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CAGE PROCESSING in Animal Facilities - Felasa

CAGE PROCESSING in Animal Facilities - Felasa

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Process<strong>in</strong>gProcess<strong>in</strong>g means wash<strong>in</strong>g, dis<strong>in</strong>fect<strong>in</strong>g, and sterilis<strong>in</strong>g all items that are transferred from the process<strong>in</strong>g centre(or wash-up area) to the animal hous<strong>in</strong>g area, <strong>in</strong>clud<strong>in</strong>g all associated empty<strong>in</strong>g, fill<strong>in</strong>g, and transport<strong>in</strong>g/carry<strong>in</strong>g activities.Process<strong>in</strong>g centrePlease refer to wash-up area.Recirculation systemIn the recirculation system of a washer the spray water mixed with detergents is recirculated and thus repeatedlysprayed on the items to be processed.Scoop<strong>in</strong>g cavitiesHollows and areas on items that are prone to accumulat<strong>in</strong>g residual liquid and dirt.SOPStandard Operation ProceduresSPF areaArea for hous<strong>in</strong>g and breed<strong>in</strong>g specific pathogen free animals.Spray waterSpray water is the water <strong>in</strong> automated washers, potentially mixed with process chemicals, that is pressure-sprayedvia jets on items for process<strong>in</strong>g.Steam sterilisationA validatable procedure for remov<strong>in</strong>g viable microorganisms.Thermo labile and thermo stable itemsRefer to chapter 4.5.1.1TitrationTitrimetric method for determ<strong>in</strong><strong>in</strong>g the amount of substances <strong>in</strong> liquids (method for def<strong>in</strong><strong>in</strong>g the substance concentration).Drops of a reagent of known concentration (standard solution) are added with a burette to a givensubstance till the concentration is even and the <strong>in</strong>dicator <strong>in</strong> the standard solution shows a colour change.Tolerable residual moistureA tolerable residual moisture means s<strong>in</strong>gle water drops (no puddles of water) adher<strong>in</strong>g to items <strong>in</strong> adversespots after be<strong>in</strong>g removed from the washer. Subsequent steps of item process<strong>in</strong>g are not affected.Wash<strong>in</strong>gRemov<strong>in</strong>g soil<strong>in</strong>g off objects to a degree necessary for further process<strong>in</strong>g or designated use.Wash-up areaAll mach<strong>in</strong>es necessary for wash<strong>in</strong>g, dis<strong>in</strong>fection, and steam sterilisation of items are located <strong>in</strong> close vic<strong>in</strong>ity<strong>in</strong> the wash-up area (also process<strong>in</strong>g centre).Work exposure limit (WEL)The work exposure limit (WEL) describes the limit of the time-assessed average concentration of a substance<strong>in</strong> workplace air for a given reference period. It <strong>in</strong>dicates the safe concentration of a substance where noacutely or chronically harmful effects on health <strong>in</strong> general can be expected. The limit is generally based on apresumed eight hour exposure to a substance five days a week of an entire work<strong>in</strong>g life. The work exposurelimit is <strong>in</strong>dicated <strong>in</strong> mg/m³ and ml/m³ (ppm). (Please consult the ord<strong>in</strong>ance on hazardous substances as def<strong>in</strong>edby your respective country/EU standards.)Cage Process<strong>in</strong>g <strong>in</strong> <strong>Animal</strong> <strong>Facilities</strong> · 4th issue · 2013 71

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