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Continued from page 37 – Data show Correlations betweenIncrease in Neurological Diseases and GMOsAll formulations were more potent than purifiedglyphosate (at similar levels to R360) in causing celldeath. Surprisingly, R400 containing less glyphosate wasmore toxic to human liver cells than R450.In the study, exposure of a single gene regulated by eitherestrogen or androgen hormones demonstrated that allformulations disrupt hormone function more efficientlythan purified glyphosate. The findings show that theformulations act against the hormones to produce antiestrogenicand anti-androgenic effects.http://www.environmentalhealthnews.org/ehs/newscience/roundup-mix-more-toxic-to-liver-cells-than-glyphosate/☻☻☻☻☻New Review Links Roundupto Diabetes, Autism, Infertilityand CancerApril 18, 2013A new peer-reviewed scientific review paper has beenreleased in the US stating that glyphosate-basedherbicides such as Roundup are contributing togastrointestinal disorders, obesity, diabetes, heart disease,depression, autism, infertility, cancer and Alzheimer’sdisease.The review paper states that “glyphosate enhances thedamaging effects of …food borne chemical residues andenvironmental toxins. Negative impact on the body isinsidious and manifests slowly over time as inflammationdamages cellular systems throughout the body. Here, weshow how interference with CYP enzymes acts syner-gistically with disruption of the biosynthesis of aromaticamino acids by gut bacteria, as well as impairment inserum sulfate transport. Consequences are most of thediseases and conditions associated with a Western diet,which include gastrointestinal disorders, obesity,diabetes, heart disease, depression, autism, infertility,cancer and Alzheimer’s disease.”For the full study click here .“The paper gives good arguments why it’s vital to opposethe recent capitulation by UK supermarkets to acceptingproducts from animals raised on GM feed,” GM Watchstated.Glyphosate (N-phosphonomethylglycine), the activeingredient in the herbicide Roundup®, is the mainherbicide in use today in the United States, andincreasingly throughout the World, in agriculture and inlawn maintenance, especially now that the patent hasexpired. 80% of genetically modified crops, particularlycorn, soy, canola, cotton, sugar beets and most recentlyalfalfa, are specifically targeted towards the introductionof genes resistant to glyphosate, the so-called “RoundupReady® feature”. In humans, only small amounts (~2%)of ingested glyphosate are metabolizedto aminomethylphosphonic acid (AMPA), and the restenters the blood stream and is eventually eliminatedthrough the urine.Studies have shown sharp increases in glyphosatecontamination in streams in the Midwestern United Statesfollowing the mid 1990s, pointing to its increasing role asthe herbicide of choice in agriculture. A now commonpractice of crop desiccation through herbicide administrationshortly before the harvest assures an increasedglyphosate presence in food sources as well. The industryasserts that glyphosate is nearly nontoxic to mammals,and therefore it is not a problem if glyphosate is ingestedin food sources. Acutely, it is claimed to be less toxicthan aspirin. As a consequence, measurement of itspresence in food is practically nonexistent.A vocal minority of experts believes that glyphosate mayinstead be much more toxic than is claimed, although theeffects are only apparent after a considerable time lapse.Thus, while short-term studies in rodents have shown noapparent toxicity, studies involving life-long exposure inrodents have demonstrated liver and kidney dysfunctionand a greatly increased risk of cancer, with shortenedlifespan.http://sustainablepulse.com/2013/04/18/new-study-linksroundup-to-diabetes-autism-infertility-andcancer/#.Uezu46zhcWk☻☻☻☻☻38-- Traditional African Clinic July 2013
African Traditional Herbal Research ClinicVolume 8, Issue 6 NEWSLETTER July 2013FEATURED ARTICLESWide Range of Diseases Linked to PesticidesDatabase Supports Policy Shift from Risk to AlternativesAssessmentBy Kagan Owens, Jay Feldman and John KepnerPesticide-Induced Diseases DatabaseBeyondpesiticides.orgThe common diseases affecting the public’s healthare all too well-known in the 21st century: asthma,autism and learning disabilities, birth defects andreproductive dysfunction, diabetes, Parkinson’s andAlzheimer’s diseases, and several types of cancer.Their connection to pesticide exposure continues tostrengthen despite efforts to restrict individualchemical exposure, or mitigate chemical risks, usingrisk assessment-based policy.The Pesticide-Induced Diseases Database, launchedby Beyond Pesticides, facilitates access toepidemiologic and laboratory studies based on realworld exposure scenarios that link public healtheffects to pesticides. The scientific literaturedocuments elevated rates of chronic diseases amongpeople exposed to pesticides, with increasingnumbers of studies associated with both specificillnesses and a range of illnesses. With some ofthese diseases at very high and, perhaps, epidemicproportions, there is an urgent need for publicpolicy at all levels –local, state, and national—toend dependency on toxic pesticides, replacing themwith carefully defined green strategies.Data Supports Policy ChangeThe database is a tool to support efforts to eliminatethe continued use of hazardous pesticides in favorof green strategies that emphasize non-toxic andleast-toxic alternative practices and products. Thestudies in the database show that our currentapproach to restricting pesticide use through riskassessment-based mitigation measures is notworking. This failed human experiment must beended. The warnings of those who have expressedconcerns about risk assessment, such as EPAAdministrator under Presidents Nixon and Reagan,William Ruckelshaus, have been borne out by threedecades of use and study. Mr. Ruckelshaus in 1984said, “We should remember that risk assessment datacan be like the captured spy: If you torture it longenough, it will tell you anything you want to know.”EPA’s risk assessment fails to look at chemicalmixtures, synergistic effects, certain health endpoints(such as endocrine disruption), disproportionate effectsto vulnerable population groups, and regularnoncompliance with product label directions. Thesedeficiencies contribute to its severe limitations indefining real world poisoning, as captured byepidemiologic studies in the database.An enlightened policy approach to proposed orcontinued toxic chemical use, in an age where theadverse effects have been widely and increasinglydocumented, is to first ask whether there is a less toxicway of achieving the toxic chemical’s intendedpurpose. Simply, “Is there another practice that wouldmake the substance unnecessary?” This approach doesnot preclude and should demand the prohibition ofhigh hazard chemical use, those chemicals that aresimply too dangerous.The alternatives assessment approach differs mostdramatically from a risk assessment-based policy is inrejecting uses and exposures deemed acceptable underrisk assessment calculations, but unnecessary becauseof the availability of safer alternatives.39-- Traditional African Clinic July 2013For example, in agriculture, where the database showsclear links to pesticide use and cancer, it would nolonger be possible to use hazardous pesticides, as it iswith risk assessment-based policy, when there areclearly effective organic systems with competitiveyields that, in fact, outperform chemical-intensiveContinued on page 40
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