Exhibit 8, 100416 Brazil FMD Risk Evaluation - R-Calf

provide CSFV-FMDV diagnostics. These individuals have been working at the
laboratory for at least 10 years.
The laboratory is old but well maintained and reasonably equipped.
The site visit team found the laboratory personnel highly qualified and motivated. The
team also found that they have the equipment necessary to detect disease.
The turnaround time for results is excellent, avoiding the extension of quarantine time on
farms and States affected by an epidemiological alert.
The laboratory has SOPs (standard operating procedures) and QA (quality assurance)
control for, at least, the two tests the site visit team scrutinized. The procedures for
CSFV and FMDV diagnosis are well established and are suited for both detection and
confirmation of the etiologic agent. They are:
o FMDV: Surveillance and transport certificates and sera samples are sent to
accredited laboratories in Rio Grande do Sul, Sao Paulo, Minas Gerais and Mato
Grosso. Inconclusive ELISA/ITB results go to Recife. If a clinical case is reported,
the DSA direct that the samples be sent to LANAGRO to perform VIAA or ELISA
3ABC/EITB. If a case ends up with suspected positive results, an alert is sent to the
DSA and CGAL (General Coordination for Animal Laboratories) authorities who in
turn will implement their control and eradication policies.
o CSFV: The same accredited laboratories perform ELISA for CSFV antibodies in
sera. Any serum-positive or inconclusive result is sent to LANAGRO-Recife for
confirmation. If a clinical case is reported, the samples go to LANAGRO-Recife
only, where VIAA, virus neutralization, and/or ELISA are performed. If the result is
confirmed as positive, the authorities take the appropriate measures for control and
eradication.
Conclusions:
APHIS concludes that Brazil has the diagnostic capability to adequately test samples for the
presence of the FMD, CSF, SVD, and ASF virus. The laboratories in Pedro Leopoldo, Pará, and
Recife have adequate diagnostic capabilities to test samples for the FMD virus, including adequate
quality control activities, laboratory equipment, and sufficient staff. The Recife laboratory has
adequate diagnostic capabilities to test samples for FMD and other swine notifiable diseases. The
tests used to investigate evidence of viral activity are consistent with OIE guidelines. The staff
members at the facilities visited in 2002 and 2008 were well trained and motivated. The laboratories
have sufficient quality control activities, routinely monitor and calibrate laboratory equipment, have
sufficient staff, have an effective and efficient recordkeeping system for storage and retrieval of data,
and turn samples around quickly.
11. Policies and infrastructure for animal disease control in the region
Each country should have contingency plans in place to limit any disease outbreak. In this section
we provide an overview of the elements of Santa Catarina’s emergency plan if suspect cases of
FMD, CSF, SVD, and ASF are identified.
The Brazilian government has developed a Federal contingency plan for FMD and CSF. Each State
also drafts a specific contingency plan for immediate, effective action in an emergency. Each State
APHIS Evaluation of the Status of the Brazilian State of Santa Catarina 57