directory of the spanish nanotechnology community - Fundación ...

Capacities
UNIT OF EXPERIMENTAL TOXICOLOGY AND
ECOTOXICOLOGY (UTOX)
University Research Centre Public Centre SME Large Company
characterization nanocomposites nanosensors synthesis/funct nanophotonics
nanobiotechnology nanoadditives nanometrology nanosimulation nanoencapsulates
Address
c/ Baldiri Reixac 10-12
Edifici Clúster PCB
08028 Barcelona
Webpage:
http://www.pcb.ub.edu/homepcb/live/en/p884.asp
Contact information
Joaquín de Lapuente Pérez
Lab and Project Manager
Tel: +34 934037195
Fax: +34 934037109
e-mail: jlapuente@pcb.ub.cat
Organization profile
The Unit of Experimental Toxicology and Ecotoxicology (UTOX) is positioned as the Platform of Toxicology
from the Barcelona Science Park (PCB) and as a Centre of Research, Innovation and Services in toxicology
with more than 10 years of experience, serving both the public and the private sector while conducting their
own research projects or in collaboration with other research groups. Simultaneously, UTOX is part of GRET
(Group consolidated for Research in Toxicology) and CERETOX (Toxicology research center, TECNIO
agent) together with the Toxicology Unit, Faculty of Pharmacy of Barcelona University (UB).
Main capacities in nanotechnology / nanoscience
Our laboratory is able to perform different types of assays to evaluate the risk associated to nanomaterials
according to the required quality (GLP). We propose, as more suited for nanomaterials, the following:
Toxicology
o
o
o
o
o
Ecotoxicology
o
o
o
o
Systemic toxicity: (all routes of administration)
• In vivo: acute exposure and repeated dose
• In vitro: cytotoxicity test (MTT) in different cell lines (A-549, HepG2, HaCat…)
Genotoxicity: Micronucleus test (MNT), Mouse Lymphoma, cromosomic aberrations, Comet
Assay and Ames test.
Carcinogenicity: Cell Transformation Assay (CTA)
Reprotoxicity: WEC, Micromass, Embryonic Stem-cell Test (EST)
Local effects and sensitization (including phototoxicity)
Seed germination and growing test
Eisenia foetida lethality test
Daphnia immobilization test
Embriotoxicity test in zebrafish embryos (Fish Embryo Teratogenicity assay, FET)
Directory of the Spanish Nanotechnology Community Page 78 of 134