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R.A. Irizarry 17516.4 The bright futureI think that the data revolution is just getting started. Datasets are currentlybeing, or have already been, collected that contain, hidden in their complexity,important truths waiting to be discovered. These discoveries will increasethe scientific understanding of our world. Statisticians should be excited andready to play an important role in the new scientific renaissance driven by themeasurement revolution.ReferencesCrone, N.E., Hao, L., Hart, J., Boatman, D., Lesser, R.P., Irizarry, R., andGordon, B. (2001). Electrocorticographic gamma activity during wordproduction in spoken and sign language. Neurology, 57:2045–2053.DiPietro, J.A., Irizarry, R.A., Hawkins, M., Costigan, K.A., and Pressman,E.K. (2001). Cross-correlation of fetal cardiac and somatic activity as anindicator of antenatal neural development. American Journal of Obstetricsand Gynecology, 185:1421–1428.Gautier, L., Cope, L., Bolstad, B.M., and Irizarry, R.A. (2004). Affyanalysisof affymetrix genechip data at the probe level. Bioinformatics, 20:307–315.Gentleman, R.C., Carey, V.J., Bates, D.M., Bolstad, B., Dettling, M., Dudoit,S., Ellis, B., Gautier, L., Ge, Y., Gentry, J. et al. (2004). Bioconductor:Open software development for computational biology andbioinformatics. Genome Biology, 5:R80.Irizarry, R.A. (2001). Local harmonic estimation in musical sound signals.Journal of the American Statistical Association, 96:357–367.Irizarry, R.A., Hobbs, B., Collin, F., Beazer-Barclay, Y.D., Antonellis, K.J.,Scherf, U., and Speed, T.P. (2003). Exploration, normalization, and summariesof high density oligonucleotide array probe level data. Biostatistics,4:249–264.Irizarry, R.A., Ladd-Acosta, C., Wen, B., Wu, Z., Montano, C., Onyango, P.,Cui, H., Gabo, K., Rongione, M., Webster, M. et al. (2009). The humancolon cancer methylome shows similar hypo- and hypermethylation atconserved tissue-specific CpG island shores. Nature Genetics, 41:178–186.Irizarry, R.A., Tankersley, C., Frank, R., and Flanders, S. (2001). Assessinghomeostasis through circadian patterns. Biometrics, 57:1228–1237.

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