social Policy and Practice, (4)University of Pennsylvania School of Medicine 4:30 125.004 The Relationship Between Classroom Climate and Intervention Fidelity. H. E. Dingfelder* 1 , S. Shin 1 and D. S. Mandell 2 , (1)University of Pennsylvania, (2)University of Pennsylvania School of Medicine Special Presidential Lecture: Autism and Society 6:00-7:30P Grand Ballroom AB/F Speaker: Jacqueline Russell, Artistic Director, Chicago Children’s Theatre In this presentation, Jacqueline Russell shares how she and Chicago Children’s Theatre have succeeded in creating a new type of theatre for children with Autism Spectrum Disorder (ASD). This bold and unique theatre initiative began three years ago and is known as The Red Kite Project. At the heart of The Red Kite Project is interactive, multi-sensory theatre specifically tailored to meet the special needs of children with ASD and their families. For more than a decade, Jacqui Russell has used theatre games in the classroom to enhance communication and interpersonal skills in children with autism. As co-founder of Chicago Children’s Theatre, Russell’s longstanding commitment to special education turned that passion and experience into live theatre specifically for children on the spectrum. Russell has spent years studying, developing, and rehearsing this immersive form of theatre by teaming up with colleagues from the UK, educators, actors, designers, therapists and doctors, and most importantly, with the children who inspired her personal and professional journey---the students in the autism classes at Agassiz Elementary School in Chicago. The result has been the first of its kind production in the United States for these children, their families and caregivers who at last can come together to experience the elusive joys of live theatre. Poster Sessions 130 Animal Models 1:00 PM - 5:30 PM - Franklin Hall B Level 4 1:00 142 130.121 Effect of Maternal Omega-6 Rich Diets and Prenatal Stress On Autistic-Like Sociability Defi cits in Mice. K. L. Jones*, M. J. Will, P. M. Hecht, C. L. Parker, K. M. Morman and D. Q. Beversdorf, University of Missouri 2:00 143 130.122 Functional Dissection of the Autism Susceptibility Gene Slc25a12 in Model Systems. T. Sakurai* 1 , N. Ramoz 2 , M. Gazdoiu 1 , N. Takahashi 1 , N. P. Dorr 1 , M. A. Gama Sosa 1 , R. De Gasperi 1 , G. A. Elder 3 and J. D. Buxbaum 1 , (1)Mount Sinai School of Medicine, (2)INSERM, (3)Mount Sinai School of Medicine, James J. Peters VA Medical Center 3:00 144 130.123 Infl uence of Partner Cues On Social Behaviors in the BTBR Mouse Model of Autism. M. Yang*, A. M. Katz, M. Weber and J. N. Crawley, National Institute of Mental Health, National Institutes of Health 1:00 145 130.124 Modeling An Autism Risk Factor in Mice Leads to Permanent Changes in the Immune System. E. Hsiao*, California Institute of Technology 48 9th Annual International Meeting For Autism Research (IMFAR) 2010
2:00 146 130.125 Neonatal Administration of Propionic Acid Alters Startle Response Magnitude in Adolescent Rats. K. A. Foley*, L. J. Tichenoff, K. -. P. Ossenkopp and D. F. MacFabe, University of Western Ontario 3:00 147 130.126 Neuroligin-Defi cient Mutants of C. Elegans Have Sensory Defi cits and Are Hypersensitive to Oxidative Stress. J. B. Rand* 1 , J. W. Hunter 2 , G. P. Mullen 1 and J. M. Heatherly 2 , (1)Oklahoma Medical Research Foundation, (2)Oklahoma Medical Research Foundation/ University of Oklahoma Health Sciences Center 1:00 148 130.127 Scent Marking as a Measure of Olfactory Communication in Shank1 Null Mutant Mice. F. I. Roullet* 1 , R. Saxena 1 , M. Wöhr 1 , A. Y. Hung 2 , M. Sheng 2 and J. N. Crawley 3 , (1)National Institute of Mental Health, (2)Massachusetts Institute of Technology, (3)National Institute of Mental Health, National Institutes of Health 2:00 149 130.128 The Dog as a Genetic Model to Investigate Overlap in Social, Attention, and Activity Behaviors. L. Lit*, D. Bannasch and J. Schweitzer, University of California at Davis 3:00 150 130.129 A Role for HGF/SF-Met Signaling in the Developing Cortex. J. M. Smith*, G. J. Martins, C. Plachez and E. M. Powell, University of Maryland School of Medicine 1:00 151 130.130 Comprehensive Behavioral Phenotyping of Neuroligin 2 Mutant Mice. S. Turner*, D. D. Diagne, M. J. Harris, R. Saxena, J. L. Silverman and J. N. Crawley, National Institute of Mental Health, National Institutes of Health 2:00 152 130.131 Development and Temporal Dynamics of Repetitive Behavior. M. Lewis*, Y. Tanimura and M. Yang, University of Florida 3:00 153 130.132 Effects of Acute Serotonin Reuptake Inhibitor Treatment and Serotonin Depletion On Sociability in Juvenile BALB/Cj and C57BL/ 6J Mice. A. H. Fairless* 1 , E. Gordon 1 , R. Y. Shah 1 , H. C. Dow 1 , S. C. Allen 1 and E. S. Brodkin 2 , (1)University of Pennsylvania School of Medicine, (2)University of Pennsylvania 1:00 154 130.133 Longitudinal Assessment of Fgf17-/- Mouse Social Behavior On the C57Bl/6 Background. E. C. Ihle* 1 , K. Scearce-Levie 2 , N. Devidze 3 , R. Hoch 1 and J. L. Rubenstein 1 , (1)UCSF, (2)Genentech, (3)Gladstone Institute 2:00 155 130.134 Pharmacological Treatment of Repetitive Behavior in Deer Mice: Targeting Striatal Heteromeric Receptor Complexes. A. M. Van Matre* and M. Lewis, University of Florida 3:00 156 130.135 The Impact of Gabrb3 Expression Variation On Autism Spectrum Disorder Related Phenotypes in Mouse. L. Herzing*, S. Zeng, N. Chiu, M. Yasvoina and K. Kugle, Northwestern University Feinberg School of Medicine 1:00 157 130.136 Behavioral Phenotypes of Shank1 Mutant Mice. J. L. Silverman* 1 , C. L. Barkan 1 , S. S. Tolu 1 , S. Turner 1 , R. Saxena 1 , D. D. Diagne 1 , A. Y. Hung 2 , M. Sheng 2 and J. N. Crawley 1 , (1)National Institute of Mental Health, National Institutes of Health, (2)Massachusetts Institute of Technology Program 2:00 158 130.137 Constructing a Transgenic Mouse Model Based On SLC25A12, MARK1 and PRKCB1 Gene Dosage Imbalance Mimicking Gene Expression Changes Found in Brain of ASD Patients. A. M. Lepagnol-Bestel 1 , J. M. Moalic 1 , J. Hager 2 and M. J. Simonneau* 1 , (1)INSERM U894, (2)IntegraGen 3:00 159 130.138 Intraventricular Infusions of Enteric Short Chain Fatty Acids Induce Behavioural, Neuropathological and Epigenetic Changes in Rats- Further Development of a Novel Rodent Model of Autism. D. F. MacFabe* 1 , R. Agarwal 2 , L. J. Tichenoff 1 , A. R. Taylor 1 , E. LaGamma 2 and B. B. Nankova 2 , (1)University of Western Ontario, (2)New York Medical College/Westchester Medical Centre, Valhalla NY, USA 1:00 160 130.139 The Human AVPR1A BAC Transgenic Mouse: Generation and Validation of a Preclinical Model for Elucidating the Role of AVPR1A in Autism Spectrum Disorders. R. A. Charles* 1 , T. Sakurai 2 , M. A. Gama Sosa 2 , G. A. Elder 3 , L. J. Young 4 and J. D. Buxbaum 2 , (1)Mount Sinai School of Medicine, Seaver Autism Center, (2)Mount Sinai School of Medicine, (3)Mount Sinai School of Medicine, James J. Peters VA Medical Center, (4)Emory University 2:00 161 130.140 Transient Expression of Serotonin 5-HT4 Receptors in the Developing Thalamocortical Projections. S. Janusonis*, E. Slaten, M. Hernandez, A. Chen, R. Albay and R. Lavian, University of California, Santa Barbara 3:00 162 130.141 Changing GABAergic Tone Infl uences Prefrontal Mediated Cognition. G. B. Bissonette* 1 , M. Bae 1 , T. Suresh 1 , G. Schoenbaum 1 and E. M. Powell 2 , (1)University of Maryland, Baltimore, (2)University of Maryland School of Medicine 1:00 163 130.142 Preferential Differentiation of TH17 Cells in Offspring of Immune- Activated Dams in a Prenatal Mouse Model of Autism. M. Mandal* 1 , A. Marzouk 2 , R. Donnelly 3 and N. M. Ponzio 2 , (1)UMDNJ - Graduate School of Biomedical Sciences, (2)UMDNJ - New Jersey Medical School, (3)UMDNJ - New Jersey Medical School and Graduate School of Biomedical Sciences Poster Sessions 130 Brain Imaging 1:00 PM - 5:30 PM - Franklin Hall B Level 4 1:00 22 130.001 fMRI of Citalopram Treatment in Autism. S. Greeter 1 , L. Sikich 2 , C. Alderman 2 , A. Rittenberg 2 , L. Turner-Brown 3 , T. Holtzclaw* 4 , J. W. Bodfi sh 5 , J. Richey 4 and G. Dichter 2 , (1)University of North Carolina School of Medicine, (2)University of North Carolina, (3)UNC- Chapel Hill, (4)Carolina Institute for Developmental Disabilities, (5)University of North Carolina - Chapel Hill 2:00 23 130.002 Meta-Analysis of Functional Neuroimaging Studies Reveals Enhanced Engagement of Visual System in Autism. F. Samson* 1 , T. A. Zeffi ro 2 , I. Soulières 1 and L. Mottron 1 , (1)Centre d’excellence en Troubles envahissants du développement de l’Université de Montréal (CETEDUM), (2)Neural Systems Group, Massachussetts General Hospital FrIday –PM 9th Annual International Meeting For Autism Research (IMFAR) 2010 49
Page 1 and 2: 9th Annual International Meeting Fo
Page 3 and 4: Welcome IMFAR Welcome Welcome to IM
Page 5 and 6: IMFAR 2010 Scientific Program Dear
Page 7 and 8: IMFAR 2010 Awardees Professionals f
Page 9 and 10: Scientific Program Committee Member
Page 11 and 12: Contents Contents Welcome _________
Page 13 and 14: Hotel Floor Plan Fifth Floor Grand
Page 15 and 16: 10:00 101.001 Imaging Genetics: Tra
Page 17 and 18: 9:00 15 105.015 Relationships Among
Page 19 and 20: 9:00 60 105.060 Receptive and Expre
Page 21 and 22: 10:00 105 105.105 High-Risk Infants
Page 23 and 24: Program Invited Educational Symposi
Page 25 and 26: Lifetime Achievement Award and Pres
Page 27 and 28: 3:00 36 111.036 Executive Function
Page 29 and 30: 1:00 80 111.080 The Social Communic
Page 31 and 32: Program 1:00 125 111.125 The Use of
Page 33 and 34: Program 3:00 171 111.171 Early Inte
Page 35 and 36: Program Oral Sessions 115 Model Sys
Page 37 and 38: 19 117.025 Self-Monitoring with Han
Page 39 and 40: 10:00 134 118.134 Default Network C
Page 41 and 42: 10:00 176 118.176 Rapid Assessment
Page 43 and 44: 11:00 71 118.071 Individuals with A
Page 45 and 46: Program Friday May 21 - PM 1:15-3:1
Page 47 and 48: Program Scientific Panels 123 Devel
Page 49: Program 5:30 126.008 Whole Genome B
Page 53 and 54: 3:00 45 130.024 Volumetric Brain Di
Page 55 and 56: 2:00 93 130.072 Using the Anxiety D
Page 57 and 58: 2:00 121 130.100 The Double ABCX Mo
Page 59 and 60: Program 10:30 133.004 Multimodal MR
Page 61 and 62: 9:00 19 136.019 Eye Gaze Patterns o
Page 63 and 64: 11:00 89 136.089 AUTISM Spectrum Di
Page 65 and 66: 11:00 47 136.047 Effects of Repetit
Page 67 and 68: Program 12:00-1:00P Business Meetin
Page 69 and 70: Index Author Name Email Address Abs
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Index Author Name Email Address Abs
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Exhibitors Aldebaran-Robotics Nao i
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INSAR 2010 Sponsors We thank the fo
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