CAGE PROCESSING in Animal Facilities - Felasa

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If there are already problems with incorrect treated bottle caps, a prolonged washing cycle using alkalinedetergent must be conducted. A pre-treatment is required for oily or fatty remainders of 20 minutes in an ultrasonicbath with 5% alkaline detergent solution, followed by a normal washing cycle of the caps and finally aprolonged post cleaning with fresh demineralised water.A simple procedure is in place to test the performance of the bottle nipple, the trouble-free water flow. (Couldbe performed on a regular basis or when needed):• Fill a bottle with water• Close it with the cap• Position the filled bottle into the bottle depression of a cage/IVC lid• Wait for 20 seconds, till water and air are in balance• Touching the top of the nipple with the finger, a water drop has to be pulled off/released (see figure 9-7) –is this not possible above mentioned causes and measures should be evaluatedFigure 9-7 Bottle nipple with water drop (finger test to pull off the drop)Bottle caps and their proper functioning are essential for animals and their life. All persons involved withinlaboratory animal facilities are commited to exercise special care.Conclusion to 9.1 - 9.6:Usually, the defects and damages described above do not result from insufficient product quality of items.What must be considered, however, is a careful selection and adaptation of influencing factors (items to beprocessed, washer, process chemicals, sterilisers, SOPs, etc.).9.7 Criteria for screening damaged materialBeside the above-mentioned changes in material, a normal washing and steam sterilisation process will causematerial induced deterioration that can make it necessary for certain items to be replaced. Therefore, theseitems should be scheduled for regular material fitness checks.10 Literature, standards, publicationsNormative referencesDIN 31051 (German Institute for Standardization): Physical Assets MaintenanceDIN 4140: Insulation Work on Industrial Installations and Building Equipment – Execution of Thermal and ColdInsulationsEN 285 (European standard for products and services): Steam sterilisation; Steam Sterilisers; Large SterilisersDIN 58951: Steam Sterilisers for Laboratory UseISO 8573-1(International Organisation for Standardization): Compressed air – Part 1: Contaminants and PurityClassesDIN EN VDE 0100: Regulations for Building High Voltage Systems with Nominal Voltage up to 1000 V66Cage Processing in Animal Facilities · 4th issue · 2013
DIN 1986:Technical Rules for Drinking Water Installations – Drainage systems on private ground, Animal Laboratories007, bulletin BG ChemieDIN 10510: Food Hygiene – Commercial Dishwashing with Multitank-transport Dishwashers – Hygienic Requirements,Type TestingDIN 10511: Food Hygiene – Commercial Glasswashing with Glasswashing machines – Hygienic Requirements,Type TestingDIN 10512: Food Hygiene – Commercial Dishwashing with Onetank-Dishwashers – Hygienic Requirements,Type TestingDIN 58955: Decontamination Equipment for Medical UseDIN EN 12353: Chemical Disinfectants and Antiseptics – Preservation of Test Organisms Used for Determinationof Bactericidal, Mycobactericidal, Sporicidal and Fungicidal ActivityDIN 10088-1: Rustproof Steels – Part 1: Index of Rustproof SteelsDirectives / regulationsRecommendations of the GV-SOLAS:Please refer to: www.gv-solas.deAppendix A of the European Council, ETS 123 Official Journal of the European Union from 30.07.2007(2007/526/EG)Please refer to: www.gv-solas.deDIRECTIVE 2010/63/EU OF THE EUROPEAN PARLIAMENT AND OF THE COUCIL of 22 September 2010on the Protection of animals used for scientific purposesPlease refer to: www.gv-solas.deTRGS 906 – Technical guideline for the handling of hazardous materials, Directory of carcinogenic operationsor procedures according to §3 paragraph 2 No. 3 GefStoffVTRGS 540 - Technical guideline for the handling of hazardous materials, sensitizing substancesTRGS 553 - Technical guideline for the handling of hazardous materials, wood dustTRGA 120 – Technical guideline for biological agents at work - experimental animal facilitiesDirective 2004/37/EC of the European Parliament and of the Council on the protection of workers from therisks related to exposure to carcinogens or mutagens at work, appendix I, No.5Machinery directive 2006/42/ECPublications„Leitfaden für die Praxis: Dampfversorgung zur Sterilisation von Medizinprodukten“ ; überarbeitete Neuauflage2005. Herausgeber AK-Steri-Dampf(Practical guide: Steam supply for sterilising medical items, revised new issue 2005 by AK-Steri-Dampf)“Instrumenten-Aufbereitung im Veterinärbereich richtig gemacht”, „Grüne Broschüre“, 1. Ausgabe 2005.Herausgeber: Arbeitskreis Instrumenten-Aufbereitung(Proper Maintenance of Instruments in Veterinary surgeries, Green Brochure, 1 st issue 2005, by the WorkingGroup for Instrument Processing)AK-BWA Broschüre, 8. Auflage, 2009(AK-BWA brochure, 8 th issue 2009)Current state of room decontamination using gaseous hydrogen peroxide, Hygiene & Medizin, 35 [6]; 204-208Cage Processing in Animal Facilities · 4th issue · 2013 67
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CAGE PROCESSINGin Animal Facilities
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CAGE PROCESSINGin Animal Facilities
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Index1 Introduction ...............
Page 7 and 8:
7.1 Requirements ..................
Page 9 and 10:
2 Cage processing cyclesThe followi
Page 11 and 12:
3.2 Materials for processingWhen de
Page 13 and 14:
• They should be easy and conveni
Page 15 and 16:
• Height-adjustable shelves ensur
Page 17 and 18: Table 4-2Option Advantages Disadvan
Page 19 and 20: Below you will find a description o
Page 21 and 22: Figure 4-10 Tunnel cage washer4.3.1
Page 23 and 24: WashingHot water mixed with deterge
Page 25 and 26: Loading systemsIn cabinet cage wash
Page 27 and 28: 4.3.2.1.3 Rinse aidRinse aids shoul
Page 29 and 30: Semiautomaticdispensing*bedding is
Page 31 and 32: Semi-automaticsystemsmultiple filli
Page 33 and 34: PermissionsWith frequent changes in
Page 35 and 36: 4.6.2.1 Basic lock types for H 2O 2
Page 37 and 38: configurations can thus require ind
Page 39 and 40: 4.6.3.2 Processual requirementsPAA
Page 41 and 42: Lead mg/l -heavy metal residues (ex
Page 43 and 44: For reasons of odour, exhaust air o
Page 45 and 46: 5.6 Installation data and consumpti
Page 47 and 48: 6.2 Start up of operationIt is part
Page 49 and 50: 6.9 Routine checks and measuresThe
Page 51 and 52: 7.2.1.1.2 Test setup1 inside at the
Page 53 and 54: 7.2.2 Test procedures for evaluatin
Page 55 and 56: surfaces stay soil free. For an eve
Page 57 and 58: 7.4 Test procedure for confirming t
Page 59 and 60: Table 7-6WasherItems for processing
Page 61 and 62: with rinse aid, for example, can be
Page 63 and 64: 9 Potential defects and damages in
Page 65 and 66: Table 9-3Source and causesStress /
Page 67: Table 9-6Sources and causesWashing
Page 71 and 72: Detergent liquor / detergent soluti
Page 73 and 74: ProcessingProcessing means washing,
Page 75 and 76: Final provisions:1. This brochure d
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CAGE PROCESSING in Animal Facilities - Felasa

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