The Questions of Developmental Biology

Fig.11.27
Fig. 11.28
Those cells migrating through the node give rise to the notochord. However, in contrast
to notochord formation in the chick, the cells that form the mouse notochord are thought to
become integrated into the endoderm of the primitive gut (Jurand 1974; Sulik et al. 1994). These
cells can be seen as a band of small, ciliated cells extending rostrally from the node (Figure
11.29). They form the notochord by converging medially and folding off in a dorsal direction
from the roof of the gut.