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ΝΟΣΟΚΟΜΕΙΑΚΑ ΧΡΟΝΙΚΑ, ΤΟΜΟΣ 74, ΣΥΜΠΛΗΡΩΜΑ 2, 2012 207
ευαισθησία για την διάγνωση του καρκίνου παχέος
εντέρου με συχνά παθολογικές τιμές σε καλοήθεις
παθήσεις και αρνητικά αποτελέσματα σε αρχόμενη
νόσο. Για το λόγο αυτό η American Society of Clinical
Oncology (ASCO) (38,39) και European Group on Tumor
Markers συνιστά να μη χρησιμοποιείται κάποιος καρκινικός
δείκτης για το έλεγχο ασυμπτωματικών ασθενών
για ΚΠΕ. Φαίνεται ωστόσο ότι τουλάχιστον το CEA έχει
προγνωστική αξία, αφού οι ασθενείς με παθολογική
τιμή έχουν χειρότερη πρόγνωση σε σχέση με ασθενείς
με ίδιο στάδιο νόσο και φυσιολογικό CEA. Βεβαίως η
παραμονή υψηλής τιμής μετεγχειρητικά ή η εκ νέου
αύξηση αυτής κατά την παρακολούθηση είναι δείκτης
υπολειμματικής ή υποτροπής νόσου, αντίστοιχα.
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